Cargando…
Systems biology in toxicology and environmental health /
Systems Biology in Toxicology and Environmental Health uses a systems biological perspective to detail the most recent findings that link environmental exposures to human disease, providing an overview of molecular pathways that are essential for cellular survival after exposure to environmental tox...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam :
Elsevier,
2015.
|
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Systems Biology in TOXICOLOGY AND ENVIRONMENTAL HEALTH; Copyright; CONTENTS; CONTRIBUTORS; PREFACE; Chapter 1
- Systems Biology in Toxicology and Environmental Health; SYSTEMS BIOLOGY DEFINED; TECHNOLOGIES UTILIZED IN SYSTEMS BIOLOGY; APPLICATIONS OF SYSTEMS BIOLOGY IN ENVIRONMENTAL HEALTH; APPLICATIONS OF SYSTEMS BIOLOGY IN TOXICOLOGY; APPLICATIONS OF SYSTEMS BIOLOGY IN THE CLINIC; SUMMARY; REFERENCES; Chapter 2
- The Cell: The Fundamental Unit in Systems Biology; INTRODUCTION; THE CELL: STRUCTURE AND ORGANELLES; CELLULAR SIGNALING: PLASMA MEMBRANE AND SIGNAL TRANSDUCTION.
- CELLULAR HOMEOSTASIS (I): ENERGY METABOLISMDECODING THE GENOME (I): TRANSCRIPTION; DECODING THE GENOME (II): TRANSLATION; CELLULAR HOMEOSTASIS (II): CELL DIFFERENTIATION, DEATH; REFERENCES; Chapter 3
- Systems Biology and the Epigenome; INTRODUCTION; DNA METHYLATION; MOLECULAR BASIS OF DNA METHYLATION; POSTTRANSLATIONAL HISTONE MODIFICATIONS; CHROMATIN; REFERENCES; Chapter 4
- Omics Technologies Used in Systems Biology; INTRODUCTION; GENOMICS; GENERATION OF MICROARRAY DATA; GENOMIC DATA GENERATION USING WHOLE TRANSCRIPTOME SHOTGUN SEQUENCING (RNA-SEQ); PROTEOMICS; METABOLOMICS; SUMMARY.
- IMMUNODEFICIENCY DISEASESAUTOIMMUNE DISEASES; IMMUNE FUNCTION AND TYPE 1 DIABETES; ENVIRONMENTAL EXPOSURES AND THEIR IMPACT ON IMMUNE-RELATED SIGNALING PATHWAYS; ARSENIC AND THE IMMUNE SYSTEM; CADMIUM EFFECTS ON THE IMMUNE SYSTEM; AIR POLLUTION AND IMMUNE FUNCTION; MERCURY; CONCLUSIONS; REFERENCES; Chapter 8
- The Role of Apoptosis-Associated Pathways as Responders to Contaminants and in Disease Progression; INTRODUCTION TO APOPTOSIS; CANONICAL PATHWAYS THAT REGULATE APOPTOSIS INITIATION; APOPTOSIS SIGNALING PATHWAYS AND DISEASE; APOPTOSIS PATHWAYS THAT ARE ALTERED BY ENVIRONMENTAL COMPOUNDS.