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Stem cell biology and tissue engineering in dental sciences /

The editors have compiled basic embryology and developmental biology with keen focus on stem cells, basic cell and matrix biology with relevance to tissue regeneration and repair, biomaterials (including nanotechnology) and current applications in various disciplines of dental science.

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Vishwakarma, Ajay (Editor ), Sharpe, Paul (Editor ), Shi, Songtao (Editor ), Wang, Xiu-Ping (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Elsevier Ltd., [2015]
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; Stem Cell Biology and Tissue Engineering in Dental Sciences; Copyright; Contents; List of Contributors; Foreword; Chapter 1: An Introduction to Stem Cell Biology and Tissue Engineering; 1.1. Introduction; 1.2. The emergence of Tissue Engineering and regenerative medicine; 1.3. Research themes underlying Tissue Engineering technology; 1.3.1. Cells; 1.3.2. Biomaterial Scaffolds; 1.3.3. Tissue-Inducing Factors; 1.3.4. Devices and Systems; 1.4. Stem cell-based therapy; 1.4.1. Pure Stem Cell Therapy; 1.4.2. Scaffold-Based Stem Cell Therapy; 1.5. Translational Tissue Engineering.
  • 1.6. ConclusionReferences; Part I: Developmental Biology: A Blueprint for Tissue Engineering; Chapter 2: Developmentally Inspired Regenerative Organ Engineering: Tooth as a Model ; 2.1. Introduction; 2.2. Understanding generation for regeneration strategies: a tooth model; 2.3. Epithelial-mesenchymal interactions during odontogenesis; 2.4. ECM and mechanical forces as regulators of organogenesis; 2.5. Engineering approaches for tooth organ regeneration; 2.6. Conclusion; References; Chapter 3: Extracellular Matrix Molecules; 3.1. Introduction; 3.1.1. Overview.
  • 3.1.2. Extracellular Matrix Proteins3.1.3. Crosslinking; 3.2. Collagens; 3.2.1. Collagen Biosynthesis and Processing; 3.2.2. Fibril-Forming Collagens; 3.2.2.1. Biomineralization; 3.2.3. Fibril-Associated Collagens (FACITs); 3.2.4. Network-Forming Collagens; 3.2.5. Anchoring Fibrils; 3.2.6. Other Collagens; 3.2.7. Collagenopathies; 3.2.7.1. Osteogenesis Imperfecta (OI); 3.2.7.2. Ehlers-Danlos Syndrome; 3.2.7.3. Skeletal Dysplasias and Chondrodysplasias; 3.2.7.4. Other Collagenopathies; 3.3. Glycoproteins; 3.3.1. Fibronectin; 3.3.2. Fibrillins and Latent TGF-�-Binding Proteins (LTBPs)
  • 3.3.2.1. Structural and Functional Properties of Fibrillins and LTBPs3.3.2.2. Fibrillinopathies; 3.3.3. Fibulins; 3.3.4. Other Glycoproteins; 3.3.4.1. Tenascin; 3.3.4.2. The Small Integrin-Binding Ligand N-Linked Glycoproteins (SIBLINGs); 3.3.4.3. Thrombospondins; 3.4. Elastin and Elastic Fibers; 3.4.1. Elastic Fiber Assembly; 3.4.2. Elastin-Associated Pathologies; 3.5. Basement Membranes; 3.5.1. Laminins; 3.5.2. Collagen Type IV; 3.5.3. Basement Membrane Proteoglycans; 3.5.4. Basement Membrane-Associated Pathologies; 3.6. Proteoglycans and Glycosaminoglycans; 3.6.1. Glycosaminoglycans.
  • 3.6.2. Proteoglycans3.6.2.1. Cell Surface Proteoglycans; 3.6.2.2. Modular Proteoglycans; 3.6.2.3. Small Leucine Rich Proteoglycans (SLRPs); 3.7. Concluding Remarks; Acknowledgments; Abbreviations; References; Chapter 4: Cell-Matrix Interactions and Signal Transduction; 4.1. Introduction; 4.1.1. The First Evidence that Matrices Change Cell Behavior; 4.1.2. Integrin and Non-Integrin Receptor Discovery; 4.2. Receptors; 4.2.1. Integrins: Mediators of Cell-Matrix Interactions; 4.2.1.1. Integrin a Subunits; 4.2.1.2. Integrin � Subunits; 4.2.2. Non-Integrin Receptors for ECM Molecules.