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Handbook of arsenic toxicology /

Throughout history, arsenic has been used as an effective and lethal poison. Today, arsenic continues to present a real threat to human health all over the world, as it contaminates groundwater and food supplies. Handbook of Arsenic Toxicology presents the latest findings on arsenic, its chemistry,...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Flora, S. J. S.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Academic Press, an imprint of Elsevier Science, 2015.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Machine generated contents note: 1.1. Introduction / Swaran J.S. Flora
  • 1.2. Chemistry of Arsenic / Swaran J.S. Flora
  • 1.3. Arsenic Minerals and Compounds / Swaran J.S. Flora
  • 1.4.Organoarsenicals / Swaran J.S. Flora
  • 1.5. Arsenic Mobilization in the Environment / Swaran J.S. Flora
  • 1.6. Sources of Arsenic in the Biosphere / Swaran J.S. Flora
  • 1.7. Arsenic in Hydrothermal and Geothermal Fluids / Swaran J.S. Flora
  • 1.8. Arsenic Release from Mining and Mineral Processing / Swaran J.S. Flora
  • 1.9. Global Occurrence of Arsenic in Ground Water / Swaran J.S. Flora
  • 1.10. Methods of Arsenic Removal from Water / Swaran J.S. Flora
  • 1.11. Conclusions / Swaran J.S. Flora
  • References / Swaran J.S. Flora
  • 2.1. Introduction / Manzurul Haque Khan / 5k Akhtar Ahmad
  • 2.2. Arsenic Contamination in Bangladesh Ground Water / Manzurul Haque Khan / 5k Akhtar Ahmad
  • 2.3. Extent of Arsenic Contamination in Bangladesh / Manzurul Haque Khan / 5k Akhtar Ahmad.
  • Note continued: 2.4. Arsenic in Different Environmental Media of Bangladesh / Manzurul Haque Khan / 5k Akhtar Ahmad
  • 2.5. Health Effects of Arsenic Toxicity in Bangladesh / Manzurul Haque Khan / 5k Akhtar Ahmad
  • 2.6. Epidemiology of Arsenicosis in Bangladesh / Manzurul Haque Khan / 5k Akhtar Ahmad
  • 2.7. Management of Arsenicosis Patients in Bangladesh / Manzurul Haque Khan / 5k Akhtar Ahmad
  • 2.8. Socio-Cultural Aspects of Arsenicosis in Bangladesh / Manzurul Haque Khan / 5k Akhtar Ahmad
  • 2.9. Conclusions / Manzurul Haque Khan / 5k Akhtar Ahmad
  • References / Manzurul Haque Khan / 5k Akhtar Ahmad
  • 3.1. Introduction / Shafi M. Tareq
  • 3.2. Materials and Methods / Shafi M. Tareq
  • 3.3. Results and Discussion / Shafi M. Tareq
  • 3.4. Conclusions / Shafi M. Tareq
  • References / Shafi M. Tareq
  • 4.1. Introduction / Santhini Ramasamy / Janice S. Lee
  • 4.2. Arsenic Chemistry / Janice S. Lee / Santhini Ramasamy.
  • Note continued: 4.3. Arsenic Occurrence and Exposure / Janice S. Lee / Santhini Ramasamy
  • 4.4. Hazard Identification / Janice S. Lee / Santhini Ramasamy
  • 4.5. Arsenic Metabolism, Mode of Action, and Physiologically Based Pharmacokinetic Modeling / Janice S. Lee / Santhini Ramasamy
  • 4.6. Potential Sources of Susceptibility / Janice S. Lee / Santhini Ramasamy
  • 4.7. Dose-Response Approaches / Janice S. Lee / Santhini Ramasamy
  • 4.8. Risk Characterization / Janice S. Lee / Santhini Ramasamy
  • Disclaimer / Janice S. Lee / Santhini Ramasamy
  • References / Janice S. Lee / Santhini Ramasamy
  • 5.1. Introduction / Lucy Mar Camacho / Sundaravadivelnathan Ponnusamy / Shuguang Deng / Thomas A. Davis / Isaac Campos
  • 5.2. Materials and Methods / Lucy Mar Camacho / Sundaravadivelnathan Ponnusamy / Shuguang Deng / Thomas A. Davis / Isaac Campos
  • 5.3. Results and Discussion / Lucy Mar Camacho / Sundaravadivelnathan Ponnusamy / Shuguang Deng / Thomas A. Davis / Isaac Campos.
