Cargando…
Studies in natural products chemistry. Volume 44 /
Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam :
Elsevier,
2015.
|
| Colección: | Studies in Natural Products Chemistry ;
44 |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
Tabla de Contenidos:
- Cover; Title Page; Copyright Page; Contents; Contributors; Preface; Chapter 1
- Terpenoids and Sterols from Mushrooms; Introduction; Sesquiterpenoids; Lactarane-Type Sesquiterpenoids; Marasmane-Type Sesquiterpenoids; Nardosinane-Type and Aristolane-Type Sesquiterpenoids; Protoilludane-Type Sesquiterpenoids; Russulane-Type Norsesquiterpenoids; Triterpenoids; Lanostane-Type Triterpenoids; Cucurbitane-Type Triterpenoids; Sterols; Sterols Bearing 5a,6a-Epoxy Group; Sterols Bearing 5a,9a-Epidioxy and 5b,9b-Dihydroxy Groups; Sterols Bearing Enone, Diene, and Ketone Moieties
- Sterols Bearing 3b,5a,6b,7a-Tetrahydroxy, 3b,5a,6a,9a-Tetrahydroxy, and 3b,5a,6b,9a-Tetrahydroxy Groups23-Methylergostane-Type Sterols; Sterols Bearing 1,2,3,4,5,10,19-Heptanor Structure; Meroterpenoids; Conclusions; Abbreviations; References; Chapter 2
- From Bench to Bedside: Natural Products and Analogs for the Treatment of Neglected Tropical Diseases (NTDs); Introduction; Neglected Tropical Diseases; Tuberculosis; Leishmaniasis; Malaria; Chagas Disease (American Trypanosomiasis); Human African Trypanosomiasis (Sleeping Sickness); Dengue; Lymphatic Filariasis (Elephantiasis); Helminthiasis
- Leprosy (Hansen Disease)Trachoma; Buruli Ulcer; Schistosomiasis; Conclusions; Abbreviations; References; Chapter 3
- Febrifugine and Its Analogs: Studies for Their Antimalarial and Other Therapeutic Properties; Introduction; Discovery; Structure Elucidation; Chemical and physical Properties of Febrifugine; Synthesis of Febrifugine; Pharmacology of Febrifugine; Antimalarial Activity of Febrifugine; Anticoccidial Activity; Toxicity; Febrifugine Analogs; Halofuginone; Antimalarial Properties; Coccidiosis; Autoimmune Diseases; Other Diseases; Polypharmacy; Abbreviations; Concluding Remarks
- AcknowledgmentsReferences; Chapter 4
- Macrocyclic N-Methylated Cyclic Peptides and Depsipeptides; Introduction; Aureobasidins; Introduction; Isolation; Classification of Abs; Structural Determination; Biological Activity; Synthesis; Total Synthesis of Abs; Semisynthesis of Abs; Cyclosporins; Introduction; Isolation; Classification of Cs; Structural Determination; Biological Activity; Synthesis; Synthesis of Cyclosporins; Synthesis of Unusual Amino Acid MeBmt; Dolastatin; Introduction; Isolation; Classification of Cyclic Peptides; Cyclopeptides; Cyclodepsipeptides; Structure Determination
- Biological ActivitySynthesis; Didemnins; Introduction; Isolation; Classification of Didemnins; Structural Determination; Biological Activity; Synthesis; Total Syntheses of Didemnin, the Natural Products; Syntheses of Didemnin Analogs; Miscellaneous Cyclopeptides and Cyclodepsipeptide; Introduction; Omphalotins; Petriellin; Clavariopsins; Somamides; Salinamides; Abbreviations; Conclusion; References; Chapter 5
- Anticancer Drugs and Potential Anticancer Leads Inspired by Natural Products; Introduction; Tubulin/Microtubule-Targeted Anticancer Agents