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Circadian rhythms and biological clocks. Volume 552, Part B /
Two new volumes of Methods in Enzymology continue the legacy of this premier serial with quality chapters authored by leaders in the field. Circadian Rhythms and Biological Clocks Part A and Part B is an exceptional resource for anybody interested in the general area of circadian rhythms. As key ele...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam, Netherlands :
Elsevier Academic Press,
2015.
|
| Colección: | Methods in enzymology ;
v. 552. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo Texto completo |
MARC
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| 245 | 0 | 0 | |a Circadian rhythms and biological clocks. |n Volume 552, |p Part B / |c edited by Amita Sehgal. |
| 264 | 1 | |a Amsterdam, Netherlands : |b Elsevier Academic Press, |c 2015. | |
| 264 | 4 | |c �2015 | |
| 300 | |a 1 online resource (xviii, 395 pages) : |b illustrations (chiefly color) | ||
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| 490 | 1 | |a Methods in enzymology, |x 0076-6879 ; |v volume 552 | |
| 504 | |a Includes bibliographical references and indexes. | ||
| 588 | 0 | |a PDF (ScienceDirect, viewed on February 27, 2015). | |
| 520 | |a Two new volumes of Methods in Enzymology continue the legacy of this premier serial with quality chapters authored by leaders in the field. Circadian Rhythms and Biological Clocks Part A and Part B is an exceptional resource for anybody interested in the general area of circadian rhythms. As key elements of timekeeping are conserved in organisms across the phylogenetic tree, and our understanding of circadian biology has benefited tremendously from work done in many species, the volume provides a wide range of assays for different biological systems. Protocols are provided to assess clock function, entrainment of the clock to stimuli such as light and food, and output rhythms of behavior and physiology. This volume also delves into the impact of circadian disruption on human health. Contributions are from leaders in the field who have made major discoveries using the methods presented here. | ||
| 505 | 0 | |a pt. I Dissecting the Central Clock Circuit -- 1. Measuring Synchrony in the Mammalian Central Circadian Circuit / Cristina Mazuski -- 1. Introduction -- 2. Monitoring SCN Rhythms with Cellular Resolution -- 3. Isolating Data from Single Cells -- 4. Defining a Rhythm -- 5. Period Synchrony: Methods to Extract and Compare Periods Between Cells -- 6. Phase Synchrony: Methods to Extract and Compare Phase Relationships Between Cells -- 7. Perturbations Reveal Synchronization Mechanisms -- 8. Methods Awaiting Application in Circadian Biology -- 9. Step-by-Step Instructions for Measuring Synchrony in SCN Slice -- Acknowledgments -- References -- 2. Patch-Clamp Electrophysiology in Drosophila Circadian Pacemaker Neurons / Ravi Allada -- 1. The Drosophila Circadian Network -- 2. Circadian Control of Neuronal Activity -- 3. Methods for Patch-Clamp Electrophysiology -- 4. Conclusion -- Acknowledgments -- References -- 3. Glial Cell Regulation of Rhythmic Behavior / Yanmei Huang -- 1. Introduction -- 2. Studies of Glial Cell Function in Circadian Behavior and Sleep -- 3. Potential Circadian Glia -- Neuron Signaling Molecules -- 4. Molecular Genetic Strategies for Studying the Glial Regulation of Drosophila Rhythms 59 -- Appendix A. Protocol for TRAP Profiling of Fly Glial Cells -- References -- 4. Neurophysiological Analysis of the Suprachiasmatic Nucleus: A Challenge at Multiple Levels / Stephan Michel -- 1. Introduction -- 2. Part I: Clock Mechanisms at the Cellular Level -- 3. Part II: The SCN as a Multi-Oscillator -- 4. Part III: In Vivo Electrophysiology Recordings from the SCN in Anesthetized and Freely Moving Animals -- 5. Conclusions -- Acknowledgments -- References -- pt. II Entrainment of Central and Peripheral Clocks -- 5. Photic Entrainment in Drosophila Assessed by Locomotor Activity Recordings / Charlotte Helfrich-Forster -- 1. Introduction -- 2. Different Light Regimes Used to Entrain Locomotor Activity of Fruit Flies -- 3. Methods to Measure Locomotor Activity -- 4. Data Analysis and System Comparison -- References -- 6. Photic Regulation of Clock Systems / Stuart N. Peirson -- 1. Introduction -- 2. The Suprachiasmatic Nuclei -- 3. The Molecular