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Recent advances in medicinal chemistry. Volume 1 /
Originally published by Bentham and now distributed by Elsevier, Recent Advances in Medicinal Chemistry, Volume 1 covers leading-edge research and recent developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets,...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam, Netherlands :
Elsevier Ltd.,
[2014]
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 020 | |a 9780128039618 |q (electronic bk.) | ||
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| 245 | 0 | 0 | |a Recent advances in medicinal chemistry. |n Volume 1 / |c edited by Atta-ur-Rahman, Muhammad Iqbal Choudhary, George Perry. |
| 264 | 1 | |a Amsterdam, Netherlands : |b Elsevier Ltd., |c [2014] | |
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 588 | 0 | |a Online resource; title from PDF title page (EBSCO, viewed June 24, 2015). | |
| 504 | |a Includes bibliographical references and index. | ||
| 520 | |a Originally published by Bentham and now distributed by Elsevier, Recent Advances in Medicinal Chemistry, Volume 1 covers leading-edge research and recent developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies. The fourteen updated reviews include unique experimental data and references, and each article highlights an important topic in current medicinal chemistry research. Topics covered include: aureolic acid group of anti-cancer antibiotics and non-steroidal anti-inflammatory drugs; aromatase inhibitors in adjuvant endocrine treatment of early-stage breast cancer in postmenopausal women; Rho GTPases and statins in targeting and developing therapies for tumors; and more. | ||
| 505 | 0 | |a Front Cover; Recent Advances in Medicinal Chemistry, Volume 1; Copyright; Contents ; Foreword ; Preface ; List of Contributors ; Chapter 1: New Functions of Old Drugs: Aureolic Acid Group of Anti-Cancer Antibiotics and Non-Steroidal Anti-Inflammatory Drugs ; Abstract ; 1. Introduction ; 2. Principal Functions of Nsaids and Aureolic Acid Anticancer Antibiotics and Their Mechanism of Action ; 3. Other Functions of These Drugs and Mechanism of Actions ; 4. Chemical Dissection of the Drugs to Understand Alternate Functions ; 5. Conclusion ; Acknowledgements ; Conflict of Interest ; Disclosure | |
| 505 | 8 | |a Chapter 3: Characterization of Inorganic Nanomaterials as Therapeutic Vehicles Abstract ; Introduction ; Concluding Remarks ; Acknowledgements ; Conflict of Interest ; Disclosure ; References ; Chapter 4: Aromatase Inhibitors: A New Reality for the Adjuvant Endocrine Treatment of Early-Stage Breast Cancer in Postmenopausal Women ; Abstract ; Introduction ; Conclusions ; Acknowledgements ; Conflict of Interest ; Disclosure ; References ; Chapter 5: Bacterial FabH: Towards the Discovery of New Broad-Spectrum Antibiotics ; Abstract ; Introduction ; Bacterial Type II Fas the Biological Process | |
| 505 | 8 | |a Three Dimensional Structure of FabH Substrate Binding and Specificity ; Catalytic Mechanism and Substrate Binding ; Molecular Modeling Studies of FabH ; Concluding Remarks ; Acknowledgements ; Conflict of Interest ; Disclosure ; References ; Chapter 6: Tannins and Their Influence on Health ; Abstract ; 1. Introduction ; 2. Classification of Tannins ; 3. Absorption and Metabolism of Tannins ; 4. Biological Activity ; 5. Human Intervention Studies ; 6. Adverse and Undesirable Effects ; 7. Conclusions ; Acknowledgements ; Conflict of Interest ; Disclosure ; Abbreviations ; References | |
| 505 | 8 | |a Chapter 7: Rho-GTPases and Statins: A Potential Target and a Potential Therapeutic Tool Against Tumors? Abstract ; Introduction ; Role of RhoA in Normal and Tumor Cells ; Statins Inhibit RhoA Activity ; Statins and Tumor Growth/apoptosis ; Statins and Angiogenesis ; Statins and Metastasis ; Statins, Chemotherapy Efficacy and Multidrug Resistance ; Statins and Chemoprevention of Tumors ; Statins in Cancer Treatment ; Acknowledgements ; Conflict of Interest ; Disclosure ; References ; Chapter 8: Carotenoids that are Involved in Prostate Cancer Risk ; Abstract ; Introduction | |
| 650 | 0 | |a Pharmaceutical chemistry. | |
| 650 | 2 | |a Chemistry, Pharmaceutical |0 (DNLM)D002626 | |
| 650 | 6 | |a Chimie pharmaceutique. |0 (CaQQLa)201-0028674 | |
| 650 | 7 | |a MEDICAL |x Pharmacology. |2 bisacsh | |
| 650 | 7 | |a Pharmaceutical chemistry |2 fast |0 (OCoLC)fst01060115 | |
| 700 | 1 | |a Rahman, Atta-ur-, |d 1942- |e editor. | |
| 700 | 1 | |a Choudhary, Muhammad Iqbal, |e editor. | |
| 700 | 1 | |a Perry, George, |e editor. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780128039618 |z Texto completo |