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Virus as populations : composition, complexity, dynamics, and biological implications /
Virus as Populations: Composition, Complexity, Dynamics, and Biological Implications explains fundamental concepts that arise from regarding viruses as complex populations when replicating in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capaci...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam :
Elsevier Ltd.,
[2016]
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 001 | SCIDIR_ocn922581506 | ||
| 003 | OCoLC | ||
| 005 | 20231120112025.0 | ||
| 006 | m o d | ||
| 007 | cr cnu|||unuuu | ||
| 008 | 150930s2016 ne ob 001 0 eng d | ||
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| 020 | |a 9780128009949 |q (electronic bk.) | ||
| 020 | |a 0128009942 |q (electronic bk.) | ||
| 020 | |z 0128008377 | ||
| 020 | |z 9780128008379 | ||
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| 050 | 4 | |a QR360 | |
| 060 | 4 | |a QW 160 | |
| 072 | 7 | |a SCI |x 008000 |2 bisacsh | |
| 072 | 7 | |a SCI |x 045000 |2 bisacsh | |
| 082 | 0 | 4 | |a 579.2 |2 23 |
| 100 | 1 | |a Domingo, Esteban, |e author. | |
| 245 | 1 | 0 | |a Virus as populations : |b composition, complexity, dynamics, and biological implications / |c Esteban Domingo. |
| 264 | 1 | |a Amsterdam : |b Elsevier Ltd., |c [2016] | |
| 264 | 4 | |c �2016 | |
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file | ||
| 588 | 0 | |a Online resource; title from PDF title page (EBSCO, viewed October 2, 2015). | |
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a Introduction to virus origins and their role in biological evolution -- Molecular basis of genetic variation of viruses : error-prone replication -- Darwinian principles acting on highly mutable viruses -- Interaction of virus populations with their hosts -- Viral fitness as a measure of adaptation -- Virus population dynamics examined with experimental model systems -- Long-term virus evolution in nature -- Quasispecies dynamics in disease prevention and control -- Trends in antiviral strategies -- Collective population effects in nonviral systems. | |
| 520 | |a Virus as Populations: Composition, Complexity, Dynamics, and Biological Implications explains fundamental concepts that arise from regarding viruses as complex populations when replicating in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, probability to be transmitted or response to treatment, depend on virus population numbers and in the variations of such population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, new antiviral strategies such as lethal mutagenesis, and extensions of population heterogeneity to nonviral systems are included. These main concepts of the book are framed in recent observations on general virus diversity derived from metagenomic studies, and current views on the origin of viruses and the role of viruses in the evolution of the biosphere. Features current views on the key steps in the origin of life and origins of viruses Includes examples relating ancestral features of viruses with their current adaptive capacity Explains complex phenomena in an organized and coherent fashion that is easy to comprehend and enjoyable to read Considers quasispecies as a framework to understand virus adaptability and disease processes. | ||
| 650 | 0 | |a Viruses. | |
| 650 | 0 | |a Virus diseases. | |
| 650 | 0 | |a Virology. | |
| 650 | 0 | |a Medical virology. | |
| 650 | 2 | |a Virus Physiological Phenomena |0 (DNLM)D018406 | |
| 650 | 2 | |a Microbiological Phenomena |0 (DNLM)D008827 | |
| 650 | 2 | |a Phenomena and Processes | |
| 650 | 2 | |a Viruses |0 (DNLM)D014780 | |
| 650 | 2 | |a Virus Diseases |0 (DNLM)D014777 | |
| 650 | 2 | |a Virology |0 (DNLM)D014773 | |
| 650 | 6 | |a Virus. |0 (CaQQLa)201-0078047 | |
| 650 | 6 | |a Maladies �a virus. |0 (CaQQLa)201-0012316 | |
| 650 | 6 | |a Virologie. |0 (CaQQLa)201-0008933 | |
| 650 | 6 | |a Virologie m�edicale. |0 (CaQQLa)201-0168582 | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Biology. |2 bisacsh | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Microbiology. |2 bisacsh | |
| 650 | 7 | |a Medical virology |2 fast |0 (OCoLC)fst01014785 | |
| 650 | 7 | |a Virology |2 fast |0 (OCoLC)fst01167670 | |
| 650 | 7 | |a Virus diseases |2 fast |0 (OCoLC)fst01167739 | |
| 650 | 7 | |a Viruses |2 fast |0 (OCoLC)fst01167771 | |
| 776 | 0 | 8 | |i Print version: |z 9780128008379 |w (OCoLC)911073621 |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780128008379 |z Texto completo |