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Molecular nutrition and diabetes : a volume in the molecular nutrition series /
Molecular Nutrition and Diabetes: A Volume in the Molecular Nutrition Series focuses on diabetes as a nutritional problem and its important metabolic consequences. Fuel metabolism and dietary supply all influence the outcome of diabetes, but understanding the pathogenesis of the diabetic process is...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam :
Academic Press is an imprint of Elsevier,
2015.
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 020 | |a 9780128017616 |q (electronic bk.) | ||
| 020 | |a 0128017619 |q (electronic bk.) | ||
| 020 | |z 9780128015858 | ||
| 035 | |a (OCoLC)932016698 | ||
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| 072 | 7 | |a SCI |x 056000 |2 bisacsh | |
| 082 | 0 | 4 | |a 571.6 |2 23 |
| 245 | 0 | 0 | |a Molecular nutrition and diabetes : |b a volume in the molecular nutrition series / |c edited by Didac Mauricio. |
| 264 | 1 | |a Amsterdam : |b Academic Press is an imprint of Elsevier, |c 2015. | |
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 588 | 0 | |a Online resource; title from PDF title page (EBSCO, viewed January 4, 2016). | |
| 520 | |a Molecular Nutrition and Diabetes: A Volume in the Molecular Nutrition Series focuses on diabetes as a nutritional problem and its important metabolic consequences. Fuel metabolism and dietary supply all influence the outcome of diabetes, but understanding the pathogenesis of the diabetic process is a prelude to better nutritional control. Part One of the book provides general coverage of nutrition and diabetes in terms of dietary patterns, insulin resistance, and the glucose-insulin axis, while Part Two presents the molecular biology of diabetes and focuses on areas such as oxidative stress, mitochondrial function, insulin resistance, high-fat diets, nutriceuticals, and lipid accumulation. Final sections explore the genetic machinery behind diabetes and diabetic metabolism, including signaling pathways, gene expression, genome-wide association studies, and specific gene expression. While the main focus of each chapter is the basic and clinical research on diabetes as a nutritional problem, all chapters also end with a translational section on the implications for the nutritional control of diabetes. | ||
| 505 | 0 | |a Front Cover -- Series Preface -- MOLECULAR NUTRITION AND DIABETES -- Copyright -- Dedication -- Contents -- Contributors -- Preface -- Acknowledgments -- 1 -- GENERAL AND INTRODUCTORY ASPECTS -- 1 -- Nutrition and Diabetes: General Aspects -- 1. INTRODUCTION -- 2. HISTORICAL PERSPECTIVE -- 3. GUIDELINES -- 3.1 Caloric Intake -- 3.2 Carbohydrate -- 3.3 Fat -- 3.4 Protein -- 3.5 Sweeteners -- 3.6 Supplements -- 3.7 Sodium Intake -- 3.8 Translation into Food Intake -- 4. EVIDENCE FROM CLINICAL TRIALS -- 4.1 Macronutrient Composition -- 4.1.1 Protein Content. | |
