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Advances in genetics. Volume eighty seven /

The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in our knowledge of genetics. Advances in Genetics continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. Volume 87...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Friedmann, Theodore (Editor ), Dunlap, Jay C. (Editor ), Goodwin, Stephen F. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Academic Press, 2014.
Edición:First edition.
Temas:
Acceso en línea:Texto completo
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MARC

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245 0 0 |a Advances in genetics.  |n Volume eighty seven /  |c edited by Theodore Friedmann, Department of Pediatrics, University of California at San Diego, School of Medicine, CA, USA, Jay C. Dunlap, Department of Genetics, the Geisel School of Medicine at Dartmouth, Hanover, NH, USA, Stephen F. Goodwin, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford UK. 
250 |a First edition. 
264 1 |a London :  |b Academic Press,  |c 2014. 
300 |a 1 online resource (313 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
588 0 |a Online resource; title from PDF title page (ebrary, viewed October 22, 2014). 
520 |a The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in our knowledge of genetics. Advances in Genetics continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. Volume 87 presents an eclectic mix of articles of use to all human and molecular geneticists on topics including: gene transfer, fruiting body development and the genetics of Alzheimer's disease; and more. 
505 0 |a Front Cover; Advances in Genetics; Copyright; CONTENTS; CONTRIBUTORS; 1 -- Opportunity for Selection in Human Health; 1. INTRODUCTION; 2. GENETIC VARIATION AND DEMOGRAPHIC SELECTION; 3. EPISODES OF SELECTION; 4. SELECTION SPECTRA; 5. PLACE OF MULTILEVEL SELECTION IN MEDICAL PRACTICE AND PUBLIC HEALTH; 6. DISCUSSION; ACKNOWLEDGMENTS; REFERENCES; 2 -- Clinical Applications Involving CNS Gene Transfer; 1. INTRODUCTION; 2. CNS CLINICAL TRIALS UTILIZING RETROVIRAL VECTORS; 3. CNS CLINICAL TRIALS UTILIZING AAV VECTORS; 4. LESSONS LEARNED FROM RELATED STUDIES; 5. CONCLUSION; REFERENCES 
505 8 |a 3 -- Methods for Gene Transfer to the Central Nervous System1. INTRODUCTION; 2. VECTORS FOR CNS GENE TRANSFER; 3. GENOME DESIGNS FOR OPTIMAL EXPRESSIONS; 4. CONCLUSIONS; REFERENCES; 4 -- The Filamentous Fungus Sordaria macrospora as a Genetic Model to Study Fruiting Body Development; 1. INTRODUCTION; 2. GENETIC AND GENOMIC TOOLS; 3. THE STRIATIN-INTERACTING PHOSPHATASE AND KINASE COMPLEX, A MULTISUBUNIT PROTEIN COMPLEX GOVERNING FRUITING BODY DEVELOPMENT; 4. CHROMATIN-RELATED PROCESSES; 5. METABOLISM-RELATED DEVELOPMENTAL PROCESSES; 6. AUTOPHAGY; 7. CONCLUDING REMARKS AND OUTLOOK 
505 8 |a ACKNOWLEDGMENTSREFERENCES; 5 -- Genetics of Alzheimer's Disease; 1. INTRODUCTION; 2. HERITABILITY OF ALZHEIMER'S DISEASE; 3. GENETIC CAUSES OF EARLY-ONSET ALZHEIMER'S DISEASE; 4. GENETIC RISK FACTORS FOR LATE-ONSET ALZHEIMER'S DISEASE; 5. DISCUSSION; REFERENCES; INDEX 
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700 1 |a Friedmann, Theodore,  |e editor. 
700 1 |a Dunlap, Jay C.,  |e editor. 
700 1 |a Goodwin, Stephen F.,  |e editor. 
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