Current and Emerging Technologies for the Diagnosis of Microbial Infections /
In this book the latest volume of series, provides comprehensive, cutting-edge reviews of current and emerging technologies in the field of clinical microbiology. The book features a wide variety of state-of-the art methods and techniques for the diagnosis and management of microbial infections, wit...
Clasificación: | Libro Electrónico |
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Otros Autores: | , |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
London :
Academic Press,
2015.
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Colección: | Methods in microbiology ;
v. 42. |
Temas: | |
Acceso en línea: | Texto completo Texto completo |
Tabla de Contenidos:
- Front Cover; Current and Emerging Technologies for the Diagnosis of Microbial Infections; Copyright; Contents; Contributors; Preface; Chapter 1: Total Laboratory Automation in Clinical Bacteriology; 1. Clinical Bacteriology and Automation: background; 2. Specimen Collection: liquid Microbiology; 3. Pre-analytical Automation; 4. Pre-analytical Bacteriology Specimen Plating Instruments; 4.1. Isoplater; 4.2. Innova; 4.3. BD Kiestra InoqulA+; 4.4. Previ Isola; 4.5. Copan WASP; 4.6. Prelude: i2a; 4.7. deltalab AUTOPLAK; 5. Digital Plate Reading; 6. TLA Systems; 6.1. BD Kiestra; 6.2. Copan WASPLab.
- 6.3. i2a: ECITALS7. Change Management: A Holistic Approach to Automation in Bacteriology; References; Chapter 2: MALDI-TOF Mass Spectrometry for Microorganism Identification; 1. Introduction; 1.1. MALDI-TOF MS: Principles and Processes; 1.2. Commercially Available MALDI-TOF MS Platforms; 1.3. Factors Influencing the Performance of MALDI-TOF MS; 2. Microbial Identification by MALDI-TOF MS; 2.1. Comparison of MALDI-TOF MS and Conventional Methods for the Identification of Routine Isolates; 2.2. Comparison of Commercially Available MALDI-TOF MS Systems.
- 2.3. Laboratory Cost Savings Associated with Using MALDI-TOF MS for Isolate Identification3. Performance of MALDI-TOF MS for the Identification of Routine Clinical Isolates; 3.1. Identification of Gram-Positive Bacteria; 3.2. Identification of Gram-Negative Bacteria; 3.3. Identification of Anaerobes; 3.4. Identification of Mycobacteria; 3.5. Identification of Yeast; 3.6. Identification of Filamentous Fungi; 3.7. Identification of Select Agents; 4. Direct Identification from Clinical Specimens; 4.1. Identification of Microorganisms Directly from Positive Blood Cultures.
- 4.2. Identification of Bacteria Directly from Urine Specimens4.3. Identification of Bacteria Directly from Cerebrospinal Fluid; Limitations and Conclusions; References; Chapter 3: POC Tests in Microbial Diagnostics: Current Status; 1. Introduction; 2. The Current Utilisation of Infectious Diseases POC Testing; 2.1. Viral Respiratory Infections; 2.2. HIV/AIDS, Tuberculosis, Sexually Transmitted Infections; 2.3. Diarrhoea and Gastrointestinal Diseases; 2.4. Surveillance, Prevention, and Diagnosis of Healthcare-Acquired Infections.
- 2.5. Anticipated POC Testing Advances Through Biomarkers or Improved Technologies2.5.1. Sepsis; 2.5.2. Technological advances in rapid immunochromatographic platforms; 2.5.3. Paper-based diagnostics; 2.6. Patient Empowerment Is Key for Any POC Test; 3. The Road to POC Molecular Diagnostics Is Paved with Good Intentions and Technologies; 3.1. Near-POC Testing; 3.2. Isothermal Amplification Technologies; 3.3. Integrated Molecular Diagnostics Platforms; 3.3.1. The GeneXpert� platform; 3.3.2. The GenePOC platform; Conclusions; Acknowledgements; References.