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Genetic control of malaria and dengue /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Adelman, Zach N. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Academic Press is an imprint of Elsevier, [2015]
Temas:
Acceso en línea:Texto completo

MARC

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020 |z 9780128002469 
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245 0 0 |a Genetic control of malaria and dengue /  |c edited by Zach N. Adelman. 
264 1 |a London :  |b Academic Press is an imprint of Elsevier,  |c [2015] 
264 4 |c �2016 
300 |a 1 online resource 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
500 |a Includes index. 
588 0 |a Online resource; title from PDF title page (ScienceDirect, viewed October 28, 2015). 
505 0 |a Front Cover -- Genetic Control of Malaria and Dengue -- Copyright Page -- Contents -- List of Contributors -- Biography -- Chapter 1 -- Chapter 2 -- Chapter 3 -- Chapter 4 -- Chapter 5 -- Chapter 6 -- Chapter 7 -- Chapters 8, 13 -- Chapter 9 -- Chapter 10 -- Chapter 11 -- Chapter 12 -- Chapter 14 -- Chapter 15 -- Chapter 16 -- Chapter 17 -- Chapter 18 -- Chapter 19 -- 1 Transgenic Pests and Human Health: A Short Overview of Social, Cultural, and Scientific Considerations -- Introduction -- Current State of GMOs -- Dengue Fever and Malaria -- Dengue Fever -- Malaria -- Dengue and Malaria Control -- Things to Consider Before Implementing GMO Control Methods -- Allocating Resources Between Treatment and Control -- Economic Development -- Community Engagement -- Values and Ethics of Control Measures -- Stewardship -- Animal Welfare -- Justice As Fairness -- Precaution -- An Ethical, Cultural, and Social Framework -- Regulation, Deliberation, and Public Communication of Biotechnology -- Current US Regulation of Biotechnology -- Biotechnology and the Public Sphere -- Models of Public Communication -- Public Opinion of Transgenics -- Conclusions -- Acknowledgments -- References -- 2 Concept and History of Genetic Control -- Introduction -- Agricultural Applications of Genetic Control Lead the Field -- Eradication of the New World Screwworm Fly Cochliomyia hominivorax Using the Sterile Insect Technique -- Use of Genetic Sexing Strains in Mediterranean Fruit Fly SIT Programs -- The Australian Sheep Blowfly (Lucilia cuprina) Field Female Killing Strains -- The Current State of Using SIT to Control Agricultural Pests -- Attempts to Extend Genetic Control to Mosquitoes -- Progress Without Modern Biotechnology -- Cytoplasmic Incompatibility and Wolbachia Population Replacement -- Classical SIT -- Chromosome Rearrangements. 
505 8 |a Population Replacement Without Transgenesis -- Modern Biotechnology Attempts to Cover the Achilles Heel of Mosquito SIT -- Increasing Suppression Leveraging Larval Competition -- Paratransgenesis Using Transgenic Symbionts -- Population Replacement with Factors Detrimental to Mosquitoes -- Population Replacement with Beneficial Factors -- Acknowledgments -- References -- 3 Considerations for Disrupting Malaria Transmission in Africa Using Genetically Modified Mosquitoes, Ecology of Anopheline... -- Malaria in Africa: Current Situation -- Malaria Vectors in the African Region -- Malaria Parasites and Their Public Health Significance -- Current Approaches for Malaria Vector Control -- Biological and Ecological Considerations for GM Release and Monitoring -- Operational Considerations and Capacity Building in Africa -- References -- 4 Ecology of Malaria Vectors and Current (Nongenetic) Methods of Control in the Asia Region -- Malaria Risk in the South East Asia Region -- Ecology of Common Malaria Vectors -- Anopheles culicifacies -- Anopheles fluviatilis -- Anopheles stephensi -- Anopheles dirus -- Anopheles minimus -- Current (Nongenetic) Methods of Vector Control -- Indoor Residual Spraying -- Long-Lasting Insecticide-Treated Nets -- Source Reduction -- Integrated Vector Management -- Progress of (Nongenetic) Vector Control in the Asia Region -- Evidence of Success -- Evidence of Resistance to Insecticides -- Key Challenges -- Insecticide Resistance Monitoring -- Outdoor Biting -- Behavioral Changes of Vectors -- Conclusions -- References -- 5 Ecology of Anopheles darlingi, the Primary Malaria Vector in the Americas and Current Nongenetic Methods of Vector Control -- Introduction -- Ecology of Anopheles darlingi -- Larvae -- Adult Behavior -- Anopheles albimanus and Anopheles aquasalis: Regionally Important Vectors -- Colonization. 
