Chemical modulators of protein misfolding and neurodegenerative disease /

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This book is a neurochemistry-based companion for Protein Misfolding and Neurodegenerative Diseases: Molecular Targets, an Elsevier title by the same author publishing in December 2014. While the first book focuses on biology and molecular targets, this companion book describes how these targets are...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Seneci, Pierfausto, 1960- (Autor)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam : Boston : Elsevier/AP, Academic Press is an imprint of Elsevier, [2015]
Temas:
Protein folding.
Molecular neurobiology.
Nervous system > Degeneration.
Nervous system > Diseases.
Tauopathies
Molecular Targeted Therapy > methods
Protein Folding
Nervous System Diseases
Prot�eines > Repliement.
Neurobiologie mol�eculaire.
Syst�eme nerveux > Maladies.
SCIENCE > Life Sciences > Biochemistry.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Chemical modulators of protein misfolding, neurodegeneration and tau
  • Targeting the protein quality-control (PQC) machinery
  • Targeting proteasomal degradation of soluble, misfolded proteins
  • Targeting unselective autophagy of cellular aggregates
  • Targeting selective autophagy of insoluble protein aggregates
  • Targeting assembly and disassembly of protein aggregates.

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