Cargando…
Current topics in cellular regulation. Volume 31 /
Current Topics in Cellular Regulation.
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego, California :
Academic Press,
[1990]
|
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Current Topics in Cellular Regulation; Copyright Page; Table of Contents; Chapter1. Calcium as Intracellular Messenger: From Simplicity to Complexity; I. Introduction; II. The Simplicity of Ca2+ as Messenger; III. Ca2+ and Cyclic AMP as Synarchic Messengers; IV. Ca2+ Metabolism and Calcium Homeostasis during Sustained Cellular Responses; V. Ca2+ as Messenger in Sustained Cellular Responses; VI. Time-Dependent Changes in Cell Responsiveness; VII. The Complexity and Elegance of Ca2+ Messenger Generation, Readout, and Action; REFERENCES.
- Chapter 2. The Integration of Receptor-Regulated Intracellular Calcium Release and Calcium Entry across the Plasma MembraneI. Introduction; II. Sources of Activator Calcium; III. Mechanisms of Intracellular Calcium Release; IV. Mechanisms of Calcium Entry; V. Conclusions; REFERENCES; Chapter 3. The Role of Calcium in Neurotransmitter Release: Existing Models and New Approaches to Evaluate Possible Mechanisms; I. Introduction; II. Current Models of the Mechanism of Synaptic Release; III. Experimental Models and Techniques Applied to the Study of Secretion.
- IV. Role of Second Messengers in ExocytosisV. Concluding Remarks; REFERENCES; Chapter 4. Regulation of Free Calmodulin Levels in Neurons by Neuromodulin: Relationship to Neuronal Growth and Regeneration; I. Discovery of Neuromodulin as a Calmodulin-Binding Protein; II. Distribution of Neuromodulin within Brain; III. Physical Properties of Neuromodulin; IV. Primary Amino Acid Sequence of Neuromodulin and Identification of Its Calmodulin-Binding Domain; V. Regulation of Calmodulin Binding to Neuromodulin by Protein Kinase C Phosphorylation and Calcineurin Dephosphorylation.
- VI. Cloning of cDNAs Encoding Neuromodulin and Expression of the Protein in Escherichia coliVII. Recognition of the Homology between Neuromodulin and GAP-43; Physiological Functions of the Protein; VIII. Biochemical Model for Regulation of Neurite Extension by Neuromodulin; REFERENCES; Chapter 5. Calcium/Calmodulin-Dependent Protein Kinase II; I. Introduction; II. The CaM Kinase II Isozyme Family; III. Substrate Consensus Phosphorylation Sequence; IV. Regulatory Properties of CaM Kinase II; V. Identification of Regulatory Domains of CaM Kinase II; VI. Physiological Role of CaM Kinase II.
- VII. SummaryREFERENCES; Chapter 6. The Molecular Structure and Regulation of Muscular Calcium Channels; I. Introduction; II. Composition of the Skeletal Muscle CaCB Receptor/ Calcium Channel; III. Primary Sequence of the Channel Subunits; IV. Binding Characteristics of the Purified Channel; V. Reconstitution of the Calcium Channel Receptor Complex and Its Physiological Function; VI. Structure of Nonskeletal Muscle L-Type Calcium Channels; VII. In Vivo Regulation and Conclusion; REFERENCES; Chapter 7. Na+-Ca2+ Exchanger: The Elusive Protein; I. Introduction.