Circadian Clock -- 4. Peripheral Clocks -- 5. Photoentrainment and Melanopsin -- 6. Entrainment of the Molecular Clock -- 7. Molecular Photoentrainment -- 8. Studying the Effects of Light on the Circadian Clock -- 9. Conclusions -- Acknowledgments -- References -- 7. Response of Peripheral Rhythms to the Timing of Food Intake / Satchidananda Panda -- 1. Introduction -- 2. Animal Strain and Age -- 3. Animal Room and Equipment -- 4. Facilities to Accommodate Feeding Schedule -- 5. Diet -- 6. Monitoring Eating Pattern -- 7. Physiological Readout of Eating Pattern -- 8. Feeding Paradigms -- 9. Mouse Tissue Collection -- 10. Transcript, Protein, and Metabolome Expression Analysis -- 11. Conclusion -- References -- pt. III Clocks and Metabolic Physiology -- 8. Circadian Regulation of Cellular Physiology / J. Bass -- 1. Introduction -- 2. Materials -- 3. Methods -- 4. Notes -- Acknowledgments -- References -- 9. Analysis of the Redox Oscillations in the Circadian Clockwork / Akhilesh B. Reddy -- 1. Introduction: Circadian and Redox Coupling in the Cell -- 2. The Biochemical Properties of the Peroxiredoxin System -- 3. Analysis of PRX Redox Oscillations -- Acknowledgments -- References -- 10. Clocks and Cardiovascular Function / Garret A. FitzGerald -- 1. Introduction -- 2. Circadian Analysis of Physiological Parameters with Radiotelemetry -- 3. Primary Cell Culture of Macrophages -- 4. Circadian Variation in Thrombogenesis -- 5. Atherosclerosis and Vascular Integrity in Models of Clock Disruption -- 6. Clocks and Myocardial Dysfunction -- 7. Conclusion -- References -- pt. IV Circadian Rhythms in Humans -- 11. Measuring Circadian Clock Function in Human Cells / Steven A. Brown -- 1. Introduction -- 2. Studies of Circadian Clock Properties Using Reporters -- 3. Ex Vivo and In Vitro Studies of Human Circadian Clocks -- 4. Similar Technologies to Study Other Major Signaling Pathways -- 5. Cell-Based Approaches to Study Gene Expression Variation and Human Interindividual Differences in Drug Responses -- 6. Promise of In Vitro Gene Expression Profiling -- 7. Specific Protocols -- 8. Perspectives -- Acknowledgments -- References -- 12. Human Activity and Rest In Situ / Eva C. Winnebeck -- 1. Introduction -- 2. Probing Activity and Sleep by Questionnaires -- 3. Measuring Activity and Sleep by Actimetry -- 4. Concluding Remarks -- References -- 13. Phenotyping of Neurobehavioral Vulnerability to Circadian Phase During Sleep Loss / David F. Dinges -- 1. Prevalence and Consequences of Sleep Loss -- 2. Sleep-Wake and Circadian Regulation: Two-Process Model -- 3. Subjective and Objective Measures for Circadian Variation in Performance -- 4. Circadian Variation Assessment in Neurobehavioral Functions -- 5. Sleep Deprivation and Performance -- 6. Cumulative Effects on Performance from Chronic Sleep Restriction -- 7. Phenotypic Individual Differences in Response to Sleep Deprivation -- 8. The PVT: Example of a Behavioral Assay for Phenotyping Responses to Sleep Loss -- 9. Conclusions -- Acknowledgments -- References -- 14. Genetics of Human Sleep Behavioral Phenotypes / Ying-Hui Fu -- 1. Introduction -- 2. Clinical Phenotyping -- 3. Identification of Associated Genetic Variants -- 4. Modeling Human Sleep Phenotypes in Rodents -- 5. Concluding Remarks -- Acknowledgments -- References -- 15. Sleep and Circadian Rhythm Disruption and Recognition Memory in Schizophrenia / Stuart N. Peirson -- 1. Introduction -- 2. Sleep and Circadian Rhythm Disruption in Schizophrenia -- 3. Recognition Memory Deficits in Schizophrenia -- 4. Recognition Memory Deficits After the Direct Manipulation of Sleep and Circadian Rhythms -- 5. Dual-Process Theory of Recognition -- 6. Which is Impaired, Recollection or Familiarity? -- 7. Is There an Association Between Sleep and Circadian Function and Recognition Memory in Schizophrenia? -- 8. Summary of the Chapter and Some Unresolved Issues -- Acknowledgments -- References. | |
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| 776 | 0 | 8 | |i Print version: |t Methods in enzymology. Part B, Circadian rhythms and biological clocks. |b First edition. |d London, England : Academic Press, �2015 |h xviii, 395 pages |k Methods in enzymology ; Volume 552 |x 0076-6879 |z 9780128033807 |
| 830 | 0 | |a Methods in enzymology ; |v v. 552. |x 0076-6879 | |
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