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Stem cell and gene therapy for cardiovascular disease /
Stem Cell and Gene Therapy for Cardiovascular Disease is a state-of-the-art reference that combines, in one place, the breadth and depth of information available on the topic. As stem cell and gene therapies are the most cutting-edge therapies currently available for patients with heart failure, eac...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | , , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Waltham, MA :
Academic Press,
[2016]
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- ""Front Cover""; ""Stem Cell and Gene Therapy for Cardiovascular Disease""; ""Copyright Page""; ""Contents""; ""List of Contributors""; ""Preface""; ""Regenerative Medicine and the Cardiovascular System: A Good Start""; ""Gene Therapy""; ""Tissue Engineering""; ""Dedication""; ""Acknowledgments""; ""References""; ""I. Stem Cells""; ""1 Introduction and Overview of Stem Cells""; ""What is Regenerative Medicine?""; ""What Defines a Stem Cell?""; ""Types of Stem Cells""; ""Stem Cell Sources""; ""Bone Marrow""; ""Adipose Tissue""; ""Heart�a�?Cardiac Resident Progenitor Cells""
- ""Somatic (Skin) Cells""""Umbilical Cord and Placenta""; ""Endometrial Tissue""; ""Dental Pulp""; ""Other Classifications of Stem Cells""; ""Autologous versus Allogeneic Cells""; ""Multipotent Adult Progenitor Cells""; ""Cardiopoiesis-Derived MSCs""; ""Mechanisms of Action of Stem Cells""; ""Endogenous versus Exogenous Tissue Repair""; ""Functional Assays""; ""Sex Differences""; ""Safety Profile""; ""Summary""; ""References""; ""2 Pathological Assessment of Experimental Models of Stem Cell and Other Regenerative Therapies""; ""Introduction""; ""Preparation and Labeling""
- ""BrdU Incorporation""""Fluorescence Labeling and Dye Marking""; ""Nuclear Dyes""; ""Cytoplasmic Dyes""; ""Genetic Markers""; ""Endogenous Markers""; ""Exogenous Markers""; ""Delivery Routes for Stem Cells and Other Biological Agents""; ""Delivery Through the Vasculature""; ""Intramyocardial Delivery""; ""Pathologic Assessment""; ""Gross Examination""; ""Tissue Sampling""; ""Triphenyltetrazolium Chloride Staining for Infarct Size Quantification""; ""Microscopic Assessment""; ""General Evaluation""; ""Histologic Findings""; ""Cell Characterization""
- ""Angiogenesis and Capillary Density Assessment""""Conclusion""; ""References""; ""3 Large Animal Models for Cardiac Cell Therapy""; ""Introduction""; ""Is There a Need for Large Animal Models of Cardiac Diseases?""; ""Considerations when Selecting an Animal Model""; ""Animal Care: the Ideal is Not Always Easy""; ""Physiological Parameters and Data Collection""; ""Cardiovascular Anatomy""; ""Cardiovascular Physiology""; ""Models of Myocardial Ischemia""; ""Acute Myocardial Ischemia""; ""Coronary Ligation versus Coronary Balloon Occlusion""; ""Microsphere Embolization""
- ""Inorganic Mercury Thrombosis""""Thrombus""; ""Cryothermia""; ""Chronic Myocardial Ischemia""; ""Ameroid Constrictor""; ""Models of Overload""; ""Volume Overload""; ""Pressure Overload""; ""Models of DCM""; ""Models of Cardiotoxicity""; ""Cell Therapy""; ""Bone Marrow Harvest in Porcine Models""; ""Delivery of Cell Therapy""; ""Open Surgical Transmyocardial Injection""; ""Transcatheter Percutaneous Approach""; ""Intracoronary and Retrograde Delivery""; ""Transmyocardial Injection: Mapping and Injection""; ""Conclusions""; ""References""; ""I. Body�a�?s Native Repair Mechanisms""