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Medicinal chemistry-III : main lectures presented at the third International Symposium on Medicinal Chemistry held in Milan, Italy, 13-15 September 1972 /
Medicinal Chemistry-III provides information pertinent to the fundamental aspects of medicinal chemistry. This book discusses the mechanism of action of drugs at the molecular level. Organized into eight chapters, this book begins with an overview of the systems for protein biosynthesis that are cla...
| Clasificación: | Libro Electrónico |
|---|---|
| Autores Corporativos: | , |
| Otros Autores: | |
| Formato: | Electrónico Congresos, conferencias eBook |
| Idioma: | Inglés |
| Publicado: |
London :
Butterworths,
1973.
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 003 | OCoLC | ||
| 005 | 20231120111847.0 | ||
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| 007 | cr cnu---unuuu | ||
| 008 | 141029s1973 enka ob 100 0 eng d | ||
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| 019 | |a 895435183 | ||
| 020 | |a 9781483284743 |q (electronic bk.) | ||
| 020 | |a 1483284743 |q (electronic bk.) | ||
| 020 | |z 9780408705387 | ||
| 035 | |a (OCoLC)893979370 |z (OCoLC)895435183 | ||
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| 111 | 2 | |a International Symposium on Medicinal Chemistry |n (3rd : |d 1972 : |c Milan, Italy) | |
| 245 | 1 | 0 | |a Medicinal chemistry-III : |b main lectures presented at the third International Symposium on Medicinal Chemistry held in Milan, Italy, 13-15 September 1972 / |c symposium editor: P. Pratesi ; [sponsored by] International Union of Pure and Applied Chemistry, Organic Chemistry Division. |
| 264 | 1 | |a London : |b Butterworths, |c 1973. | |
| 300 | |a 1 online resource (6 unnumbered pages, pages 353-522) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 500 | |a Added title page in French: Chimie medicinale-III. | ||
| 500 | |a Simultaneously published in Pure and Applied Chemistry, vol. 35, no. 4, 1973. | ||
| 504 | |a Includes bibliographical references. | ||
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a Front Cover; Medicinal Chemistry-III; Copyright page; Table of Contents; OPENING REMARKS; CHAPTER 1. THE MECHANISMS OF SELECTIVITY AND ACTIONOF PROTEIN SYNTHESIS INHIBITORS; ABSTRACT; THE MECHANISM OF PROTEIN SYNTHESIS; SELECTIVITY OF PROTEIN SYNTHESIS INHIBITORS; RIBOSOME SUBUNITS AS SPECIFIC TARGETS OF ANTIBIOTIC ACTION; INHIBITORS OF THE INITIATION PHASE; INHIBITORS OF THE ELONGATION CYCLE; REFERENCES; CHAPTER 2. THE SIGNIFICANCE OF D-ALANYL-D-ALANINE TERMINI IN THE BIOSYNTHESIS OF BACTERIAL CELL WALLS AND THE ACTION OF PENICILLIN, VANCOMYCIN AND RISTOCETIN; ABSTRACT; INTRODUCTION. | |
| 505 | 8 | |a PENICILLINVANCOMYCIN AND RISTOCETIN; COMPETITION FOR VANCOMYCIN BINDING SITES; CONCLUSION; REFERENCES; CHAPTER 3. INHIBITORS OF THE TRANSCRIBING ENZYMES; ABSTRACT; INTRODUCTION; TRANSCRIPTASE (DNA-DEPENDENT RNA POLYMERASE): STRUCTURE AND FUNCTION; SPECIFIC INHIBITORS OF TRANSCRIPTASE; STRUCTURAL MODIFICATIONS OF THE RIFAMYCINS ANDTHEIR EFFECT ON ANTIBACTERIAL ACTIVITY; ACTIVITY OF RIFAMYCINS ON VIRAL TRANSCRIPTASES; ACKNOWLEDGMENT; REFERENCES; CHAPTER 4. ANALOGUES OF CYCLIC AMP AND THEIRPHYSIOLOGICAL RESPONSE; ABSTRACT; THE SECOND MESSENGER MODEL; THE cAMP-SYSTEM; cAMP-ANALOGUES. | |
