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Determination of beta-blockers in biological material /
This is the third volume of a sub-series entitled Evaluation of Analytical Methods in Biological Systems. (The first two were Analysis of Biogenic Amines edited by G.B. Baker and R.T. Coutts, and Hazardous Metals in Human Toxicology edited by A. Vercruysse). This latest volume addresses beta-blocker...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam :
Elsevier,
1989.
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| Colección: | Techniques and instrumentation in analytical chemistry ;
v. 4, pt. C. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
Tabla de Contenidos:
- Front Cover; Determination of Beta-Blockers in Biological Material; Copyright Page; Table of Contents; List of contributors; PREFACE; INTRODUCTION; REFERENCES; CHAPTER 1. RECENT DEVELOPMENTS IN THE CLINICAL PHARMACOLOGY OF �-BLOCKERS; 1.1 INTRODUCTION; 1.2 CLINICAL PHARMACOLOGY PROPERTIES; 1.3 THE PHARMACOKINETICS OF � -ANTAGONISTS; REFERENCES; CHAPTER 2. CLINICAL PHARMACOKINETICS OF BETA-BLOCKERS; 2.1 INTRODUCTION; 2.2 BASIC INFORMATION ON PHYSICO-CHEMICAL PROPERTIES AND PHARMACOKINETICS OF BETA-BLOCKERS; 2.3 BLOOD LEVELS OF BETA-BLOCKERS.
- 2.4 correlation between pharmacokinetic and pharmacodynamic response2.5 elimination kinetics of beta-adrenoceptor blocking drugs; 2.6 chronopharmacokinetics of beta-blockers; 2.7 alterations in the pharmacokinetics of beta-blockers during chronic regimens; 2.8 polymorphic oxidation of beta-blockers; 2.9 stereoselective disposition of beta-blockers in man; 2.10 inter- and intra-subject variability of the pharmacokinetics of beta-bockers; 2.11 pharmacokinetics of beta-blockers in pregnancy; 2.12 placental transfer of beta-blockers; 2.13 excretion of beta-blockers into human breast milk.
- 2.14 effect of food on the plasma level of beta-blockers2.15 pharmacokinetics of beta-blockers in elderly subjects; 2.16 effect of disease on the clinical pharmacokinetics of betablockers; 2.17 interaction of drugs with the pharmacokinetics of beta-blockers; 2.18 pharmacokinetics op slow-release formulations; references; chapter 3. sample pretreatment in the determination of beta-blockers in biological fluids; 3.1 introduction; 3.2 structure of beta-blockers; 3.3 biological fluids; 3.4 preparation of the analytical sample; 3.5 future perspectives; references.
- CHAPTER 4. DETERMINATION OF BETA-BLOCKERS BY OPTICAL METHODS4.1 INTRODUCTION; 4.2 SPECTROPHOTOMETRIC PROPERTIES OF BETA-BLOCKERS; 4.3 OPTICAL METHODS; 4.4 VALIDITY OF SPECTROFLUOROMETRY; REFERENCES; CHAPTER 5.1 GAS-LIQUID CHROMATOGRAPHY OF BETA-BLOCKERS; 5.1.1 INTRODUCTION; 5.1.2. DERIVATIZATION OF �-BLOCKERS FOR GAS CHROMATOGRAPHY; 5.1.3 �-BLOCKERS AND THE GAS-CHROMATOGRAPHIC COLUMN; 5.1.4. DETECTION; 5.1.5. CHOOSING COLUMN DIMENSIONS; 5.1.6 SAMPLE INTRODUCTION; 5.1.7 COMPARISON OF DIFFERENT GLC METHODS; ACKNOWLEDGEMENTS; REFERENCES.