Tabla de Contenidos:
  • History of systemic lupus erythematosus
  • The patient
  • Epidemiology
  • Measuring disease activity
  • Disease development and outcomes
  • Socioeconomic aspects of systemic lupus erythematosus
  • Biomarkers in systemic lupus erythematosus
  • Overview of the pathogenesis of systemic lupus erythematosus
  • Systemic lupus erythematosus and the environment
  • Genes and genetics in human systemic lupus erythematosus
  • Hormones
  • The complement system in systemic lupus erythematosus
  • T cells
  • Integrating current thinking on peripheral B-celltolerance in lupus
  • Neutrophils in systemic lupus erythematosus
  • The role of dendritic cells in systemic lupus erythematosus
  • Cytokines
  • Toll-like receptors, systemic lupus erythematosus
  • The interferon system in lupus erythematosus
  • Humoral pathogenesis : Fc[gamma] receptors in autoimmunity and end-organ damage
  • Apoptosis, autophagy, and necrosis
  • Infections in early systemic lupus erythematosus pathogenesis
  • Origin of autoantibodies
  • Anti-DNA antibodies
  • Antihistone and antispliceosome antibodies
  • Immune complexes in systemic lupus erythematosus
  • Microrna in systemic lupus erythematosus
  • Oxidative stress in systemic lupus erythematosus : causes, consequences, and treatment
  • Reactive nitrogen intermediates in the pathogenesis of systemic lupus erythematosus
  • Epigenetics
  • What do mouse models teach us about human systemic lupus erythematosus?
  • Genes and genetics of murine systemic lupus erythematosus
  • Mechanisms of renal damage in systemic lupus erythematosus
  • Mechanisms of vascular damage in systemic lupus erythematosus
  • The mechanism of skin damage
  • Pathogenesis of tissue injury in the brain in patients with systemic lupus erythematosus
  • Constitutional symptoms and fatigue in systemic lupus erythematosus
  • The musculoskeletal system in systemic lupus erythematosus
  • Cutaneous lupus erythematosus
  • The clinical evaluation of kidney disease in systemic lupus erythematosus
  • The pathology of lupus nephritis
  • Cardiovascular disease in systemic lupus erythematosus
  • The lung in systemic lupus erythematosus
  • Gastrointestinal, hepatic, and pancreatic disorders in systemic lupus erythematosus
  • Systemic lupus erythematosus and infections
  • Malignancies in systemic lupus erythematosus
  • The nervous system in systemic lupus erythematosus
  • Overlap syndromes
  • Systemic lupus erythematosus and the eye
  • Pregnancy and fertility in systemic lupus erythematosus
  • Neonatal lupus : clinical spectrum, biomarkers, pathogenesis, and approach to treatment
  • Incomplete lupus
  • Childhood-onset systemic lupus erythematosus
  • Drug-induced lupus
  • Vasculitis in lupus
  • Pathogenesis of antiphospholipid syndrome
  • Antibodies and diagnostic tests in antiphospholipid syndrome
  • Clinical manifestations
  • Nonsteroidal anti-inflammatory drugs in systemic lupus erythematosus
  • Value of antimalarial drugs in the treatment of lupus
  • Systemic glucocorticoids
  • Cytotoxic-immunosuppressive drug treatment
  • Treatment of antiphospholipid syndrome
  • New treatments for systemic lupus erythematosus
  • Management lessons from clinical trials of kidney disease in systemic lupus erythematosus
  • Repositioning drugs for systemic lupus erythematosus.