  • Note continued: 5.4. Conclusions / Lucy Mar Camacho / Sundaravadivelnathan Ponnusamy / Shuguang Deng / Thomas A. Davis / Isaac Campos
  • Acknowledgments / Lucy Mar Camacho / Sundaravadivelnathan Ponnusamy / Shuguang Deng / Thomas A. Davis / Isaac Campos
  • References / Lucy Mar Camacho / Sundaravadivelnathan Ponnusamy / Shuguang Deng / Thomas A. Davis / Isaac Campos
  • 6.1. Introduction / D.N. Guha Mazumder
  • 6.2. Dermatological Manifestations / D.N. Guha Mazumder
  • 6.3. Epidemiological Study of Dermatological Manifestations / D.N. Guha Mazumder
  • 6.4. Pregnancy Outcome / D.N. Guha Mazumder
  • 6.5. Arsenicosis and Cancer / D.N. Guha Mazumder
  • 6.6. Diagnosis / D.N. Guha Mazumder
  • 6.7. Treatment / D.N. Guha Mazumder
  • References / D.N. Guha Mazumder
  • 7.1. Introduction / Badal Kumar Mandal
  • 7.2. Conclusions / Badal Kumar Mandal
  • References / Badal Kumar Mandal
  • 8.1. Introduction / Parames C. Sil / Jyotirmoy Ghosh.
  • Note continued: 8.2. Biological Consequences of Chronic Arsenic Exposure in Humans / Parames C. Sil / Jyotirmoy Ghosh
  • 8.3. Arsenic Metabolism / Jyotirmoy Ghosh / Parames C. Sil
  • 8.4. Pathophysiology of Arsenic Toxicity / Parames C. Sil / Jyotirmoy Ghosh
  • 8.5. Mechanism for the Toxic Effects of Arsenic / Jyotirmoy Ghosh / Parames C. Sil
  • 8.6. Preventing Arsenic-Induced Toxic Effects by Antioxidants / Jyotirmoy Ghosh / Parames C. Sil
  • 8.7. Conclusions and Future Directions / Jyotirmoy Ghosh / Parames C. Sil
  • References / Jyotirmoy Ghosh / Parames C. Sil
  • 9.1. Arsenic, a Potent Mutagen and Carcinogen / Smarajit Maiti
  • 9.2. Epidemiological Perspectives of Arsenic-Induced Human Cancers / Smarajit Maiti
  • 9.3. Arsenic-Associated Metabolism and Carcinogenesis in Animal Models / Smarajit Maiti
  • 9.4. Human Arsenic Carcinogenesis / Smarajit Maiti
  • 9.5. Conclusions and Future Directions / Smarajit Maiti
  • Acknowledgments / Smarajit Maiti.