505 8 |a Coevolution of Anopheles and Plasmodium -- Current Control of Anopheles darlingi -- Adult Stage -- Larval Stage -- Scenarios Post Local Elimination of Anopheles darlingi -- Conclusions -- Acknowledgments -- References -- 6 Considerations for Disrupting Dengue Virus Transmission -- Ecology of Aedes aegypti and Current (Nongenetic) Methods of Control -- Current Burden of Dengue -- Causes of Widespread Dengue Transmission -- Major Dengue Vectors Worldwide -- How Does the Ecology of Aedes aegypti Complicate Control Efforts? -- Domestication -- Density-Dependent Population Regulation -- Spatial Heterogeneity and Super-Producer Aquatic Habitats of Aedes aegypti -- Cryptic Aquatic Habitats -- Egg Quiescence -- Population Dynamics of Aedes aegypti and Dengue -- Main Current Limitations to Control Dengue -- Current Interventions to Control Mosquito Vectors -- Improving Mosquito Control -- Local Aedes Populations Should be Managed in Space and Time Using an Area-Wide Approach -- Effective Control Agent -- Efficient Delivery System of the Control Agent -- Sufficient Coverage -- Evaluation of Impact -- Perspectives of Success Using Genetically Modified Mosquitoes to Control Dengue Vectors -- Self-Limiting Population Suppression -- Self-Sustaining Vector Population Replacement -- References -- 7 The Challenge of Disrupting Vectorial Capacity -- Purpose -- Strategy: How Do We Use the Vector to Achieve Reductions in Parasite Transmission? -- Lessons Learnt? -- Effective Delivery -- Maintenance of the Quality of the Intervention -- Sustaining Effective Delivery -- Polyvalent Intervention -- GM Interventions: How Do We Manage the Expectations and Measure Impact -- Managing Expectation -- Measuring Impact -- References -- 8 Gene Insertion and Deletion in Mosquitoes -- Random Insertion of Genetic Elements -- Transposons -- Docking-Site-Based Integration. 
505 8 |a Other Recombinases -- Site-Specific Nucleases -- Homing Endonucleases -- Chimeric Nucleases (ZFNs and TALENs) -- CRISPR/Cas9 -- Targeted Insertion of Genetic Elements Through Homologous Recombination -- Controlling Transgene Expression -- the Current State of the Mosquito Toolbox -- Promoters -- Identifying New Promoters, a Cautionary Tale -- Bipartite Tet Systems -- Other Bipartite Expression Systems -- Considerations and Outlook -- References -- 9 Gene Drive Strategies for Population Replacement -- Introduction -- Early Inspiration -- Promising New Systems -- Design Criteria -- Gene Drive Systems That Spread Via Target Site Cleavage and Repair -- Transposable Elements -- Homing Endonuclease Genes -- TALENs and ZFNs -- Clustered, Regularly Interspaced, Short Palindromic Repeats -- Toxin-Antidote Gene Drive Systems -- Medea -- Toxin-Antidote-Based Underdominance -- Killer-Rescue -- Other Confineable Toxin-Antidote Systems -- Translocations -- Conclusion -- Gene Drive for Any Situation -- Outstanding Issues and Future Outlook -- Acknowledgments -- References -- 10 Exploring the Sex-Determination Pathway for Control of Mosquito-Borne Infectious Diseases -- Introduction -- Current Genetic Methods and Strategies -- Sterile Insect Technique -- Incompatible Insect Technique -- Release of Insects Carrying a Dominant Lethal Gene -- A Sex Ratio Distorter in Aedes aegypti and a Synthetic Sex Ratio Distorter in Anopheles gambiae -- Sex Separation -- Self-Sustaining Population Replacement Strategies -- Sex Determination in Mosquitoes -- M Locus and the Y Chromosome -- Doublesex (dsx), Fruitless (fru), and the Elusive Transformer (tra) -- Dosage Compensation and Sex Determination -- Toward the Discovery of the M Factor and Tra -- Ways and Considerations to Explore the Sex-Determination Pathway for Control -- Targets and Sex-Specific Reagents. 
