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A historical perspective on evidence-based immunology /
A Historical Perspective on Evidence-Based Immunology focuses on the results of hypothesis-driven, controlled scientific experiments that have led to the current understanding of immunological principles. The text helps beginning students in biomedical disciplines understand the basis of immunologic...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam, Netherlands :
Elsevier,
[2016]
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Dedication; A HISTORICAL PERSPECTIVE ON EVIDENCE-BASED IMMUNOLOGY; Copyright; Contents; Foreword; Glossary of Historical Terms; 1
- Innate Host Defense Mechanisms and Adaptive Immun; INTRODUCTION; INNATE DEFENSE MECHANISMS; Anatomy; Cells of the Innate Host Defenses; Antimicrobial Molecules; Effector Mechanisms; Inflammation; Phagocytosis; Complement; NK Lymphocyte-mediated Cytotoxicity; Recognition of Pathogens; ADAPTIVE IMMUNE RESPONSES; Anatomy; Lymphocytes of the Adaptive Immune/ esponse; Effector Mechanisms; Recognition of Pathogens; CONCLUSION; References; TIME LINE.
- 2
- Hallmarks of the Adaptive Immune ResponsesINTRODUCTION; IMMUNOLOGIC SPECIFICITY; Specificity of the Adaptive Immune Response to/ iological Pathogens; Specificity of the Response to Synthetic Pathogens; SELF-NON-SELF-DISCRIMINATION; IMMUNOLOGIC MEMORY; Early Anecdotal Evidence; Smallpox Vaccination Comes to Western Medicine; Development of Other Vaccines; Mechanisms to Explain Immunologic Memory; Duration of Immunologic Memory; Cell Proliferation in Immunologic Memory; CONCLUSION; References; TIME LINE; 3
- Two Effector Mechanisms of the Adaptive Immune Response; INTRODUCTION; ANTIBODY.
- Development of SerotherapyEhrlich's Side-Chain Theory of Antibody Formation; CELL-MEDIATED IMMUNITY; Transfer of Skin Hypersensitivity Reactions; Transfer of Graft Rejection; CONCLUSION; References; TIME LINE; 4
- The Small Lymphocyte Is the Antigen Reactive Cell; INTRODUCTION; THE SMALL LYMPHOCYTE; PASSIVE TRANSFER EXPERIMENTS; MIGRATORY PATHWAYS OF SMALL LYMPHOCYTES; DEPLETION EXPERIMENTS; IMMUNOCOMPETENCE OF THORACIC DUCT LYMPHOCYTES; MORPHOLOGICAL CHANGES OF ACTIVATED SMALL/ YMPHOCYTES; CONCLUSION; References; TIME LINE; 5
- Lymphocytes Transform into Plasma Cells and Produce Antibodies.
- INTRODUCTIONCELLS AND ANTIBODIES; Composition of Antibodies; ANTIGENS AND ANTIBODIES IN/ YMPHOID ORGANS; LYMPHOCYTE-PLASMA CELL DEBATE; PASSIVE TRANSFER STUDIES; VISUALIZATION OF ANTIBODY-FORMING CELLS; Observations Using Immunofluorescent Stains; TRANSFORMATION OF SMALL LYMPHOCYTES INTO/ LASMA CELLS; CONCLUSION; References; TIME LINE; 6
- The Clonal Selection Theory of Antibody Formation; INTRODUCTION; EARLY MODELS OF ANTIBODY FORMATION; CHALLENGES TO INSTRUCTION MODELS; PARADIGM SHIFT: FROM INSTRUCTION TO SELECTION; The Modified Enzyme Concept.
- The Natural Selection Hypothesis of/ ntibody FormationTHE CLONAL SELECTION THEORY; An Attempt to Disprove the Clonal Selection Theory; Extension of the Clonal Selection Theory to/ Lymphocytes; CONCLUSION; References; TIME LINE; 7
- Plasma Cells Produce Antibody of a Single Specificity; INTRODUCTION; SINGLE CELL EXPERIMENTS: DEVELOPMENT OF THE/ ICRODROP TECHNIQUE; IMMUNOFLUORESCENT STUDIES; ANTIGEN RECEPTORS ON B LYMPHOCYTES; Cell Surface Immunoglobulin and Secreted Antibody Possess the Same Specificity; MULTIPLE MYELOMA AND THE ONE CELL: ONE/ NTIBODY CONCEPT.