  • Note continued: References / Smarajit Maiti
  • 10.1. General Aspects / Jos�e Mois�es Laparra Llopis / Marta Calatayud
  • 10.2. Arsenic in Foods: Household Processing and Toxicological Risk / Jos�e Mois�es Laparra Llopis / Marta Calatayud
  • 10.3. Role of the Gut in Arsenic Toxicity: Bioavailability and Intestinal Health / Marta Calatayud / Jos�e Mois�es Laparra Llopis
  • 10.4. Arsenic-Induced Metabolic/Immune Toxicity / Jos�e Mois�es Laparra Llopis / Marta Calatayud
  • 10.5. Conclusions and Future Perspectives / Marta Calatayud / Jos�e Mois�es Laparra Llopis
  • References / Jos�e Mois�es Laparra Llopis / Marta Calatayud
  • 11.1. Introduction / Mohammad Athar / Ritesh Kumar Srivastava / Katherine Marchiony Hunt
  • 11.2. Epidemiology / Ritesh Kumar Srivastava / Mohammad Athar / Katherine Marchiony Hunt
  • 11.3. Clinical Manifestations / Mohammad Athar / Katherine Marchiony Hunt / Ritesh Kumar Srivastava.
  • Note continued: 11.4. Histopathology / Katherine Marchiony Hunt / Ritesh Kumar Srivastava / Mohammad Athar
  • 11.5. Molecular Pathogenesis / Katherine Marchiony Hunt / Ritesh Kumar Srivastava / Mohammad Athar
  • 11.6. Treatment / Mohammad Athar / Katherine Marchiony Hunt / Ritesh Kumar Srivastava
  • References / Mohammad Athar / Ritesh Kumar Srivastava / Katherine Marchiony Hunt
  • 12.1. Introduction / Amal Santra
  • 12.2. Source of Exposure / Amal Santra
  • 12.3. Biotransformation and Elimination of Arsenic / Amal Santra
  • 12.4. History of Arsenic-Related Liver Diseases / Amal Santra
  • 12.5. Hepatoportal Sclerosis / Amal Santra
  • 12.6. Arsenic-Related Hepatic Fibrosis and Cirrhosis / Amal Santra
  • 12.7. Epidemiological Study to Assess Arsenic-Related Liver Dysfunction / Amal Santra
  • 12.8. Animal Studies for Understanding the Pathogenesis / Amal Santra
  • 12.9. Arsenic and Liver Cancer / Amal Santra
  • References / Amal Santra
  • 13.1. Introduction / Kathryn Ramsey.
  • Note continued: 13.2. Chronic Arsenic Exposure and Respiratory Health / Kathryn Ramsey
  • 13.3. Early Life Arsenic Exposure and Lung Health / Kathryn Ramsey
  • 13.4. Mechanistic Data on Arsenic Exposure and the Lung / Kathryn Ramsey
  • 13.5. Conclusions / Kathryn Ramsey
  • References / Kathryn Ramsey
  • 14.1. Introduction / Bruce A. Fowler
  • 14.2. Clinical Manifestations of Arsenical Toxicity in Humans / Bruce A. Fowler
  • 14.3. Nephrotoxic Arsenical Compounds / Bruce A. Fowler
  • 14.4. Mechanisms of Arsenical Toxicity / Bruce A. Fowler
  • 14.5. Biomarkers of Nephrotoxicity / Bruce A. Fowler
  • 14.6. Arsenical Interactions with Other Nephrotoxic Elements / Bruce A. Fowler
  • 14.7. Summary and Future Research Needs / Bruce A. Fowler
  • References / Bruce A. Fowler
  • 15.1. Introduction / Weiqun Shu / Jiaohua Luo
  • 15.2. Arsenic Exposure Impairs Intellectual Function in Children / Weiqun Shu / Jiaohua Luo.
  • Note continued: 15.3. Developmental Neurobehavioral Toxicity in Animals / Jiaohua Luo / Weiqun Shu
  • 15.4. Arsenic Distribution After Exposure in Early Life / Jiaohua Luo / Weiqun Shu
  • 15.5. Mechanism of Developmental Neurotoxicity / Jiaohua Luo / Weiqun Shu
  • 15.6. Neuroprotective Agents Against Arsenic Toxicity / Weiqun Shu / Jiaohua Luo
  • 15.7. Conclusions / Jiaohua Luo / Weiqun Shu
  • References / Jiaohua Luo / Weiqun Shu
  • 16.1. Introduction / Fengyuan Piao / Shuangyue Li / Huai Guan
  • 16.2. Accumulation of Arsenic in Fetal Brain Tissue / Fengyuan Piao / Huai Guan / Shuangyue Li
  • 16.3. Effect of Arsenic on the Development of the Nervous System / Fengyuan Piao / Shuangyue Li / Huai Guan
  • 16.4. Effect of Arsenic on Neurobehavior / Shuangyue Li / Fengyuan Piao / Huai Guan
  • 16.5. Mechanisms for the Effect of Arsenic on the Nervous System During Development / Fengyuan Piao / Shuangyue Li / Huai Guan.
