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040 |a YDXCP  |b eng  |e rda  |e pn  |c YDXCP  |d N$T  |d OCLCQ  |d OPELS  |d OCLCF  |d COO  |d USU  |d MMU  |d TMC  |d OCLCO  |d UIU  |d OCLCO  |d OCLCQ  |d OCLCO  |d OCLCQ  |d Z5A  |d CASUM  |d OCLCO  |d MERER  |d OCLCQ  |d OCLCO  |d OCLCA  |d U3W  |d BUF  |d OCLCO  |d OCLCQ  |d D6H  |d NLE  |d UKMGB  |d OCLCO  |d OCLCA  |d LQU  |d OCLCQ  |d S2H  |d OCLCO  |d OCLCQ  |d OCL 
015 |a GBB6F4543  |2 bnb 
015 |a GBB6H8738  |2 bnb 
016 7 |a 017799484  |2 Uk 
016 7 |a 017691624  |2 Uk 
019 |a 981886556  |a 1105180402  |a 1105573713 
020 |a 9780128020098  |q (electronic bk.) 
020 |a 0128020091  |q (electronic bk.) 
020 |z 9780128019177  |q (paperback) 
020 |z 0128019174  |q (paperback) 
035 |a (OCoLC)933591214  |z (OCoLC)981886556  |z (OCoLC)1105180402  |z (OCoLC)1105573713 
050 4 |a RC924.5.L85 
060 4 |a 2016 E-016 
060 4 |a WD 380 
072 7 |a HEA  |x 039000  |2 bisacsh 
072 7 |a MED  |x 014000  |2 bisacsh 
072 7 |a MED  |x 022000  |2 bisacsh 
072 7 |a MED  |x 112000  |2 bisacsh 
072 7 |a MED  |x 045000  |2 bisacsh 
082 0 4 |a 616.7/72  |2 23 
082 0 4 |a 616.77  |2 22 
245 0 0 |a Systemic lupus erythematosus :  |b basic, applied and clinical aspects /  |c edited by George C. Tsokos. 
264 1 |a London :  |b Academic Press is an imprint of Elsevier,  |c [2016] 
264 4 |c �2016 
300 |a 1 online resource (xxv, 600 pages) :  |b illustrations (chiefly color) 
336 |a text  |b txt  |2 rdacontent 
336 |a still image  |b sti  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references. 
505 0 |a History of systemic lupus erythematosus -- The patient -- Epidemiology -- Measuring disease activity -- Disease development and outcomes -- Socioeconomic aspects of systemic lupus erythematosus -- Biomarkers in systemic lupus erythematosus -- Overview of the pathogenesis of systemic lupus erythematosus -- Systemic lupus erythematosus and the environment -- Genes and genetics in human systemic lupus erythematosus -- Hormones -- The complement system in systemic lupus erythematosus -- T cells -- Integrating current thinking on peripheral B-celltolerance in lupus -- Neutrophils in systemic lupus erythematosus -- The role of dendritic cells in systemic lupus erythematosus -- Cytokines -- Toll-like receptors, systemic lupus erythematosus -- The interferon system in lupus erythematosus -- Humoral pathogenesis : Fc[gamma] receptors in autoimmunity and end-organ damage -- Apoptosis, autophagy, and necrosis -- Infections in early systemic lupus erythematosus pathogenesis -- Origin of autoantibodies -- Anti-DNA antibodies -- Antihistone and antispliceosome antibodies -- Immune complexes in systemic lupus erythematosus -- Microrna in systemic lupus erythematosus -- Oxidative stress in systemic lupus erythematosus : causes, consequences, and treatment -- Reactive nitrogen intermediates in the pathogenesis of systemic lupus erythematosus -- Epigenetics -- What do mouse models teach us about human systemic lupus erythematosus? -- Genes and genetics of murine systemic lupus erythematosus -- Mechanisms of renal damage in systemic lupus erythematosus -- Mechanisms of vascular damage in systemic lupus erythematosus -- The mechanism of skin damage -- Pathogenesis of tissue injury in the brain in patients with systemic lupus erythematosus -- Constitutional symptoms and fatigue in systemic lupus erythematosus -- The musculoskeletal system in systemic lupus erythematosus -- Cutaneous lupus erythematosus -- The clinical evaluation of kidney disease in systemic lupus erythematosus -- The pathology of lupus nephritis -- Cardiovascular disease in systemic lupus erythematosus -- The lung in systemic lupus erythematosus -- Gastrointestinal, hepatic, and pancreatic disorders in systemic lupus erythematosus -- Systemic lupus erythematosus and infections -- Malignancies in systemic lupus erythematosus -- The nervous system in systemic lupus erythematosus -- Overlap syndromes -- Systemic lupus erythematosus and the eye -- Pregnancy and fertility in systemic lupus erythematosus -- Neonatal lupus : clinical spectrum, biomarkers, pathogenesis, and approach to treatment -- Incomplete lupus -- Childhood-onset systemic lupus erythematosus -- Drug-induced lupus -- Vasculitis in lupus -- Pathogenesis of antiphospholipid syndrome -- Antibodies and diagnostic tests in antiphospholipid syndrome -- Clinical manifestations -- Nonsteroidal anti-inflammatory drugs in systemic lupus erythematosus -- Value of antimalarial drugs in the treatment of lupus -- Systemic glucocorticoids -- Cytotoxic-immunosuppressive drug treatment -- Treatment of antiphospholipid syndrome -- New treatments for systemic lupus erythematosus -- Management lessons from clinical trials of kidney disease in systemic lupus erythematosus -- Repositioning drugs for systemic lupus erythematosus. 
588 0 |a Online resource; title from resource home page (ClinicalKey, viewed April 12, 2017). 
650 0 |a Systemic lupus erythematosus. 
650 0 |a Biochemical markers. 
650 0 |a Comorbidity. 
650 1 2 |a Lupus Erythematosus, Systemic  |x diagnosis  |0 (DNLM)D008180Q000175 
650 2 |a Lupus Erythematosus, Systemic  |0 (DNLM)D008180 
650 2 |a Multimorbidity  |0 (DNLM)D000076322 
650 2 2 |a Lupus Erythematosus, Systemic  |x physiopathology  |0 (DNLM)D008180Q000503 
650 2 2 |a Lupus Erythematosus, Systemic  |x therapy  |0 (DNLM)D008180Q000628 
650 2 2 |a Biomarkers  |0 (DNLM)D015415 
650 2 2 |a Comorbidity  |0 (DNLM)D015897 
650 6 |a Lupus �eryth�emateux diss�emin�e.  |0 (CaQQLa)201-0250523 
650 6 |a Marqueurs biologiques.  |0 (CaQQLa)201-0177920 
650 6 |a Comorbidit�e.  |0 (CaQQLa)201-0319011 
650 7 |a HEALTH & FITNESS  |x Diseases  |x General.  |2 bisacsh 
650 7 |a MEDICAL  |x Clinical Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Diseases.  |2 bisacsh 
650 7 |a MEDICAL  |x Evidence-Based Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Internal Medicine.  |2 bisacsh 
650 7 |a Comorbidity.  |2 fast  |0 (OCoLC)fst00871254 
650 7 |a Biochemical markers.  |2 fast  |0 (OCoLC)fst00831950 
650 7 |a Systemic lupus erythematosus.  |2 fast  |0 (OCoLC)fst01141443 
700 1 |a Tsokos, George C.,  |e editor. 
776 0 8 |i Print version:  |t Systemic lupus erythematosus.  |d London : Elsevier/Academic Press, [2016]  |z 9780128019177  |w (OCoLC)926743093 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780128019177  |z Texto completo