| 505 | 8 | |a 4.1.1.1 Protein Intake in Diabetic Kidney Disease -- 4.1.2 Carbohydrate Content and Quality -- 4.1.2.1 Low GI -- 4.1.3 Fat Content -- 4.1.4 Summary -- 4.2 Supplements -- 4.2.1 Herbal Products -- 4.2.2 Whole Grains -- 4.2.3 Omega-3 Fatty Acids -- 4.2.4 Nuts -- 4.3 Micronutrients -- 4.4 Eating Patterns -- 4.4.1 Mediterranean (MED) Style -- 4.4.2 Vegetarian and Vegan -- 4.4.3 Dietary Approaches to Stop Hypertension (DASH) -- 4.5 Carbohydrate Counting in T1D -- 5. FURTHER RESEARCH -- 6. CONCLUSIONS -- References -- 2 -- Dietary Patterns and Insulin Resistance -- 1. INTRODUCTION -- 2. CARBOHYDRATES. | |
| 505 | 8 | |a 3. LIPIDS -- 4. PROTEINS -- 5. CONCLUDING REMARKS -- References -- 3 -- (Sb (B-Cell Metabolism, Insulin Production and Secretion: Metabolic Failure Resulting in Diabetes -- 1. INTRODUCTION TO PANCREATIC (Sb (B-CELL METABOLISM AND METABOLIC LINKS TO INSULIN SECRETION -- 2. THE ROLE OF GLUCOSE METABOLISM, FATTY ACID METABOLISM, AND AMINO ACID METABOLISM IN THE GENERATION OF METABOLIC STIMULUS-SECRETION COUPLING FACTORS -- 2.1 Glucose Metabolism and Insulin Secretion -- 2.1.1 Glucose Transporters and Glucokinase -- 2.1.2 The First Phase of Insulin Secretion Is KATP+ Channel-Dependent. | |
| 505 | 8 | |a 2.1.3 The Second Phase of Chronic Insulin Secretion Is KATP+ Independent -- 2.2 Fatty Acid Metabolism and Insulin Secretion -- 2.2.1 Free Fatty Acids and (Sb (B Cells -- 2.2.2 (Sb (B oxidation of FFAs in (Sb (B-Cell Mitochondria -- 2.2.3 A Critical Shift in FFA Metabolism Occurs after Glucose Influx: The "Trident Model" Hypothesis -- 2.2.3.1 TCA/Malonyl-CoA Metabolic Signaling -- 2.2.3.2 Glycerolipid/Fatty Acid Cycling -- 2.2.3.3 G Protein-Coupled Receptor -- 2.3 Amino Acid Metabolism and Insulin Secretion -- 3. NUTRIENT REGULATION OF (Sb (B-CELL GENE EXPRESSION. | |
| 505 | 8 | |a 4. METABOLIC FAILURE IN (Sb (B-CELL DYSFUNCTION AND ONSET OF DIABETES -- 4.1 A Brief Introduction to Type 1 and Type 2 Diabetes -- 4.2 Glucotoxicity -- 4.3 (Sb (B-Cell Exhaustion -- 4.4 Reactive Oxygen Species -- 4.5 Maturity Onset Diabetes of the Young -- 4.6 Lipotoxicity -- 4.6.1 Lipotoxicity is Dependent on Lipid Structure and Exposure Time -- 4.6.2 Reactive Oxygen Species -- 4.7 ER Stress -- 5. THE CROSS-TALK OF APOPTOSIS WITH ROS AND ER STRESS IN (Sb (B-CELL DYSFUNCTION -- 6. CONCLUDING REMARKS -- References -- 4 -- Diet-Gene Interactions in the Development of Diabetes. | |
| 650 | 0 | |a Nutrient interactions. | |
| 650 | 0 | |a Diabetes |x Nutritional aspects. | |
| 650 | 0 | |a Molecular biology. | |
| 650 | 6 | |a Nutriments |x Interaction. |0 (CaQQLa)201-0188534 | |
| 650 | 6 | |a Diab�ete |x Aspect nutritionnel. |0 (CaQQLa)201-0066196 | |
| 650 | 6 | |a Biologie mol�eculaire. |0 (CaQQLa)201-0064024 | |
| 650 | 7 | |a molecular biology. |2 aat |0 (CStmoGRI)aat300054470 | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Anatomy & Physiology. |2 bisacsh | |
| 650 | 7 | |a Diabetes |x Nutritional aspects |2 fast |0 (OCoLC)fst00892176 | |
| 650 | 7 | |a Molecular biology |2 fast |0 (OCoLC)fst01024734 | |
| 650 | 7 | |a Nutrient interactions |2 fast |0 (OCoLC)fst01042182 | |
| 700 | 1 | |a Mauricio, Didac, |e editor. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780128015858 |z Texto completo |