Cargando…
Cytochrome P450 function and pharmacological roles in inflammation and cancer /
Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer, the latest volume in the Advances in Pharmacology series, presents not only the function of cytochrome P450 but also its pharmacological roles in inflammation and cancer. <ul><li>Contains contributions from th...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Waltham, MA :
Academic Press,
2015.
|
| Colección: | Advances in pharmacology (San Diego, Calif.) ;
74. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
MARC
| LEADER | 00000cam a2200000 i 4500 | ||
|---|---|---|---|
| 001 | SCIDIR_ocn915949697 | ||
| 003 | OCoLC | ||
| 005 | 20231120112012.0 | ||
| 006 | m o d | ||
| 007 | cr cnu---unuuu | ||
| 008 | 150806s2015 mau ob 001 0 eng d | ||
| 040 | |a OPELS |b eng |e rda |e pn |c OPELS |d OCLCF |d UAB |d BNG |d OCL |d D6H |d OCLCQ |d UKMGB |d SFB |d OCLCQ |d S4S |d YDXCP |d N$T |d EBLCP |d IDEBK |d FEM |d AU@ |d CUY |d LOA |d ZCU |d MERUC |d ICG |d USU |d K6U |d COCUF |d VT2 |d DKC |d TEF |d OCLCO |d S2H |d OCLCQ |d OCLCO |d COM |d OCLCO |d OCLCQ |d OCLCO | ||
| 066 | |c (S | ||
| 015 | |a GBB584386 |2 bnb | ||
| 016 | 7 | |a 017420190 |2 Uk | |
| 019 | |a 918625276 |a 921239043 |a 928735361 |a 968014558 |a 969016514 | ||
| 020 | |a 9780128031209 |q (electronic bk.) | ||
| 020 | |a 0128031204 |q (electronic bk.) | ||
| 020 | |z 9780128031193 | ||
| 020 | |z 0128031190 | ||
| 035 | |a (OCoLC)915949697 |z (OCoLC)918625276 |z (OCoLC)921239043 |z (OCoLC)928735361 |z (OCoLC)968014558 |z (OCoLC)969016514 | ||
| 050 | 4 | |a QP671.C83 | |
| 060 | 4 | |a WH 190 | |
| 072 | 7 | |a SCI |x 007000 |2 bisacsh | |
| 082 | 0 | 4 | |a 572/.7 |2 23 |
| 245 | 0 | 0 | |a Cytochrome P450 function and pharmacological roles in inflammation and cancer / |c edited by James P. Hardwick. |
| 264 | 1 | |a Waltham, MA : |b Academic Press, |c 2015. | |
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Advances in pharmacology ; |v volume 74 | |
| 588 | 0 | |a Online resource; title from title details screen (ScienceDirect, viewed August 6, 2015). | |
| 504 | |a Includes bibliographical references and index. | ||
| 520 | |a Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer, the latest volume in the Advances in Pharmacology series, presents not only the function of cytochrome P450 but also its pharmacological roles in inflammation and cancer. <ul><li>Contains contributions from the best authors in the field</li><li>Ideal reference for those conducting research in cancer, inflammation, cytochrome P450, metabolism, liver disease, and oxidative stress</li><li>Provides an essential resource for pharmacologists, immunologists, and biochemists</li></ul> | ||
| 505 | 0 | |a Front Cover; Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer; Copyright; Contents; Contributors; Preface; References; Chapter One: Role of Cytochrome P450 Monooxygenase in Carcinogen and Chemotherapeutic Drug Metabolism; 1. Introduction; 2. Historical Aspects of Chemical Carcinogenesis Leading to Discovery of the Cytochrome P450 Monooxygenase; 2.1. Cytochromes P450; 2.2. Butter Yellow Carcinogenesis; 2.3. PAH Carcinogenesis: Protein Adducts and Induction of Metabolism. | |
| 505 | 8 | |a 3. Cytochrome P450-Monooxygenase-Mediated Activation of Procarcinogen and Chemotherapeutic Prodrugs3.1. Aromatic Azo Compounds; 3.2. Polycyclic Aromatic Hydrocarbons; 3.3. Polychlorinated Biphenyls; 3.3.1. Polychlorinated Biphenyls with Low Chlorine Content; 3.3.2. Highly Chlorinated Biphenyls; 3.4. Vinyl Chloride; 3.5. Nitrosamines; 3.6. Furans; 3.7. Chemotherapeutic Prodrugs; 3.7.1. Cyclophosphamide; 3.7.2. Procarbazine and Other Hydrazine Derivatives; 3.7.3. Anthracycline Antibiotics; 4. Factors That Regulate Changes in Gene Expression: Differences Between Rodents and Humans. | |
| 505 | 8 | |a 4.1. Hepatic Nuclear Receptors and Enzyme Induction4.2. Differences Between Rodent and Human Receptors; 4.3. CAR Splice Variants and Ligand Specificity; 4.4. Exogenous Compounds Acting on the PPAR; 4.5. Underlying Regulation by Other Hormones and Transcription Factors; 4.6. Effects of Environmental Agents; 5. Polymorphic Cytochrome P450 Variants Impacting Expression and Cancer Susceptibility; 5.1. Cytochrome P4501A1 and Glutathione S-Transferase M1; 5.2. Cytochrome P4502D6 and Cytochrome P4502E1; 6. Conclusion; Conflict of Interest; Acknowledgment; References. | |