| 505 | 8 | |a GLYCOGENOLYSISSTEROIDOGENESIS; LIPOLYSIS; SECRETION OF PITUITARY HORMONES; EFFECTS OF cAMP-ANALOGUES ON CONTRACTILE TISSUES; PHARMACOLOGICAL ASPECTS; REFERENCES; CHAPTER 5. PRINCIPLES OF NEUROCHEMISTRY AND DRUG SCREENING PROCEDURES INNEUROPSYCHOPHARMACOLOGY; ABSTRACT; INTRODUCTION; THE CONCEPT OF POSTSYNAPTIC RECEPTOR IN DRUG DEVELOPMENT; REFERENCES; CHAPTER 6. ACTIVE POLYPEPTIDES OF THE AMPHIBIAN SKINAND THEIR SYNTHETIC ANALOGUES; ABSTRACT; INTRODUCTION; PHYSALAEMIN-LIKE PEPTIDES; BRADYKININ-LIKE PEPTIDES; CAERULEIN-LIKE PEPTIDES; BOMBESIN-LIKE PEPTIDES; MISCELLANEOUS POLYPEPTIDES. | |
| 505 | 8 | |a Discussionacknowledgements; references; chapter 7. some biological applications of regularsolution theory; abstract; introduction; historical foundations; models for the analysis of biological activities; formulation in terms of regular solution theory; application to studies of erythrocyte haemolysis; conclusions; references; chapter 8. the prediction of molecular conformation as a biologicallysignificant property; abstract; introduction; evaluation of conformation; molecular orbital prediction of conformation; muscarinic agents; nicotinic agents; histamine; serotonin; pregnane steroids. | |
| 505 | 8 | |a Adrenergic agentsdopamine; central inhibitory transmitters; prostaglandin; peptide hormones; sweet taste pharmacophore; conclusion; references; concluding remarks. | |
| 520 | |a Medicinal Chemistry-III provides information pertinent to the fundamental aspects of medicinal chemistry. This book discusses the mechanism of action of drugs at the molecular level. Organized into eight chapters, this book begins with an overview of the systems for protein biosynthesis that are classified according to their mechanism and the selective action of drugs on their reactions. This text then examines the key structure in the biosynthesis of the peptidoglycans of bacterial cell walls. Other chapters consider the enzymes that transcribe DNA synthesizing RNA, which have structural diff. | ||
| 650 | 0 | |a Pharmaceutical chemistry |v Congresses. | |
| 650 | 0 | |a Pharmaceutical chemistry. | |
| 650 | 2 | |a Chemistry, Pharmaceutical |0 (DNLM)D002626 | |
| 650 | 6 | |a Chimie pharmaceutique |0 (CaQQLa)201-0028674 |v Congr�es. |0 (CaQQLa)201-0378219 | |
| 650 | 6 | |a Chimie pharmaceutique. |0 (CaQQLa)201-0028674 | |
| 650 | 7 | |a MEDICAL |x Pharmacology. |2 bisacsh | |
| 650 | 7 | |a Pharmaceutical chemistry |2 fast |0 (OCoLC)fst01060115 | |
| 655 | 2 | |a Congress |0 (DNLM)D016423 | |
| 655 | 7 | |a proceedings (reports) |2 aat |0 (CStmoGRI)aatgf300027316 | |
| 655 | 7 | |a Conference papers and proceedings |2 fast |0 (OCoLC)fst01423772 | |
| 655 | 7 | |a Conference papers and proceedings. |2 lcgft | |
| 655 | 7 | |a Actes de congr�es. |2 rvmgf |0 (CaQQLa)RVMGF-000001049 | |
| 700 | 1 | |a Pratesi, P., |e editor. | |
| 710 | 2 | |a International Union of Pure and Applied Chemistry. |b Organic Chemistry Division. | |
| 776 | 0 | 8 | |i Print version: |a International Symposium on Medicinal Chemistry (3rd : 1972 : Milan). |t Medicinal chemistry-III |z 0408705388 |w (DLC) 74594813 |w (OCoLC)1145062 |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780408705387 |z Texto completo |