505 8 |a Sex Conversion Versus Female Lethality -- Timing of the Transgene Effect -- Conditional Expression -- "Driving Maleness" to Control Mosquito-Borne Infectious Diseases -- Acknowledgments -- References -- 11 Disruption of Mosquito Olfaction -- Introduction -- Anatomy of the Mosquito Olfactory System -- Chemosensory Receptors Detecting Odorants and CO2 in Drosophila and Mosquitoes -- Odorant Receptors -- Ionotropic Receptors -- Gustatory Receptors -- Use of Genome-Editing Technology to Decode Mosquito Attraction to Humans -- Targeted Mutagenesis of OR-Mediated Odorant Reception -- Targeted Mutagenesis of CO2 Reception -- Proposed Genetic Strategies Targeting Mosquito Olfaction -- Next-Generation Chemical Strategies Targeting Mosquito Olfaction -- Conclusions -- Acknowledgments -- References -- 12 Disruption of Mosquito Blood Meal Protein Metabolism -- Introduction: An Overview of Blood Meal Protein Metabolism in Mosquitoes -- Exploring Blood Meal Protein Amino Acid Carbon Skeletons Using Radioactive Isotopes -- Dynamics of Blood Meal Protein Amino Acid Metabolism -- Fate of Blood Meal Amino Acids at the End of the Gonotrophic Cycle and Utilization of Maternal Energy Reserves During a Gon... -- Investigating Blood Meal Protein Amino Acid Nitrogen Using Traditional and Modern Approaches -- Fate of Nitrogen Derived from Deamination of Amino Acids Using Classical Biochemical and Molecular Techniques -- Fate of Nitrogen Derived from Deamination of Amino Acids Using Isotopically-Labeled 15N-Compounds, Mass Spectrometry, and R... -- Fixation and Assimilation of Ammonia -- Excretion of Nitrogen Waste Products -- Conclusions and Future Directions -- Acknowledgments -- References -- 13 Engineering Pathogen Resistance in Mosquitoes -- Malaria and Dengue -- Malaria -- Dengue -- Engineering Resistance to Pathogens -- Pathogen-Derived Resistance (RNAi). 
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650 0 |a Dengue  |x Prevention. 
650 0 |a Genetic engineering. 
650 0 |a Mosquitoes. 
650 0 |a Malaria. 
650 0 |a Dengue. 
650 0 |a Insects as carriers of disease. 
650 0 |a Arbovirus infections. 
650 0 |a Protozoan diseases. 
650 0 |a Arthropod vectors. 
650 0 |a Diptera. 
650 0 |a Hemorrhagic fever. 
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650 0 |a Insects. 
650 0 |a Virus diseases. 
650 0 |a Diseases. 
650 0 |a Arthropoda. 
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650 0 |a Public health. 
650 0 |a Medical care. 
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700 1 |a Adelman, Zach N.,  |e editor. 
776 0 8 |i Print version:  |a Adelman, Zach N.  |t Genetic Control of Malaria and Dengue.  |d Saint Louis : Elsevier Science, �2015 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780128002469  |z Texto completo