  • Note continued: 16.6. Conclusions and Future Directions / Fengyuan Piao / Shuangyue Li / Huai Guan
  • References / Fengyuan Piao / Shuangyue Li / Huai Guan
  • 17.1. Introduction / Kathryn A. Bailey / Rebecca C. Fry
  • 17.2. Adverse Health Effects Associated with Chronic and Early-Life Arsenic Exposure / Rebecca C. Fry / Kathryn A. Bailey
  • 17.3. Mechanisms Implicated in Disease Development Associated with Prenatal Exposure / Rebecca C. Fry / Kathryn A. Bailey
  • 17.4. Conclusions and Future Directions / Kathryn A. Bailey / Rebecca C. Fry
  • References / Rebecca C. Fry / Kathryn A. Bailey
  • 18.1. Introduction / Ernesto Sabath
  • 18.2. Arsenic and Renal Disease / Ernesto Sabath
  • 18.3. Arsenic and Bladder Disease / Ernesto Sabath
  • References / Ernesto Sabath
  • 19.1. Introduction / Riyaz Basha / G. Rajarami Reddy
  • 19.2. Toxicity / Riyaz Basha / G. Rajarami Reddy
  • 19.3. Developmental Toxicity / Riyaz Basha / G. Rajarami Reddy.
  • Note continued: 19.4. Conclusions / G. Rajarami Reddy / Riyaz Basha
  • References / Riyaz Basha / G. Rajarami Reddy
  • 20.1. Introduction / Winston Shim / Ashish Mehta / Chrishan J.A. Ramachandra
  • 20.2. Cardiovascular System / Winston Shim / Chrishan J.A. Ramachandra / Ashish Mehta
  • 20.3. Arsenic Effects on Blood / Chrishan J.A. Ramachandra / Ashish Mehta / Winston Shim
  • 20.4. Arsenic Effects on the Vascular System / Ashish Mehta / Chrishan J.A. Ramachandra / Winston Shim
  • 20.5. Arsenic Effects on the Heart / Chrishan J.A. Ramachandra / Winston Shim / Ashish Mehta
  • 20.6. Human Pluripotent Stem Cells: Understanding Arsenic Toxicity / Ashish Mehta / Chrishan J.A. Ramachandra / Winston Shim
  • 20.7. Conclusions / Ashish Mehta / Winston Shim / Chrishan J.A. Ramachandra
  • References / Ashish Mehta / Winston Shim / Chrishan J.A. Ramachandra
  • 21.1. Introduction / Laila N. Islam
  • 21.2. Influence of Nutritional Factors / Laila N. Islam.
  • Note continued: 21.3. Effects on Blood Leukocytes / Laila N. Islam
  • 21.4. Interruption of Energy Production / Laila N. Islam
  • 21.5. Effects on ROS Production / Laila N. Islam
  • 21.6. Genotoxic and Carcinogenic Potentials / Laila N. Islam
  • 21.7. Hematological Effects on Experimental Animals / Laila N. Islam
  • 21.8. Effects on Heme Synthesis / Laila N. Islam
  • 21.9. Hepatic Effects and Lipid Peroxidation / Laila N. Islam
  • 21.10. Effects on Immune Responses in Fish / Laila N. Islam
  • 21.11. Effects on Immune Responses in Laboratory Animals / Laila N. Islam
  • 21.12. Effects of Arsenic in Drinking Water on Human Health / Laila N. Islam
  • 21.13. Immunotoxic Effects of Organic Arsenicals in Foods / Laila N. Islam
  • 21.14. Medicinal Use of Arsenic and Its Mechanism of Action / Laila N. Islam
  • 21.15. Effects of Arsenic Compounds on Human Cells in Culture / Laila N. Islam
  • 21.16. Immunotoxic Effects on Murine and Human Monocytes/Macrophages / Laila N. Islam.
