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Streptococcus pneumoniae : molecular mechanisms of host-pathogen interactions /

Streptococcus Pneumoniae: Molecular Mechanisms of Host-Pathogen Interactions provides a comprehensive overview of our existing knowledge on Streptococcus pneumoniae antibiotic resistance, dissemination, and pathogenesis, including immunology. It presents a state-of-the-art overview of the implicatio...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Brown, Jeremy, 1964- (Editor ), Hammerschmidt, Sven (Editor ), Orihuela, Carlos (Carlos J.) (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam : Academic Press, [2015]
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; Streptococcus pneumoniae; Copyright Page; Contents; List of Contributors; Preface; A. Streptococcus pneumoniae Epidemiology and Vaccines; 1 Molecular Epidemiology of Streptococcus pneumoniae; Etiological Diagnosis of Pneumococcal Infections; Some Basic Concepts in Molecular Epidemiology; Serotyping and Molecular Typing of S. pneumoniae; Serotyping; Pulsed-Field Gel Electrophoresis; Multilocus Sequence Typing; Other Typing Methods; Whole Genome Sequencing; Clones of S. pneumoniae; References; 2 Antibiotic Resistance of Pneumococci; Introduction; Risk Factors for Resistance.
  • Introduction of PCV Has Led to Direct and Indirect Protection Against Antimicrobial ResistanceConcluding Remarks; References; 3 Pneumococcal Vaccination and Consequences; Effect of the Vaccine on Pneumococcal Carriage; Effect of the Vaccine on the Disease; Impact of Conjugate Vaccines on Mucosal Infection; Effect of Conjugate Vaccines on IPD; Impact on Clinical Manifestations; Effect of PCV in Bacteremia and Meningitis; Effect of PCV in Pneumonia; Impact on Antimicrobial Resistance; Pneumococcal Conjugate Vaccination for Older Adults; Conclusion; References.
  • 4 Vaccine Potential of Pneumococcal ProteinsIntroduction; Next-Generation Pneumococcal Vaccine Candidates and Strategies; Pneumolysin; Choline-Binding Proteins; Pneumococcal Surface Protein A; Pneumococcal Surface Protein C; Autolysin (LytA); Pneumococcal Choline-Binding Protein; Lipoproteins; Pneumococcal Surface Antigen A; PiuA and PiaA; Other Lipoprotein Vaccine Candidates; Pht Proteins; Sortase-Dependent Surface Proteins and Other Secreted Proteins; Recently Characterized Protein Vaccine Candidates; PcsB and StkP; AliA and GlpO; Whole Cell Vaccines; Conclusions and Future Perspectives.