The receptors. Volume II /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Conn, P. Michael (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Orlando : Academic Press, Inc. (Harcourt Brace Jovanovich, Publishers, 1985.
Temas:
Cell receptors.
Drug receptors.
Binding sites (Biochemistry)
Receptors, Cell Surface
Receptors, Drug
Binding Sites
R�ecepteurs cellulaires.
R�ecepteurs de m�edicaments.
Sites actifs (Biochimie)
MEDICAL > Pharmacology.
Drug receptors
Cell receptors
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; The Receptors; Copyright Page; Table of Contents; Contributors; Preface; Contents of Previous Volume; CHAPTER 1. The Vitamin D Receptor; I. Introduction; II. Discovery of the Receptor Proteins for 1,25-(OH)2D3; III. Biochemical and Physical Properties of the 1,25-(OH)2D3 Receptor; IV. Mechanism of Action of the 1,25-(OH)2D3 Receptor; V. Regulation of Receptor Number; VI. Purification of Chick Intestinal 1,25-(OH)2D3 Receptor; VII. Antibodies to Chick Intestinal 1,25-(OH)2D3 Receptor; VIII. Conclusions; References
  • CHAPTER 2. On Experimental Discrimination between Alternative Mechanistic Models for the Receptor-Mediated Stimulation of Adenylate CyclaseI. Introduction; II. General Assumptions, Definitions, and Nomenclature; III. Is the Receptor a Catalyst or a Reactant?; IV. What Are the Functional Relationships between R, N, and C, and How Are They Affected by Agonist and Guanine Nucleotide?; V. Summary; References; CHAPTER 3. The Role of Microaggregation in Hormone-Receptor-Effector Interactions; I. Introduction; II. The GnRH Receptor
  • III. Evidence That Microaggregation Plays a Key Role in Other Antibody-Receptor-Effector SystemsIV. The Adenylate Cyclase System; V. Receptor-Effector Interactions Revisited; References; CHAPTER 4. The Ah Receptor: A Biochemical and Biologic Perspective; I. Introduction; II. Biochemical Characterization of the Ah Receptor; III. Biology of the Ah Receptor; IV. Mechanism(s) of Action: Cell Biology and Biochemical Approaches; V. Concluding Comments; References; CHAPTER 5. Interactions of Animal Viruses with Cell Surface Receptors; I. Introduction; II. Viral Attachment Proteins
  • III. Identification of Cell Surface ReceptorsIV. Cell Surface Receptor Determinants of Animal Viruses; V. Role of Receptors in Viral Penetration; VI. Role of Viral Receptors in Host Range and Tissue Tropism; VII. Summary and Future Perspectives; References; CHAPTER 6. Studies on Insulin Receptors: Implications for Insulin Action; I. Introduction; II. Receptor Purification; III. Receptor Structure; IV. Glycoprotein Nature of the Insulin Receptor; V. Tyrosyl Phosphorylation; VI. Interrelations of the Insulin Receptor to Other Receptor Structures
  • VII. Receptor-Mediated Internalization and Degradation of InsulinVIII. Down-Regulation; IX. Possible Involvement of Cytoskeletal Elements in Insulin Action; X. Receptor Valence; XI. Nonlinear Scatchard Plots; XII. Possible Role for Receptor Cross-Linking and for Non-Insulin-Binding Regulatory Glycoprotein; XIII. Transmembrane Signaling; References; CHAPTER 7. Size of Neurotransmitter Receptors as Determined by Radiation Inactivation-Target Size Analysis; I. Introduction; II. Radiation Inactivation-Target Size Analysis; III. Conclusions and Avenues for Further Study; References

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