Cargando…

International review of cell and molecular biology /

International Review of Cell and Molecular Biology presents comprehensive reviews and current advances in cell and molecular biology. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation an...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Jeon, Kwang W. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam : Academic Press, 2015.
Colección:International Review of Cell and Molecular Biology ; 314
Temas:
Acceso en línea:Texto completo
Texto completo
Tabla de Contenidos:
  • Front Cover; International Review of Cell and Molecular Biology; International Review of Cell and Molecular Biology; International Review of Cell and Molecular BiologyEdited by KWANG W. JEONDepartment of Biochemistry University of TennesseeK ... ; Copyright ; Contents; Contributors; How Rab Proteins Determine Golgi Structure; 1. Introduction; 2. Rab Proteins and Their Subfamilies; 3. Golgi Apparatus and Its Organization; 4. Two Major Functional/Phenotypic Classes of Rab Proteins Based on Their Effects on Golgi Ribbon Organization.
  • 5. Mechanistic Effect of Rab Proteins on Golgi Ribbon Organization5.1 General Mechanistic Predictions; 5.2 Rab6 and the Role of Individual Effectors; 5.3 Role of Rab33b in Rab6-Dependent Golgi Ribbon Organization; 5.4 Opposing Effects of Rab41 and Rab6 on Golgi Ribbon Organization; 6. Conclusions and Perspectives; Acknowledgments; References; Amyotrophic Lateral Sclerosis as a Spatiotemporal Mislocalization Disease: Location, Location, Location; 1. Introduction; 2. Amyotrophic Lateral Sclerosis; 2.1 Models for ALS Research; 3. Axonal Transport; 3.1 Axonal Cytoskeleton; 3.2 Motor Proteins.
  • 3.3 Mitochondrial Transport4. RNA-Binding Proteins; 4.1 Tar DNA-Binding Protein 43; 4.2 Fused in Sarcoma; 4.3 MicroRNA and RBP; 4.4 Chromosome 9 Open Reading Frame 72; 5. Neurotrophic Factors and Their Precursor Forms; 6. Death Signals; 6.1 p75 Neurotrophin Receptor; 6.2 Death Receptor 6; 6.3 Fas; 6.4 Semaphorins; 7. Amyloid Precursor Protein; 8. Concluding Remarks; Acknowledgments; References; Malleable Mitochondrion of Trypanosoma brucei; 1. Introduction; 2. Maintenance and Expression of Genetic Information; 2.1 kDNA Replication and Maintenance; 2.2 Mitochondrial RNA Metabolism.
  • 2.2.1 Transcription2.2.2 RNA processing; 2.2.3 RNA editing; 2.2.4 RNA turnover; 2.2.5 Mitochondrial tRNA import and modifications; 2.3 Translation and Ribosomes; 3. Mitochondrial Import; 3.1 Protein Import and Processing; 3.2 Transport of Metabolites; 3.3 Transport of Ions; 4. Mitochondrial Metabolism; 4.1 Carbohydrate Metabolism-Krebs Cycle; 4.2 Oxidative Phosphorylation; 4.3 Fatty Acid Biosynthesis; 4.4 Metabolism of Amino Acids; 4.5 Metabolism of Cofactors; 4.5.1 Heme metabolism; 4.5.2 Fe-S cluster and protein biogenesis; 5. Structural Proteins and Fission; 6. Concluding Remarks.
  • AcknowledgmentsReferences; Heredity and Self-Organization: Partners in the Generation and Evolution of Phenotypes; 1. Introduction; 2. Self-Organization in Biology; 2.1 Genes versus Cell Numbers; 2.2 Molecular Self-Organization and DNA; 2.3 Mechanical Forces and Self-Organization; 2.4 Self-Organization of Complex Biological Structures; 2.5 Dynamics; 2.6 Functional Plasticity May Be Based on Self-Organized Processes at Different Biological Scales; 2.7 Dynamics: Self-Organized Component of Developmental Robustness; 3. Internal Descriptions, Developmental Limitations and Buffering Variation.