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Methods in neurosciences /
Neuropeptide Analogs, Conjugates, and Fragments.
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego, California :
Academic Press,
[1993]
|
| Colección: | Methods in neurosciences ;
v. 13. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Cover image; Title page; Table of Contents; Copyright page; Contributors to Volume 13; Preface; Methods in Neurosciences; Chapter 1: Synthetic Approaches to Incorporation of Novel Amino Acids into Gonadotropin-Releasing Hormone Peptides; Publisher Summary; Introduction; [NMeTyr5,DLeu6,Pro9NHEt]GnRH; Synthesis of [NMeTyr5,DLeu6,Pro9NHEt]GnRH (1); Purification and Characterization of [NMeTyr5,DLeu6,Pro9NHEt]GnRH (1); Synthesis, Purification, and Characterization of [NMeSer4,DLeu6,Pro9NHEt]GnRH (2); Synthesis, Purification, and Characterization of [NMeSer4,D2Nal6]GnRH (3)
- Synthesis, Purification, and Characterization of [N-(3-Indolylpropionyl)Ser4,DLys(Isp)6,Pro9NHEt]GnRH(4-9) (8)Comments about Syntheses of Hexapeptide Reduced Size GnRH Analogs; Appendix: Equipment, Materials, and Methods; Acknowledgments; Chapter 2: Synthesis of Pseudopeptides; Publisher Summary; Introduction; Synthesis of Pseudodipeptide Units; Incorporation of tert-Butyloxycarbonyl-Protected Pseudodipeptides within Peptide Analogs; Experimental; Characterization of Pseudopeptides by Chemical and Physical Methods; Acknowledgments
- Chapter 3: Synthesis and Synthetic Manipulations of Peptides Derived from Parathyroid Hormone and Parathyroid Hormone-Related ProteinPublisher Summary; Introduction; Chemical Synthesis; Synthesis of Parathyroid Hormone-Related Protein Peptides; Synthesis of Substituted Analogs of Parathyroid Hormone and Parathyroid Hormone-Related Protein; Synthesis of Radioligands; Parathyroid Hormone Analogs: Affinity and Photoaffinity Ligands; Recombinant DNA Techniques; Random Mutagenesis of Parathyroid Hormone Sequence; Conclusions
- Chapter 4: Biotinylated Neuropeptide Analogs: Design and Use as Probes for Target Cells in Heterogeneous PopulationsPublisher Summary; Introduction; Biotin-Avidin Complex; Peptide Analogs Designed for Biotinylation; Design Strategies; Addition of Biotin to Designer Peptide; Separation of Biotinylated Products; Chemical Characterization of Biotinylated Peptides; Examples; Peptide Design and Biotinylation; Use of Biotinylated Peptides as Probes for Target Cells; Conclusion; Acknowledgments; Chapter 5: Peptide Characterization and Purification Using High-Performance Liquid Chromatography