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Autophagy. cancer, other pathologies, inflammation, immunity, infection, and aging / Volume 7, Role of autophagy in therapeutic applications :
Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and up-to-date, this book offers a valuable guide to these cellular processes whilst inciting res...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego, CA :
Academic Press,
2015.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Autophagy; Copyright Page; Dedication; Mitophagy and Biogenesis; Autophagy and Cancer; Some Thoughts on Autophagy and Immunity; Autophagy: Friend or Foe?; Contents; Foreword by Roberta A. Gottlieb; Foreword by Eeva-Liisa Eskelinen; Preface; Contributors; Abbreviations and Glossary; Autophagy: Volume 1
- Contributions; Autophagy: Volume 2
- Contributions; Autophagy: Volume 3
- Contributions; Autophagy: Volume 4
- Contributions; Autophagy: Volume 5
- Contributions; Autophagy: Volume 6
- Contributions.
- 1 Introduction to Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 7Introduction; Specific Functions of Autophagy (A Summary); Autophagy in Normal Mammalian Cells; Endoplasmic Reticulum Stress and Autophagy; Major Types of Autophagies; Macroautophagy (Autophagy); Microautophagy; Chaperone-Mediated Autophagy; Autophagosome Formation; Autophagic Lysosome Reformation; Autophagic Proteins; Abnormal Proteins; Protein Degradation Systems; Beclin 1; Non-Autophagic Functions of Autophagy-Related Proteins; Microtubule-Associated Protein Light Chain 3.
- Monitoring AutophagyReactive Oxygen Species (ROS); Mammalian Target of Rapamycin (mTOR); Role of Autophagy in Tumorigenesis and Cancer; Role of Autophagy in Immunity; Autophagy and Senescence; Role of Autophagy in Viral Defense and Replication; Role of Autophagy in Intracellular Bacterial Infection; Role of Autophagy in Heart Disease; Role of Autophagy in Neurodegenerative Diseases; Cross-Talk between Autophagy and Apoptosis; Autophagy and Ubiquitination; Aggresome: Ubiquitin Proteasome and Autophagy Systems; Autophagy and Necroptosis; Mitochondrial Fusion and Fission; Selective Autophagies.
- AllophagyAxonophagy (Neuronal Autophagy); Crinophagy; Exophagy; Glycophagy; Lipophagy; Role of Lipophagy in Alcohol-Induced Liver Disease; Mitophagy; Nucleophagy; Pexophagy; Reticulophagy; Ribophagy; Xenophagy; Zymophagy; References; I. Autophagosome Biogenesis and Regulation; 2 Role of Endoplasmic Reticulum in the Formation of Phagophores/Autophagosomes: Three-Dimensional Morphology; Introduction; The Autophagic Pathway; Why is the Phagophore so Elusive?; Origin of the Phagophore Membrane; Capturing Phagophore Biogenesis Using Electron Microscopy and Electron Tomography.
- Electron Tomography Reveals Connections between the Phagophore and the ERA Note on Sample Preparation for Electron Tomography; Methodology for Chemical and Cryofixation of Cells; Electron Tomography; Concluding Remarks; Acknowledgments; References; 3 The Nucleus-Vacuole Junction in Saccharomyces cerevisiae; Introduction; Structure of the Nucleus-Vacuole Junction; Functions of the Nucleus-Vacuole Junction; Piecemeal Microautophagy of the Nucleus; Role of Nucleus-Vacuole Junctions in Lipid Metabolism; Similar Functions in Mammals; Conclusion and Perspectives; References.