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Handbook of the biology of aging /

Handbook of the Biology of Aging, Eighth Edition, provides readers with an update on the rapid progress in the research of aging. It is a comprehensive synthesis and review of the latest and most important advances and themes in modern biogerontology, and focuses on the trend of 'big data'...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Kaeberlein, Matt, 1971- (Editor ), Martin, George M., 1927- (editior.)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam : Elsevier Ltd., 2016.
Edición:Eighth edition.
Colección:Handbooks of aging ; v. 3.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • I. Basic Mechanisms of Aging: Models and Systems
  • 1 Longevity as a Complex Genetic Trait
  • 2 The mTOR Pathway and Aging
  • 3 Sirtuins, Healthspan, and Longevity in Mammals
  • 4 The Hypoxic Response and Aging
  • 5 The Role of Neurosensory Systems in the Modulation of Aging
  • 6 The Naked Mole-Rat: A Resilient Rodent Model of Aging, Longevity, and Healthspan
  • 7 Contributions of Telomere Biology to Human Age-Related Disease
  • 8 Systems Approaches to Understanding Aging
  • 9 Integrative Genomics of Aging
  • 10 NIA Interventions Testing Program: A Collaborative Approach for Investigating Interventions to Promote Healthy Aging
  • 11 Comparative Biology of Aging: Insights from Long-Lived Rodent Species
  • II. The Pathobiology of Human Aging
  • 12 Genetics of Human Aging
  • 13 The Aging Arterial Wall
  • 14 Age-Related Alterations in Neural Plasticity
  • 15 The Aging Immune System: Dysregulation, Compensatory Mechanisms, and Prospects for Intervention
  • 16 Vascular Disease in Hutchinson Gilford Progeria Syndrome and Aging: Common Phenotypes and Potential Mechanisms
  • 17 Cardiac Aging
  • 18 Current Status of Research on Trends in Morbidity, Healthy Life Expectancy, and the Compression of Morbidity
  • 19 On the Compression of Morbidity: From 1980 to 2015 and Beyond