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The enzymes. Volume 37, Mechanism of the anticancer effect of phytochemicals /

Volume 37 will provide details on the major chemical constituents of medicinal plants and their mechanism of action as the anticancer compounds. This special issue, in addition to the previous volume (volume 36 of the Enzyme series was on the topic of Natural Products and Cancer Signaling Targets: I...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Bathaie, S. Zahra (Editor ), Tamanoi, Fuyuhiko (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Waltham, MA : Academic Press is an imprint of Elsevier, 2015.
Edición:First edition.
Colección:Enzymes ; volume 37.
Temas:
Acceso en línea:Texto completo
Texto completo

MARC

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245 0 4 |a The enzymes.  |n Volume 37,  |p Mechanism of the anticancer effect of phytochemicals /  |c edited by S. Zahra Bathaie and Fuyuhiko Tamanoi. 
246 3 0 |a Mechanism of the anticancer effect of phytochemicals 
250 |a First edition. 
264 1 |a Waltham, MA :  |b Academic Press is an imprint of Elsevier,  |c 2015. 
300 |a 1 online resource (xiii, 262 pages) :  |b illustrations. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a The enzymes ;  |v volume 37 
504 |a Includes bibliographical references and indexes. 
588 0 |a Online resource; title from title details screen (ScienceDirect, viewed August 27, 2015). 
505 0 |a ""Front Cover""; ""Mechanism of the Anticancer Effect of Phytochemicals""; ""Copyright""; ""Contents""; ""Contributors""; ""Preface""; ""Chapter One: How Phytochemicals Prevent Chemical Carcinogens and/or Suppress Tumor Growth?""; ""1. Introduction""; ""2. Phytochemicals Application in Chemoprevention Strategies""; ""2.1. Blocking Initiation/Reversing Promotion""; ""2.2. Activating Phase II Detoxifying Enzymes""; ""2.3. Prooxidant/Antioxidant Activities""; ""2.4. Protection Against Radiation""; ""2.5. Alteration in Signaling Pathways""; ""2.6. Effect on Cell-Cell Adhesion Machinery"" 
505 8 |a ""2.7. Induction of Epigenetic Changes""""3. Phytochemicals Usage as Chemotherapeutic""; ""3.1. Inhibition of Enzymes""; ""3.1.1. Inhibition of Topoisomerases I or II""; ""3.1.2. Effect on Telomerase""; ""3.1.3. Other Enzymes""; ""3.2. Direct Binding to Biomacromolecules""; ""3.3. Epigenetic Alteration/Chromatin Modification""; ""3.3.1. Histone Modifications: Acetylation/Deacetylation and Methylation/Demethylation""; ""3.3.2. DNA Methylation Status""; ""3.4. RNA Modulation""; ""3.5. Autophagy and UPR68""; ""3.6. Apoptosis Induction""; ""3.7. Cell Cycle Arrest"" 
505 8 |a ""3.8. Inhibiting Angiogenesis""""3.9. Adjuvant/Combinatorial Therapy""; ""4. Summary""; ""References""; ""Chapter Two: Quercetin and Tryptanthrin: Two Broad Spectrum Anticancer Agents for Future Chemotherapeutic Interventions""; ""1. Introduction""; ""2. Quercetin""; ""2.1. Source""; ""2.2. Biosynthesis""; ""2.3. Structure and Antioxidative Property""; ""2.4. Properties""; ""2.4.1. Antioxidant Property""; ""2.4.2. Free Radical Scavenging Activity""; ""2.4.3. Nitric Oxide Inhibitory Action""; ""2.4.4. Inhibition of Xanthine Oxidase""; ""2.4.5. Interaction with Other Enzyme Systems"" 
505 8 |a ""2.5. Pharmacokinetics""""2.6. Role as an Anticancer Agent""; ""2.6.1. Cell Cycle Regulation""; ""2.6.2. Quercetin�A?s Effect on Apoptosis""; ""2.6.3. Inhibition of Pathways Involved in Tumor Growth and Invasiveness""; ""2.7. Quercetin�A?s Role as an Anti-Inflammatory Agent""; ""2.8. Quercetin�A?s Influence on p53""; ""2.9. Quercetin�A?s Nontoxicity Against Normal Cells""; ""2.10. Quercetin�A?s Action Against Chemical-Induced Tumor and Xenograft""; ""2.11. Synergism with Other Drugs""; ""2.12. Clinical Study""; ""3. Tryptanthrin""; ""3.1. Chemistry""; ""3.2. Source""; ""3.3. Medicinal Value"" 
505 8 |a ""3.4. Cytotoxic and Anticancer Properties of Tryptanthrin""""3.5. Structural Modification of Tryptanthrin for Increasing its Bioactivity""; ""3.6. Tryptanthrin Prevents Development of Cancer by the Inhibition of Various Molecular Events""; ""3.6.1. Antioxidant Activity""; ""3.6.2. Anti-Inflammatory Activity""; ""3.7. Angiogenesis""; ""3.8. Toxicological Analysis""; ""4. Conclusion""; ""Acknowledgement""; ""References""; ""Chapter Three: Potential Anticancer Properties and Mechanisms of Action of Withanolides""; ""1. Introduction""; ""2. Reactive Oxygen Species Signaling"" 
520 |a Volume 37 will provide details on the major chemical constituents of medicinal plants and their mechanism of action as the anticancer compounds. This special issue, in addition to the previous volume (volume 36 of the Enzyme series was on the topic of Natural Products and Cancer Signaling Targets: Isoprenoids, Polyphenols and Flavonoids), will highlight the significant advance made in the field in elucidating mechanisms of anticancer effect of the major phytochemicals. Key features: * Contributions from leading authorities * Informs and updates on all the latest developments in the field. 
650 0 |a Phytochemicals  |x Therapeutic use. 
650 0 |a Phytochemicals  |x Molecular aspects. 
650 0 |a Antineoplastic agents. 
650 0 |a Phytonutrients. 
650 2 |a Phytochemicals  |0 (DNLM)D064209 
650 2 |a Antineoplastic Agents  |0 (DNLM)D000970 
650 6 |a Compos�es phytochimiques  |0 (CaQQLa)201-0325163  |x Emploi en th�erapeutique.  |0 (CaQQLa)201-0373975 
650 6 |a Anticanc�ereux.  |0 (CaQQLa)201-0004692 
650 6 |a Phytonutriments.  |0 (CaQQLa)000285517 
650 7 |a MEDICAL  |x Pharmacology.  |2 bisacsh 
650 7 |a Phytonutrients  |2 fast  |0 (OCoLC)fst01894964 
650 7 |a Antineoplastic agents  |2 fast  |0 (OCoLC)fst00810595 
650 7 |a Phytochemicals  |x Molecular aspects  |2 fast  |0 (OCoLC)fst01063237 
650 7 |a Phytochemicals  |x Therapeutic use  |2 fast  |0 (OCoLC)fst01063239 
700 1 |a Bathaie, S. Zahra,  |e editor. 
700 1 |a Tamanoi, Fuyuhiko,  |e editor. 
776 0 8 |i Print version:  |t Enzymes. Volume 37, Mechanism of the anticancer effect of phytochemicals.  |b First edition.  |d Waltham, MA : Academic Press is an imprint of Elsevier, 2015  |z 9780128038765  |z 0128038764  |w (OCoLC)911073512 
830 0 |a Enzymes ;  |v volume 37. 
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856 4 0 |u https://sciencedirect.uam.elogim.com/science/bookseries/18746047/37  |z Texto completo