  • Note continued: 21.17. Immunotoxic Effects on Murine Mononuclear Cells / Laila N. Islam
  • 21.18. Decreased Cytokine Production by Human T Cells / Laila N. Islam
  • 21.19. Effects of In Utero Exposure on Infant Immune System / Laila N. Islam
  • 21.20. Gender-Related Immunotoxic Effects in Human / Laila N. Islam
  • 21.21. Effects of Chronic Exposure on Immune Response / Laila N. Islam
  • 21.22. Association with Respiratory Complications and Impaired Immune Responses / Laila N. Islam
  • 21.23. Effects of Chronic Exposure on Serum Complement Function / Laila N. Islam
  • 21.24. Conclusions / Laila N. Islam
  • References / Laila N. Islam
  • 22.1. Introduction / Molly L. Kile / Maitreyi Mazumdar
  • 22.2. Developmental Toxicity / Molly L. Kile / Maitreyi Mazumdar
  • 22.3. Reproductive Toxicity / Molly L. Kile / Maitreyi Mazumdar
  • 22.4. Early-Life Exposures and Delayed Health Effects / Molly L. Kile / Maitreyi Mazumdar
  • 22.5. Reproductive Disorders / Molly L. Kile / Maitreyi Mazumdar.
  • Note continued: 22.6. Conclusions / Molly L. Kile / Maitreyi Mazumdar
  • References / Maitreyi Mazumdar / Molly L. Kile
  • 23.1. Arsenic and Arsenic-Containing Compounds / Paul B. Tchounwou / Udensi K. Udensi / Sanjay Kumar / Clement G. Yedjou / Raphael D. Isokpehi
  • 23.2. Sources of Arsenic and Potential for Human Exposure / Paul B. Tchounwou / Udensi K. Udensi / Sanjay Kumar / Clement G. Yedjou / Raphael D. Isokpehi
  • 23.3. Molecular Mechanisms of Arsenic-Induced Carcinogenesis / Paul B. Tchounwou / Udensi K. Udensi / Sanjay Kumar / Clement G. Yedjou / Raphael D. Isokpehi
  • 23.4. Health Effects Associated with Arsenic Exposure / Paul B. Tchounwou / Udensi K. Udensi / Sanjay Kumar / Clement G. Yedjou / Raphael D. Isokpehi
  • 23.5. Conclusions / Paul B. Tchounwou / Udensi K. Udensi / Sanjay Kumar / Clement G. Yedjou / Raphael D. Isokpehi
  • Acknowledgments / Paul B. Tchounwou / Udensi K. Udensi / Sanjay Kumar / Clement G. Yedjou / Raphael D. Isokpehi.
  • Note continued: References / Paul B. Tchounwou / Udensi K. Udensi / Sanjay Kumar / Clement G. Yedjou / Raphael D. Isokpehi
  • 24.1. Introduction / Bayzidur Rahman / Tanvir Abir / Abul Hasnat Milton / Md. Rafiqul Islam / AKM Akbar Hossain
  • 24.2. Methods and Materials / Bayzidur Rahman / Tanvir Abir / Abul Hasnat Milton / Md. Rafiqul Islam / AKM Akbar Hossain
  • 24.3. Results / Bayzidur Rahman / Tanvir Abir / Abul Hasnat Milton / Md. Rafiqul Islam / AKM Akbar Hossain
  • 24.4. Discussion / Bayzidur Rahman / Tanvir Abir / Abul Hasnat Milton / Md. Rafiqul Islam / AKM Akbar Hossain
  • References / Bayzidur Rahman / Tanvir Abir / Abul Hasnat Milton / Md. Rafiqul Islam / AKM Akbar Hossain
  • 25.1. Arsenic: The Toxic Metalloid / Manel del Valle / Minni Singh
  • 25.2. Arsenic Biosensors / Manel del Valle / Minni Singh
  • 25.3. Nanosensor Platforms[--]Towards High-Throughput Detection / Manel del Valle / Minni Singh.
