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Cognitive enhancement : pharmacologic, environmental and genetic factors /
Cognitive Enhancement: Pharmacologic, Environmental and Genetic Factors addresses the gap that exists in research on the topic, gathering multidisciplinary knowledge and tools that help the reader understand the basics of cognitive enhancement. It also provides assistance in designing procedures and...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam :
Elsevier,
[2015]
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Cognitive Enhancement; Copyright; Dedication; Contents; Contributors; Chapter 1
- What Is Cognitive Enhancement?; GENERAL DEFINITION OF COGNITIVE ENHANCEMENT; DIFFERENT CLASSES OF COGNITIVE ENHANCEMENT; LIFESTYLE USE VERSUS THERAPEUTIC USE OF COGNITIVE ENHANCERS; THE ASPECTS OF COGNITION BEING ENHANCED; ARE TODAY'S "COGNITIVE ENHANCERS" TRULY EFFICIENT?; POSSIBLE RISKS IN THE USE OF COGNITIVE ENHANCERS; A JOURNEY THROUGH THIS BOOK; REFERENCES; Chapter 2
- Signaling Pathways Involved in Cognitive Enhancement; INTRODUCTION; STRESS AS A COGNITIVE ENHANCER
- BIOCHEMICAL SIGNALING PATHWAYS IN LEARNINGBIOCHEMICAL SIGNALING PATHWAYS IN NEURONAL REPAIR; DISADVANTAGES OF COGNITIVE ENHANCERS; CHALLENGES IN DEVELOPING COGNITIVE ENHANCERS; REFERENCES; Chapter 3
- Molecular Mechanisms of Drug-Induced Cognitive Enhancement; INTRODUCTION; TARGETING THE INDUCTION OF PLASTICITY: GLYCINE, D-SERINE; INTERPLAY BETWEEN CELL ADHESION AND GROWTH FACTOR SIGNALING: FGL; MODIFYING SYNAPSES WITH THE "HUNGER HORMONE" GHRELIN; PROLONGING AMPA RECEPTOR EXCITATION: AMPAKINES; REFERENCES; Chapter 4
- Role of Environment, Epigenetics, and Synapses in Cognitive Enhancement
- SETTING THE SCENEEPIGENETIC REGULATION OF THE GENOME; EPIGENETIC SIGNALING AND BEHAVIORAL PLASTICITY; LEARNING AND MEMORY AND SYNAPSE PLASTICITY; NEURODEVELOPMENTAL PRINCIPLES AND MEMORY-RELATED SYNAPSE REMODELING; ROLE OF CELL ADHESION MOLECULES IN EXPERIENCE-DEPENDENT SYNAPSE REMODELING; REGULATION OF NCAM POLYSIALYLATION STATE; REGULATION OF NCAM PSA EXPRESSION DURING ACTIVITY-DEPENDENT NEURAL REMODELING; SYNAPSE REMODELING AND MEMORY CONSOLIDATION; FINAL COMMENT; REFERENCES; Chapter 5
- Transgenic Mice with Enhanced Cognition; GENERATING MUTANT MICE; SYNAPTIC PLASTICITY AND MEMORY
- ENHANCING COGNITION BY AUGMENTING NMDA RECEPTOR FUNCTIONCAMP-CREB SIGNALING; TRANSLATIONAL REGULATION AND ENHANCED COGNITION; EPIGENETIC REGULATION AND ENHANCED COGNITION; REDUCING INHIBITION AND ENHANCED COGNITION; MICRORNA AND ENHANCED COGNITION; EXTRACELLULAR FACTORS AND ENHANCED COGNITION; CONCLUSION; ACKNOWLEDGMENT; REFERENCES; Chapter 6
- The Use of Viral Vectors to Enhance Cognition; INTRODUCTION; ADENO-ASSOCIATED VIRUS; STRATEGIES TO INCREASE EFFICIENCY AND SPECIFICITY OF GENE TRANSFER; TRANS-SPLICING AAV; ADVANCEMENTS IN RAAV PACKAGING AND PURIFICATION; GENE DELIVERY TO THE CNS
- COGNITIVE ENHANCEMENT AND NEUROGENESISNEUROGENESIS IN AGING AND AD; ANIMAL MODELS OF AD; ASSESSING OUTCOMES OF AD GENE THERAPY: BEHAVIORAL TESTING AND NEUROPHYSIOLOGY; CURRENT AAV THERAPIES IN AD ANIMAL STUDIES AND CLINICAL TRIALS; FUTURE DIRECTIONS; REFERENCES; Chapter 7
- Advancing Fear Memory Research with Optogenetics; INTRODUCTION; CONTEMPORARY AND TRADITIONAL METHODS IN MEMORY RESEARCH; NOVEL FINDINGS IN MEMORY RESEARCH FROM OPTOGENETIC STUDIES; MEMORY GENERATION AND MEMORY ENHANCEMENT USING OPTOGENETICS; REFERENCES; Chapter 8
- Can Stem Cells Be Used to Enhance Cognition?; INTRODUCTION