Nonclinical assessment of abuse potential for new pharmaceuticals /

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Nonclinical Assessment of Abuse Potential for New Pharmaceuticals offers a complete reference on the current international regulatory guidelines and details best practice methodology for the three standard animal models used to evaluate abuse potential: physical dependence, self-administration and d...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Markgraf, Carrie G. (Editor ), Hudzik, Thomas J. (Editor ), Compton, David R. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam : Academic Press, 2015.
Temas:
Drugs > Overdose.
Opioids > Overdose.
Drug abuse.
Drug addiction.
Prescription Drug Misuse > prevention & control
Substance-Related Disorders > prevention & control
Drug Overdose
Substance-Related Disorders
Drug Evaluation, Preclinical
Models, Animal
M�edicaments > Surdosage.
Opio�ides > Surdosage.
Toxicomanie.
drug addiction.
drug abuse.
POLITICAL SCIENCE > Public Policy > Social Security.
POLITICAL SCIENCE > Public Policy > Social Services & Welfare.
Drug addiction
Drug abuse
Drugs > Overdose
Acceso en línea:Texto completo
Descripción
Sumario:Nonclinical Assessment of Abuse Potential for New Pharmaceuticals offers a complete reference on the current international regulatory guidelines and details best practice methodology for the three standard animal models used to evaluate abuse potential: physical dependence, self-administration and drug discrimination. This book also includes chapters on alternative models and examples of when you should use these alternatives. Case histories are provided at the end of the book to show how the data generated from the animal models play a pivitol role in the submission package for a new drug. B.
Descripción Física:1 online resource
Bibliografía:Includes bibliographical references and index.
ISBN:9780124202160
0124202160

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