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The biochemistry of poliomyelitis viruses : a synopsis of poliomyelitis infection and research /
The Biochemistry of Poliomyelitis Viruses deals with the interrelationships and differences of positions in the field of poliomyelitis research. This volume presents a general introduction to viruses as to their descriptions and biological, biochemical, and epidemiological aspects. Clinical poliomye...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York :
The Macmillan Company,
1964.
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| Colección: | International series of monographs on pure and applied biology. Division, Modern trends in physiological sciences ;
v. 21. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; The Biochemistry of Poliomyelitis Viruses; Copyright Page ; Table of Contents; FOREWORD; ACKNOWLEDGEMENTS; CHAPTER 1. THE VIRUSES ; A. Virus in older definitions; B. Virus as it looks now; References to Chapter 1; CHAPTER 2. THE BIOLOGICAL, BIOCHEMICAL AND EPIDEMIOLOGICAL ASPECTS OF POLIOMYELITIS OF MAN AND ANIMALS; 1. General notions; 2. Clinical poliomyelitis; 3. Biochemical aspects; References to Chapter 2; CHAPTER 3. EXPERIMENTAL POLIOMYELITIS; 1. The disease in animals; 2. Isolation of the poliomyelitis virus and its bioassay
- Some Aspects of the Immunology and Serology of PoliovirusReferences to Chapter 3; CHAPTER 4. BIOCHEMICAL DATA ON POLIOVIRUS; Purification, crystallization, biochemical and biophysical characterization of poliomyelitis viruses; References to Chapter 4; CHAPTER 5. BIOCHEMISTRY OF ANIMAL-ADAPTED POLIOMYELITIS INFECTION, in Vivo; Introduction; Respiration and glycolysis; Phosphate metabolism and change in the activity of oxidative enzymes; Biochemical data of chromatolytic neurons and virus infected tissues; Further intracellular localization of virus growth; The role of nutrition and co-factors
- The application of enzyme inhibitorsEnvironmental conditions and conditional factors; Effect of hormones; Data on the effect of X-ray radiation, physical and chemical agents; References to Chapter 5; CHAPTER 6. FURTHER CONSIDERATIONS OF THE GENERAL BIOLOGY, BIOCHEMISTRY AND PATHOLOGY OF EXPERIMENTAL POLIOMYELITIS INFECTION IN ANIMALS; 1. Nucleic acid of the host and the virus during experimental poliomyelitis, in vivo; 2. Complementary data on the biology of animal infection; References to Chapter 6; CHAPTER 7. THE HOST CELLS IN GENERAL; 1. General properties of the cells in culture in vitro
- 2. Light microscopic cytopathic changes due to the poliovirus infection3. Some facts on the cellular organization as revealed by ultrastructural research; References to Chapter 7; CHAPTER 8. SOME CYTOLOGICAL AND BIOLOGICAL EFFECTS OF POLIOMYELITIS VIRUS ON CELLS IN CULTURE; 1. General notions; 2. Changes in cell morphology; 3. General biological observations and use of special techniques; References to Chapter 8; CHAPTER 9 . BIOCHEMISTRY OF POLIOVIRUS INFECTION IN CELLS IN CULTURE; General notions, respiration and glycolysis; References to Chapter 9
- CHAPTER 10. CHANGE IN THE PHYSIOLOGY OF CELLS DURING POUOVIRUS INFECTION, in vitro1. Further data on biochemical and especially enzyme changes in the host cells; 2. Early irreversible enzyme alterations leading to the destruction of the host; 3. The influence of hormones and other biological agents administered in vitro; References to Chapter 10; CHAPTER 11. THE ROLE OF HEREDITY; 1. Genetic aspects of clinical and experimental poliomyelitis; 2. Virus genetics; 3. Hypotheses on the biochemical mechanism of heredity; References to Chapter 11