| 505 | 8 | |a Chapter Two: Involvement of Cytochrome P450 in Reactive Oxygen Species Formation and Cancer1. Introduction; 2. Reactive Oxygen Species Formation in Biological Systems; 2.1. Oxygen Reactivity and Formation of Reactive Oxygen Species; 2.2. Types of Reactive Oxygen Species and Their Reactivities; 2.2.1. Superoxide Radical Anion; 2.2.2. Hydrogen Peroxide; 2.2.3. Hydroxyl Radical; 2.2.4. Peroxyl Radical; 2.2.5. Singlet Oxygen; 3. Protective Agents to Combat Reactive Oxygen Species; 3.1. Antioxidants; 3.1.1. Antioxidant Enzymes; 3.1.2. Nonenzymatic Antioxidants; 3.1.2.1. Glutathione. | |
| 650 | 0 | |a Cytochrome P-450. | |
| 650 | 0 | |a Cytochrome P-450 |x Physiological effect. | |
| 650 | 0 | |a Cytochrome P-450 |x Therapeutic use. | |
| 650 | 0 | |a Monooxygenases |x Physiological effect. | |
| 650 | 0 | |a Monooxygenases |x Therapeutic use. | |
| 650 | 0 | |a Inflammation |x Pathophysiology. | |
| 650 | 0 | |a Inflammation |x Treatment. | |
| 650 | 0 | |a Cancer |x Pathophysiology. | |
| 650 | 0 | |a Cancer |x Treatment. | |
| 650 | 2 | |a Cytochrome P-450 Enzyme System |0 (DNLM)D003577 | |
| 650 | 6 | |a Cytochrome P-450. |0 (CaQQLa)201-0082261 | |
| 650 | 6 | |a Cytochrome P-450 |0 (CaQQLa)201-0082261 |x Effets physiologiques. |0 (CaQQLa)201-0374337 | |
| 650 | 6 | |a Cytochrome P-450 |0 (CaQQLa)201-0082261 |x Emploi en th�erapeutique. |0 (CaQQLa)201-0373975 | |
| 650 | 6 | |a Monooxyg�enases |0 (CaQQLa)201-0082262 |x Effets physiologiques. |0 (CaQQLa)201-0374337 | |
| 650 | 6 | |a Monooxyg�enases |0 (CaQQLa)201-0082262 |x Emploi en th�erapeutique. |0 (CaQQLa)201-0373975 | |
| 650 | 6 | |a Inflammation (Pathologie) |0 (CaQQLa)201-0026988 |x Physiopathologie. |0 (CaQQLa)201-0379296 | |
| 650 | 6 | |a Inflammation (Pathologie) |0 (CaQQLa)201-0026988 |x Traitement. |0 (CaQQLa)201-0377521 | |
| 650 | 6 | |a Cancer |x Traitement. |0 (CaQQLa)201-0004693 | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Biochemistry. |2 bisacsh | |
| 650 | 7 | |a Cancer |x Pathophysiology |2 fast |0 (OCoLC)fst00845410 | |
| 650 | 7 | |a Cancer |x Treatment |2 fast |0 (OCoLC)fst00845538 | |
| 650 | 7 | |a Cytochrome P-450 |2 fast |0 (OCoLC)fst00886244 | |
| 650 | 7 | |a Cytochrome P-450 |x Physiological effect |2 fast |0 (OCoLC)fst00886246 | |
| 650 | 7 | |a Inflammation |x Pathophysiology |2 fast |0 (OCoLC)fst00972440 | |
| 700 | 1 | |a Hardwick, James P., |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Cytochrome P450 function and pharmacological roles in inflammation and cancer. |d Waltham, MA : Academic Press, 2015 |z 9780128031193 |w (OCoLC)921176338 |
| 830 | 0 | |a Advances in pharmacology (San Diego, Calif.) ; |v 74. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780128031193 |z Texto completo |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/bookseries/10543589/74 |z Texto completo |
| 880 | 0 | 0 | |6 505-00/(S |t Preface / |r James P. Hardwick -- |t Role of cytochrome P450 monooxygenase in carcinogen and chemotherapeutic drug metabolism / |r B. Wahlang, K. Cameron Falkner, Matt C. Cave, Russell A. Prough -- |t Involvement of cytochrome P450 in reactive oxygen species formation and cancer / |r Eugene G. Hrycay, Stelvio M. Bandiera -- |t Polymorphic variants of cytochrome P450 : relevance to cancer and other diseases / |r Ann K. Daly -- |t Personalized cancer therapy considering cytochrome P450 variability / |r Saskia Preissner, Maurizio Simmaco, Giovanna Gentile, Robert Preissner -- |t Xenobiotic and endobiotic mediated interactions between the cytochrome P450 system and the inflammatory response in the liver / |r Benjamin L. Woolbright, Hartmut Jaeschke -- |t Role of cytochrome P450s in inflammation / |r Peter Christmas -- |t Cytochrome P450-CYP2 family-epoxygenase role in inflammation and cancer / |r Chen Chen, Dao Wen Wang -- |t Cytochrome P450 ω-hydroxylases in inflammation and cancer / |r Amanda L. Johnson, Katheryne Z. Edson, Rheem A. Totah, Allan E. Rettie -- |t Bile acid metabolism and signaling in cholestasis, inflammation, and cancer / |r Tiangang Li, Udayan Apte -- |t Translational implications of the alcohol-metabolizing enzymes, including cytochrome P450-2E1, in alcoholic and nonalcoholic liver disease / |r Byoung-Joon Song, Mohammed Akbar, Inho Jo, James P. Hardwick, Mohamed A. Abdelmegeed -- |t Role of retinoic acid-metabolizing cytochrome P450s, CYP26, in inflammation and cancer / |r Faith Stevison, Jing Jing, Sasmita Tripathy, Nina Isoherranen -- |t Cytochrome P450 vitamin D hydroxylases in inflammation and cancer / |r Charlotte Gr�oschel, Samawansha Tennakoon, Enik�o K�allay. |