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Hybrid retrosynthesis : organic synthesis using Reaxys and SciFinder /
Organic Synthesis and Retrosynthesis: An Applied Approach provides readers with the essential skills they need for both organic synthesis and retrosynthesis, encouraging their practice in real-life problems included within the text. It is designed to supplement existing organic textbooks, not only p...
| Clasificación: | Libro Electrónico |
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| Autores principales: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam, Netherlands :
Elsevier,
[2015]
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Hybrid Retrosynthesis; Copyright Page; Contents; Preface; Common Abbreviations; Summary of Reactions in Chapter 8; 1 Disconnections and Synthesis; 1.A The Disconnection Approach; 1.B Functional Group Exchange Reactions; 2 Making Carbon-Carbon Bonds; 3 Computer-Assisted Syntheses; 4 A Hybrid Retrosynthesis Approach; 5 Creative Strategies to Searching for Reagents; 6 Stereochemistry; 7 Molecules of Greater Complexity; 7.A Convergent Syntheses; 7.B Perovskone; 7.C Amphotericin B; 7.D Carbovir; 8 Common Fundamental Reactions in Organic Chemistry.
- 8.A Functional Group Exchange ReactionsAcetals and Ketals; 1 From Aldehydes or Ketones; Acid Chlorides; 2 From Carboxylic Acids; Alcohols; 3 From Acid Derivatives (acid chlorides, anhydrides, esters); 4 From Alkenes; 5 From Ethers; 6 From Ketones or Aldehydes; Alcohol-Alcohol; Alcohols-Functionalized; 7 From Epoxides or Alkenes; Aldehydes or Ketones; 8 From Acetals; 9 From Alcohols; 10 From Alkenes; 11 From Alkynes; 12 From Diols; 13 From Nitriles; Alkanes; 14 From Alkenes; 15 From Alkyl Halides; 16 From Ketones or Aldehydes; Alkenes; 17 From Alkynes.
- 18 From Halides, Sulfonate Esters, or Ammonium SaltsAlkyl Halides; Alkynes; 19 From Alkenyl Halides; Amides; 20 From Acid Derivatives; 21 From Nitriles; Amines; 22 From Azides, Imides, and Halides; 23 From Nitriles; 24 From Nitro Compounds; Anhydrides; 25 From Carboxylic Acids and Acid Derivatives; Aryl Halides; Carboxylic Acids; 26 From Acid Derivatives (acid chlorides, anhydrides, esters, amides); 27 From Alcohols; 28 From 1,3-Dicarboxylic Acids; 29 From Nitriles; Dienes; 30 From Aromatics; Dihalides; Diols; 31 From Alkenes; 32 From Epoxides; Enamines; 33 From Ketones or Aldehydes; Epoxides.
- 34 From Alkenes35 From Halohydrins; Esters; 36 From Carboxylic Acids and Acids Derivatives; 37 From Ketones; Ethers; 38 From Alcohols; Halides (Alkyl); 39 From Alcohols; 40 From Alkanes and Aryls; 41 From Alkenes; 42 From Alkyl Halides; Halides (Alkenyl); 43 From Alkynes; Imines; 44 From Ketones or Aldehydes; Ketals; Ketones or Aldehydes. See Aldehydes; 45 From Alkynes; 46 From Diols; 47 From Ketone-Acids; Nitriles; 48 From Amides; Nitro Compounds; 49 From Aromatics; Organometallics; 50 From Alkyl Halides; Phenols; 51 From Aryl Halides; Phosphonium Salts; 52 From Alkyl Halides; Sulfonic Acids.
- 53 From Aromatics8.B Carbon-Carbon Bond Forming Reactions; Alcohols; 54 From Acid Derivatives and Organometallics; 55 From Epoxides; 56 From Ketones or Aldehydes and Organometallics; Alcohols-Esters; 57 From Esters; Alcohol-Ketones; Aldehydes and Ketones; 58 From Aldehydes or Ketones and Alkyl Halides; 59 From Organometallics and Dimethylformamide (DMF); Aldehyde-Alkenes; 60 From Allylic Vinyl Ethers; Alkanes; 61 From Alkenes; 62 From Alkyl Halides and Organometallics; Alkenes; 63 From Alkenes and Aryl Halides (Heck reaction); 64 From Alkenes and Dienes; 65 From Dienes.