  • Note continued: 25.4. Conclusions and Future Directions / Manel del Valle / Minni Singh
  • References / Manel del Valle / Minni Singh
  • 26.1. Introduction / Govinder Flora / Swaran J.S. Flora / Megha Mittal
  • 26.2. Clinical Aspects of Arsenic / Govinder Flora / Swaran J.S. Flora / Megha Mittal
  • 26.3. Diagnosis / Govinder Flora / Swaran J.S. Flora / Megha Mittal
  • 26.4. Chelation Therapy / Govinder Flora / Swaran J.S. Flora / Megha Mittal
  • 26.5. Chelators in Clinical Use / Govinder Flora / Megha Mittal / Swaran J.S. Flora
  • 26.6. Analogues of DMSA as Potential New Arsenic Chelators / Govinder Flora / Swaran J.S. Flora / Megha Mittal
  • 26.7. Role of Antioxidants in Preventing Arsenic Toxicity / Govinder Flora / Swaran J.S. Flora / Megha Mittal
  • 26.8. Newer Strategies / Govinder Flora / Swaran J.S. Flora / Megha Mittal
  • 26.9. Concluding Remarks and Future Directions / Govinder Flora / Swaran J.S. Flora / Megha Mittal.
  • Note continued: References / Govinder Flora / Swaran J.S. Flora / Megha Mittal
  • 27.1. Introduction / Sarita Pandey / Lal Chand Rai / Rashmi Rai
  • 27.2. Arsenic Toxicity and Tolerance in Microbes / Rashmi Rai / Sarita Pandey / Lal Chand Rai
  • 27.3. Arsenic Toxicity and Tolerance in plants / Sarita Pandey / Lal Chand Rai / Rashmi Rai
  • 27.4. Mechanisms of Arsenic Tolerance and Detoxification / Sarita Pandey / Lal Chand Rai / Rashmi Rai
  • 27.5. As Hyperaccumulation and Phytoextraction / Sarita Pandey / Lal Chand Rai / Rashmi Rai
  • 27.6. Summary Points / Sarita Pandey / Lal Chand Rai / Rashmi Rai
  • Acknowledgments / Sarita Pandey / Lal Chand Rai / Rashmi Rai
  • References / Sarita Pandey / Lal Chand Rai / Rashmi Rai
  • 28.1. Introduction / Devang B. Khambholja / Kiran Kalia
  • 28.2. Arsenic Concentration in Sea Water / Devang B. Khambholja / Kiran Kalia
  • 28.3. Arsenic Concentration in Marine Sediments / Devang B. Khambholja / Kiran Kalia.
  • Note continued: 28.4. Arsenic Speciation in Marine Ecosystems / Devang B. Khambholja / Kiran Kalia
  • 28.5. Arsenic Cycle in the Marine Environment / Devang B. Khambholja / Kiran Kalia
  • 28.6. Role of Marine Biological Systems in Arsenic Biotransformation / Devang B. Khambholja / Kiran Kalia
  • 28.7. Arsenic in Seafood and Its Toxicity / Devang B. Khambholja / Kiran Kalia
  • 28.8. Future Directions / Devang B. Khambholja / Kiran Kalia
  • References / Devang B. Khambholja / Kiran Kalia.