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Molecular genetic medicine. Volume 3 /
Molecular Genetic Medicine, Volume III, summarizes progress in several of the most important areas of modern molecular genetics and medicine. The book opens with a chapter on the birth and early development of the field of human gene therapy and the earliest conceptual and technical descriptions of...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego :
Academic Press,
[1993]
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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|---|---|---|---|
| 001 | SCIDIR_ocn893978733 | ||
| 003 | OCoLC | ||
| 005 | 20231120111847.0 | ||
| 006 | m o d | ||
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| 019 | |a 895434036 |a 906928558 |a 1162060989 | ||
| 020 | |a 9781483276052 |q (electronic bk.) | ||
| 020 | |a 1483276058 |q (electronic bk.) | ||
| 020 | |z 9780124620032 | ||
| 020 | |z 0124620035 | ||
| 035 | |a (OCoLC)893978733 |z (OCoLC)895434036 |z (OCoLC)906928558 |z (OCoLC)1162060989 | ||
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| 082 | 0 | 4 | |a 616/.042 |2 23 |
| 245 | 0 | 0 | |a Molecular genetic medicine. |n Volume 3 / |c edited by Theodore Friedmann. |
| 264 | 1 | |a San Diego : |b Academic Press, |c [1993] | |
| 264 | 4 | |c �1993 | |
| 300 | |a 1 online resource (xii, 242 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a Front Cover; Molecular Genetic Medicine; Copyright Page; Table of Contents; Contributors; Preface; Chapter 1. Milestones and Events in the Early Development of Human Gene Therapy; I. Phase 1. Prior to 1970: Genetically Marked Cells and DNA-Mediated Transformation; II. Phase 2. The Cline Experiment, Efficient Vectors, in Vitro Models, and the Maturing Ethical and Public Policy Debate; III. Phase 3. The Regulatory Process and the First Direct Clinical Applications: The Recombinant Advisory Committee (RAC), Its Gene Therapy Subcommittee, and the Food and Drug Administration (FDA); Acknowledgment. | |
| 505 | 8 | |a IX. A Clonal Evolution Model for Astrocytic TumorsX. Testing the Genetic Model; XI. Conclusion; References; Chapter 4. Molecular Biology of Alzheimer's Disease; I. Introduction; II. History; III. Epidemiology; IV. Genetics; V. Clinical and Neuropsychological Features; VI. Diagnosis; VII. Treatment; VIII. Nerve Growth Factor and Related Molecules in the Central Nervous System; IX. Central Actions of Nerve Growth Factor; X. NGF-Related Trophic Factors: The Neurotrophins; XI. Neurotrophin Receptors; XII. NGF Mechanism of Action; XIII. A Model of Trophic Factor Action in Neurodegenerative Disease. | |
| 505 | 8 | |a XIV. Molecular NeuropathologyXV. Amyloid Deposition in Alzheimer's Disease; XVI. �APP Processing; XVII. Conclusion: Clinical and Societal Implications; References; Chapter 5. Hunting for Huntington's Disease; I. Introduction; II. Finding a Landmark near HD; III. Which Way to the Prey?; IV. Physical Layout of the Search Area; V. Tools for Tracking; VI. Limiting the Hunt Using Crossovers in Disease Pedigrees; VII. The Historical Trail of HD in Allele Associations; VIII. What Is the Nature of the Quarry?; Acknowledgments; References; Note Added in Proof: Hunting's Done! | |
| 505 | 8 | |a Chapter 6. Genetics, Insurance, and the Ethics of Genetic CounselingI. Introduction: Genetic Prediction and the Challenge to Insurance; II. Health Insurance; III. Life Insurance; IV. Ethical Conflicts of Providers of Genetic Services; V. Conclusion; References; Index. | |
| 520 | |a Molecular Genetic Medicine, Volume III, summarizes progress in several of the most important areas of modern molecular genetics and medicine. The book opens with a chapter on the birth and early development of the field of human gene therapy and the earliest conceptual and technical descriptions of the issues and opportunities in this new area of medicine. This is followed by separate chapters on the gene responsible for cystic fibrosis; interactions and genetic phenomena that accompany the progression of astrocytic tumors; and molecular biology of Alzheimer's disease; and the search for the. | ||
| 546 | |a English. | ||
| 650 | 0 | |a Medical genetics. | |
| 650 | 0 | |a Human molecular genetics. | |
| 650 | 2 | |a Genetics, Medical |0 (DNLM)D005826 | |
| 650 | 2 | |a Molecular Biology |0 (DNLM)D008967 | |
| 650 | 6 | |a G�en�etique m�edicale. |0 (CaQQLa)201-0001432 | |
| 650 | 6 | |a G�en�etique mol�eculaire humaine. |0 (CaQQLa)201-0231342 | |
| 650 | 7 | |a HEALTH & FITNESS |x Diseases |x General. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Clinical Medicine. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Diseases. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Evidence-Based Medicine. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Internal Medicine. |2 bisacsh | |
| 650 | 7 | |a Human molecular genetics |2 fast |0 (OCoLC)fst00963180 | |
| 650 | 7 | |a Medical genetics |2 fast |0 (OCoLC)fst01014133 | |
| 700 | 1 | |a Friedmann, Theodore, |d 1935- |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Molecular genetic medicine. Vol. 3 |z 0124620035 |w (OCoLC)33893946 |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780124620032 |z Texto completo |