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Epigenetics /
This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume concentrates on Epigenetics This book looks at Epigeneticsin the light of the newest scholarly discoveries and insights.
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Waltham, Massachusetts :
Elsevier,
2014.
|
| Edición: | First edition. |
| Colección: | International review of neurobiology ;
v. 115. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
MARC
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| 245 | 0 | 0 | |a Epigenetics / |c edited by Subhash C. Pandey. |
| 250 | |a First edition. | ||
| 264 | 1 | |a Waltham, Massachusetts : |b Elsevier, |c 2014. | |
| 264 | 4 | |c �2014 | |
| 300 | |a 1 online resource (347 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a International Review of Neurobiology, |x 0074-7742 ; |v Volume 115 | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Online resource; title from PDF title page (ebrary, viewed August 27, 2014). | |
| 505 | 0 | |a Front Cover; Epigenetics; Copyright; Contents; Contributors; Preface; Chapter One: Environmental Alterations of Epigenetics Prior to the Birth; 1. Introduction; 2. Manifestation of Environmental Factors; 2.1. Substances of abuse; 2.1.1. Drinking; 2.1.2. Smoking; 2.1.3. Cocaine; 2.1.4. Cannabis; 2.1.5. Opioid; 2.1.6. Methamphetamine; 2.2. Diet and nutrition; 2.2.1. Folic acid; 2.2.2. Caffeine; 2.3. Prescriptive medicine; 2.3.1. Valproic acid; 2.3.2. �-Hydroxybutyrate; 2.4. Environmental toxins and pollutants; 2.4.1. Arsenic; 2.4.2. Lead; 2.4.3. Cadmium; 2.4.4. Methyl mercury. | |
| 505 | 8 | |a 2.4.5. Bisphenol A2.5. Stress and aversive life experience; 3. Mechanisms of Environmentally Induced Epigenetic Changes; 3.1. On DNA methylation; 3.2. On histone modification; 3.3. On miRNA and other noncoding RNA; 3.4. On transposable elements; 4. Effect of Epigenetic Alterations on Neurodevelopment; 4.1. Epigenetic functional concerns; 4.2. Intrinsic epigenetic program; 4.3. Alcohol drinking, epigenetics phenotypes, and FASDs; 4.3.1. Effect on germline and placenta; 4.3.2. Effect on embryonic and early brain development; 4.3.3. Potential late-onset effect; 4.3.4. Transgenerational effect. | |
| 505 | 8 | |a AcknowledgmentsReferences; Chapter Two: Transgenerational Epigenetics and Brain Disorders; 1. Introduction to Transgenerational Epigenetic Inheritance; 2. Epigenetics and Epigenetic Processes; 3. Evidence for Transgenerational Epigenetic Inheritance; 4. Germline-Independent Epigenetic Inheritance; 5. Germline-Dependent Epigenetic Transmission; 6. Transgenerational Epigenetic Effects on Brain Disorders; 7. Concluding Remarks; Acknowledgment; References; Chapter Three: The Epigenetic Landscape of Alcoholism; 1. Introduction; 2. Epigenetic Regulation due to Histone Covalent Modifications. | |
| 505 | 8 | |a 2.1. Role of histone acetylation and deacetylation in transcriptional regulation2.2. Alcohol and histone acetylation and deacetylation mechanisms in the brain; 2.3. Role of HDACs in alcoholism; 2.4. Alcohol and histone acetylation and deacetylation mechanisms in nonneuronal tissues; 2.5. Other drugs of abuse and histone acetylation and deacetylation mechanisms; 2.6. Alcohol and histone methylation mechanisms; 2.7. Alcohol and histone phosphorylation mechanisms; 3. Epigenetic Regulation due to DNA Methylation; 3.1. Functions of DNMTs and MBDs; 3.2. DNA demethylation pathways in the brain. | |
| 505 | 8 | |a 3.3. Alcohol and DNA methylation and demethylation mechanisms3.4. Alcohol and DNA methylation mechanisms in nonneuronal tissues; 3.5. Other drugs of abuse and DNA methylation mechanisms; 3.6. DNMT inhibitors as a therapy for drug addiction; 3.7. Epigenetics of adolescent drinking and implications for alcohol phenotypes in later life; 3.8. Epigenetic regulation of glial-neuronal interactions and alcohol; 4. Genome-Wide Approaches to Understand the Basis of Alcoholism; 5. Using Invertebrate Models to Study the Basis of Ethanol Phenotypes; 6. Inheritance of a Drug Phenotype; 7. Conclusions. | |
| 520 | |a This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume concentrates on Epigenetics This book looks at Epigeneticsin the light of the newest scholarly discoveries and insights. | ||
| 650 | 0 | |a Epigenesis. | |
| 650 | 0 | |a Epigenetics. | |
| 650 | 6 | |a �Epig�en�ese. |0 (CaQQLa)201-0066257 | |
| 650 | 6 | |a �Epig�en�etique. |0 (CaQQLa)000270630 | |
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| 650 | 7 | |a MEDICAL |x Clinical Medicine. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Diseases. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Evidence-Based Medicine. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Internal Medicine. |2 bisacsh | |
| 650 | 7 | |a Epigenesis |2 fast |0 (OCoLC)fst00914128 | |
| 650 | 7 | |a Epigenetics |2 fast |0 (OCoLC)fst01893642 | |
| 700 | 1 | |a Pandey, Subhash C., |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Epigenetics. |b First edition. |d Waltham, Massachusetts : Elsevier, �2014 |h xiii, 329 pages |k International review of neurobiology ; Volume 115 |x 0074-7742 |z 9780128013113 |
| 830 | 0 | |a International review of neurobiology ; |v v. 115. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780128013113 |z Texto completo |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/bookseries/00747742/115 |z Texto completo |