Insights from Imaging in Bioinorganic Chemistry /

Annotation

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Eldik, Rudi van (Editor ), Hubbard, Colin D. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cambridge, MA : Academic Press, 2016.
Edición:First edition.
Colección:Advances in inorganic chemistry ; volume 68.
Temas:
Bioinorganic chemistry.
Imaging systems in chemistry.
Chimie bio-inorganique.
Imagerie en chimie.
SCIENCE / Life Sciences / Biochemistry
Bioinorganic chemistry
Imaging systems in chemistry
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover
  • Insights from Imaging in Bioinorganic Chemistry
  • Copyright
  • Contents
  • Contributors
  • Preface
  • Chapter One: Opportunities and Challenges for Metal Chemistry in Molecular Imaging: From Gamma Camera Imaging to PET and ...
  • 1. Introduction
  • 2. Technetium-99m: Small Complexes
  • 2.1. From Serendipity to Design
  • 2.2. Tc(I)tricarbonyl
  • 2.3. Tc(V) Complexes
  • 2.4. Bioconjugates: A New Challenge
  • 2.5. Bioconjugation with Hynic
  • 2.6. Bioconjugation with Other Bifunctional Chelators
  • 2.7. Bioconjugation with the ��Tricarbonyl Core�� Tc(CO)3+
  • 2.8. Bioconjugation by Direct Labeling Via Cysteine
  • 2.9. Rhenium Analogs
  • 2.10. Summary: Challenges in Tc-99m Chemistry
  • 3. The Transition Toward PET
  • 3.1. The Need for Metallic Positron Emitters
  • 3.2. Gallium-68: ��The New Technetium-99m��
  • 3.3. Zirconium-89: ��The New Indium-111��-ImmunoPET and Cell Tracking
  • 4. Copper: Exploiting Redox Chemistry
  • 4.1. Copper Isotopes and Bioconjugates
  • 4.2. Bioreductive Trapping-Imaging Blood Flow and Hypoxia
  • 4.3. Cell Tracking with Copper
  • 4.4. Copper Trafficking Pathways in Health and Disease.
  • 5. Inorganic Elements as Binding Sites for 18F-Fluoride
  • 6. Multimodality Imaging and Nanoparticulate Contrast Agents
  • 7. Summary and Conclusion
  • Acknowledgments
  • References
  • Chapter Two: Molecular Magnetic Resonance Imaging Probes Based on Ln3+ Complexes
  • 1. Introduction
  • 2. Responsive Probes
  • 2.1. Enzymes
  • 2.2. Zinc
  • 2.3. Neurotransmitters
  • 3. Peptide Targeting in Amyloid Diseases
  • 4. Bimodal Probes
  • 4.1. Small Molecular Bimodal MRI/Optical Probes
  • 4.2. Lanthanide-Based Liponanoparticles as Bimodal MRI and Optical Probes
  • 5. Novel Objects as Nanosized MRI Probes.
  • 5.1. MOFs
  • 5.2. Nanozeolites
  • 5.3. Polyrotaxanes
  • 6. Conclusions
  • Acknowledgments
  • References
  • Chapter three: Luminescent Iridium(III) and Rhenium(I) Complexes as Biomolecular Probes and Imaging Reagents
  • 1. Introduction
  • 2. Bioconjugation Reagents and Biomolecular Probes
  • 2.1. Bioconjugation Reagents
  • 2.2. Biomolecular Probes
  • 3. Cellular Probes and Imaging Reagents
  • 3.1. Biotin Complexes
  • 3.2. Hydrophobic Probes
  • 3.3. Ion Sensors
  • 3.4. Nitric Oxide Sensors
  • 3.5. Poly(ethylene glycol) and Poly(ethyleneimine) Complexes
  • 3.6. Sugar Conjugates.
  • 3.7. Bioorthogonal Probes
  • 4. Conclusion
  • Acknowledgments
  • References
  • Chapter Four: Metalloporphyrins for Medical Imaging Applications
  • 1. Introduction
  • 2. Fluorescence Imaging
  • 2.1. Phthalocyanine Dyes
  • 2.2. Nanoscale Structures
  • 2.3. FRET Systems
  • 3. Raman Imaging
  • 4. Gamma Imaging
  • 4.1. Indium-111
  • 4.2. Technecium 99m
  • 4.3. Gallium 67
  • 4.4. Other Radionuclides
  • 5. Positron Imaging (PET)
  • 5.1. Copper 64
  • 5.2. Gallium 68
  • 5.3. Other Isotopes
  • 6. Magnetic Resonance Imaging
  • 6.1. Gadolinium
  • 6.2. Manganese
  • 6.2.1. Macromolecular Structures.

Ejemplares similares