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Molecular and cellular regulation of adaptation to exercise /
Molecular Aspects of Exercise Biology and Exercise Genomics, the latest volume in the Progress in Molecular Biology and Translational Science series includes a comprehensive summary of the evidence accumulated thus far on the molecular and cellular regulation of the various adaptations taking place...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Waltham, MA :
Academic Press is an imprint of Elsevier,
2015.
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| Colección: | Progress in molecular biology and translational science ;
volume 135. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
Tabla de Contenidos:
- Front Cover; Molecular and Cellular Regulation of Adaptation to Exercise; Copyright; Contents; Contributors; Preface; Chapter One: Adaptation to Acute and Regular Exercise: From Reductionist Approaches to Integrative Biology; 1. Introduction; 2. Sedentary Time, Physical Activity, and Fitness; 3. Reductionism, Systems Biology, and Integrative Physiology; 4. Genomic and ENCODE Facts: A Gold Mine for Exercise Biology; 5. About the Content of the Volume; 6. Summary and Conclusions; References; Chapter Two: Exercise and Regulation of Carbohydrate Metabolism; 1. Introduction
- 2. Carbohydrate Utilization During Rest and Exercise3. Muscle Glycogen; 4. Glucose Transport; 5. Exercise Signals Regulating Glucose Transport; 5.1. AMPK and LKB1; 5.2. Ca2+/Calmodulin-Dependent Protein Kinases; 5.3. Downstream Signals Mediating Exercise-Stimulated Glucose Transport; 5.4. AS160 and TBC1D1; 6. Increases in Insulin Sensitivity for Glucose Transport After Exercise; 7. Exercise Training: Impact on Healthy People and People with Type 2 Diabetes; Acknowledgments; References; Chapter Three: Exercise and Regulation of Lipid Metabolism; 1. Crossover Concept
- 2. Fat Metabolism During Exercise2.1. Overview of Whole-Body Fat Oxidation During Exercise; 2.2. Adipose-Derived Free Fatty Acid Utilization During Exercise; 2.2.1. Adipose Tissue Lipolysis and Fatty Acid Utilization by Skeletal Muscle; 2.2.2. Fatty Acid Transporters; 2.3. Very-Low-Density Lipoprotein Triglyceride Utilization During Exercise; 2.4. IMTG Utilization During Exercise; 2.4.1. Contribution of IMTG to Exercise Substrate Metabolism; 2.4.2. Skeletal Muscle Lipases; 2.5. Regulation of Mitochondrial Fatty Acid Oxidation; 2.5.1. Regulation of Long-Chain Acyl-CoA Synthetase
- 2.5.2. Regulation of Carnitine Palmitoyltransferase-1-Malonyl-CoA2.5.3. Regulation of CPT-1-Carnitine Provision; 3. Postexercise Lipid Metabolism; 3.1. Lipid Dynamics During Exercise; 3.2. Excess Postexercise Oxygen Consumption; 3.2.1. EPOC and Exercise Duration; 3.2.2. EPOC and Exercise Intensity; 3.2.3. EPOC and Exercise Modality; 4. Dietary Factors Influencing Exercise Fat Metabolism; 4.1. Carbohydrate Loading; 4.2. Ketogenic Diet (Low-Carbohydrate, High-Fat); 4.3. Dietary Considerations in the Postexercise Period; 5. Molecular Programming of Lipid Metabolism; 5.1. PPAR-Alpha
- 5.2. PPAR-Delta5.3. PPAR-Gamma; 6. Concluding Remarks; References; Chapter Four: Exercise and Regulation of Protein Metabolism; 1. Introduction; 1.1. What Techniques Have Informed Us upon How Exercise Impacts Muscle Protein Metabolism?; 2. The Regulation of Protein Metabolism by Exercise; 2.1. RE-T and Muscle Protein Metabolism; 2.2. EE-T and Muscle Protein Metabolism; 3. Signal Transduction Regulating Muscle Protein Metabolism Responses to Exercise; 4. Conclusions; References; Chapter Five: Exercise and the Regulation of Mitochondrial Turnover; 1. Introduction