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040 |a OPELS  |b eng  |e rda  |e pn  |c OPELS  |d N$T  |d YDXCP  |d EBLCP  |d DEBSZ  |d OCLCO  |d OCLCQ  |d OCLCO  |d UAB  |d MERUC  |d OCLCQ  |d OCLCO  |d OCLCA  |d OCLCQ  |d OCLCO  |d OCLCQ  |d OCLCO  |d OCLCQ  |d OCL  |d OCLCO 
019 |a 897643303  |a 907115540 
020 |a 9781483218007  |q (electronic bk.) 
020 |a 1483218007  |q (electronic bk.) 
020 |z 0123042070 
020 |z 9780123042071 
035 |a (OCoLC)893872985  |z (OCoLC)897643303  |z (OCoLC)907115540 
050 4 |a QP552.P4  |b P47 1985eb 
060 4 |a W1  |b PE769W v.7 1985 
060 4 |a QU 68  |b C748 1985 
072 7 |a SCI  |x 008000  |2 bisacsh 
082 0 4 |a 574.196  |2 22 
245 0 0 |a Conformation in biology and drug design /  |c edited by Victor J. Hruby. 
264 1 |a Orlando :  |b Academic Press,  |c 1985. 
300 |a 1 online resource (xix, 495 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a The Peptides ;  |v volume 7 
504 |a Includes bibliographical references and index. 
588 0 |a Print version record. 
505 0 |a Front Cover; Conformation in Biology and DrugDesign; Copyright Page; Table of Contents; Contributors; Preface; Nomenclature and Abbreviations; Chapter 1. A Perspective on the Application of Physical Methods to Peptide Conformational-Biological Activity Studies; I. Introduction; II. Some Biological Considerations; III. Historical Development of Peptide Conformational Studies in Solution; IV. Theoretical Methods for Examining Peptide Conformations; V. Application of Conformational and Dynamic Studies of Peptides to Their Biological Activities; Acknowledgment; References. 
505 8 |a Chapter 2. Circular Dichroism of PeptidesI. Introduction; II. General Aspects of Peptide CD; III. Specific Systems; Acknowledgments; References; Chapter 3. Application of Fluorescence Techniques in Studies of Peptide Conformations and Interactions; I. Introductory Remarks; II. Fluorophores in Peptides; III. Fluorescence Quantum Yield and Lifetime Measurements; IV. Fluorescence Polarization Studies; V. Measurement of Intramolecular Distances by Singlet-Singlet Resonance Energy Transfer Experiments; VI. Fluorescence Studies of Peptide Interactions with Macromolecular Systems; VII. Concluding Remarks. 
505 8 |a AcknowledgmentReferences; Chapter 4. Theoretical Methods in the Analysis of Peptide Conformation; I. Introduction; II. Definitions and Conventions; III. Methodology; IV. Results; References; Chapter 5. Theoretical Simulation of Conformation, Energetics, and Dynamics of Peptides; I. Introduction; II. Techniques and Methodology; III. Applications; IV. Summary and Future Directions; Acknowledgments; References; Chapter 6. Paramagnetic Metal Ions as Nuclear Magnetic Resonance Probes of Peptide Conformation in Solution; I. Introduction; II. Paramagnetic Metal Ion-Induced Shifts and Relaxation Enhancements. 
505 8 |a III. ConclusionsReferences; Chapter 7. Nuclear Magnetic Resonance Studies of Peptide-Macromolecule Interactions; I. Introduction; II. Nuclear Magnetic Resonance Techniques; III. Peptide-Protein Interaction; IV. Peptide-Lipid Interaction; V. Peptide-Nucleic Acid Interactions; VI. Conclusions and Prospects; References; Chapter 8. Solid-State Nuclear Magnetic Resonance of Peptides; I. Introduction; II. Methods; III. Applications; IV. Prospects; Acknowledgments; References; Chapter 9. Modern Nuclear Magnetic Resonance Spectroscopy of Peptides; I. Introduction; II. Conformational Homogeneity. 
505 8 |a III. General Strategy for Nuclear Magnetic Resonance Investigation of PeptidesIV. Assignment of Proton Nuclear Magnetic Resonance Signals; V. Heteronuclear Techniques; VI. Sequence Analysis; VII. Quantitative Evaluation of Nuclear Magnetic Resonance Spectra; VIII. Conclusions; Acknowledgments; References; Index. 
520 |a Conformation in Biology and Drug Design. 
650 0 |a Peptides  |x Analysis. 
650 0 |a Drugs  |x Structure-activity relationships. 
650 0 |a Conformational analysis. 
650 0 |a Structure-activity relationships (Biochemistry) 
650 0 |a Peptides. 
650 2 |a Peptides  |x analysis  |0 (DNLM)D010455Q000032 
650 2 |a Structure-Activity Relationship  |0 (DNLM)D013329 
650 2 |a Peptides  |0 (DNLM)D010455 
650 6 |a Peptides.  |0 (CaQQLa)201-0006528 
650 6 |a Peptides  |0 (CaQQLa)201-0006528  |x Analyse.  |0 (CaQQLa)201-0374819 
650 6 |a M�edicaments  |x Relations structure-activit�e.  |0 (CaQQLa)201-0028672 
650 6 |a Analyse conformationnelle.  |0 (CaQQLa)201-0002575 
650 6 |a Relations structure-activit�e (Biochimie)  |0 (CaQQLa)201-0028673 
650 7 |a SCIENCE  |x Life Sciences  |x Biology.  |2 bisacsh 
650 7 |a Structure-activity relationships (Biochemistry)  |2 fast  |0 (OCoLC)fst01135737 
650 7 |a Peptides  |2 fast  |0 (OCoLC)fst01057564 
650 7 |a Conformational analysis  |2 fast  |0 (OCoLC)fst00875033 
650 7 |a Drugs  |x Structure-activity relationships  |2 fast  |0 (OCoLC)fst00898929 
650 7 |a Peptides  |x Analysis  |2 fast  |0 (OCoLC)fst01057565 
650 7 |a Peptide  |2 gnd  |0 (DE-588)4045125-2 
650 7 |a Struktur-Aktivit�ats-Beziehung  |2 gnd  |0 (DE-588)4183784-8 
650 7 |a Aufsatzsammlung  |2 gnd  |0 (DE-588)4143413-4 
700 1 |a Hruby, Victor J.,  |d 1938- 
776 0 8 |i Print version:  |t Conformation in biology and drug design  |z 0123042070  |w (DLC) 78031958  |w (OCoLC)17918575 
830 0 |a Peptides (Academic Press) ;  |v v. 7. 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780123042071  |z Texto completo