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Proteomics in Biomedicine and Pharmacology /

Volume 95 of Advances in Protein Chemistry and Structural Biology focuses on advances in proteomic techniques and their application in biomedicine and pharmacology. This volume describes in detail the applications of these techniques in studying a number of diseases and specific protein modification...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Donev, Rossen (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Waltham, Massachusetts : Academic Press, 2014.
Edición:First edition.
Colección:Advances in protein chemistry and structural biology ; v. 95.
Temas:
Acceso en línea:Texto completo
Texto completo

MARC

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245 0 0 |a Proteomics in Biomedicine and Pharmacology /  |c edited by Rossen Donev. 
250 |a First edition. 
264 1 |a Waltham, Massachusetts :  |b Academic Press,  |c 2014. 
264 4 |c �2014 
300 |a 1 online resource (377 pages) :  |b illustrations 
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490 1 |a Advances in Protein Chemistry and Structural Biology,  |x 1876-1623 ;  |v Volume 95 
546 |a Text in English. 
504 |a Includes bibliographical references and indexes. 
588 0 |a Online resource; title from PDF title page (ebrary, viewed July 23, 2014). 
505 0 |a Front Cover; Proteomics in Biomedicine and Pharmacology; Copyright; Contents; Contributors; Preface; Chapter One: Application of Cutting-Edge Proteomics Technologies for Elucidating Host-Bacteria Interactions; 1. Introduction; 2. Classical Proteomics Strategies for Biomedical Research in General; 2.1. Gel-based methods; 3. Gel-Free Methods; 3.1. Gel-free-labeling methods; 3.1.1. Chemical labeling; 3.1.2. Metabolic labeling; 3.2. Label-free and absolute quantification; 4. New Proteomic Methods in Looking for Bacterial Pathogens; 5. Proteomic Advances in Looking for Host Organisms; 6. Prospects. 
505 8 |a 3. Applications of Phosphoproteomics in Biomedicine3.1. Applications in cancer research; 3.2. Applications in stem cell research; 3.3. Applications in cardiac research; 3.4. Applications in immunity research; 4. Discussion; References; Chapter Three: Recent Advances in Mass Spectrometry-Based Glycoproteomics; 1. Introduction; 2. Glycoproteomic Profiling by MS; 2.1. Glycoproteomics methodology; 2.2. Affinity enrichment; 2.3. Glycoprotein digestion; 2.4. Glycan release; 2.5. Chromatographic separation and SPE; 2.6. Mass spectrometry; 2.7. Quantitation; 2.8. Bioinformatics. 
505 8 |a 3. MS-Based Glycoproteomics in Disease Research3.1. Cancer biomarker research; 3.2. Neurodegenerative disease research; 4. Concluding Remarks; Acknowledgments; References; Chapter Four: Proteomics and Proteogenomics Approaches for Oral Diseases; 1. Introduction; 2. An Integrated Proteogenomics Protocol for Personalized Dentistry; 2.1. Human samples; 2.1.1. Tissues; 2.1.2. Blood; 2.1.3. Dental plaque and oral biofilms; 2.1.4. Gingival crevicular fluid; 2.1.5. Saliva; 2.1.6. Oral rinse; 2.2. Bioinformatics analysis; 2.2.1. Bioinformatics resources; 2.2.2. Leader-gene algorithm. 
505 8 |a 2.3. Proteomics technologies, with a focus on the label-free tools2.3.1. Mass spectrometry; 2.3.2. Anodic porous alumina; 2.3.3. Nucleic acid programmable protein arrays; 3. Oral Diseases; 3.1. Dental caries; 3.2. Periodontitis; 3.3. Oral lichen planus; 3.4. Oral cancer; 4. Concluding Remarks; References; Chapter Five: Advances in Nanocrystallography as a Proteomic Tool; 1. Introduction; 2. Langmuir-Blodgett (LB)-Based Crystallization; 3. Comparison of LB-Based Crystallization with Other Techniques; 4. Fourier Transform Infrared (FTIR) Spectroscopy for Investigating LB-Films. 
520 |a Volume 95 of Advances in Protein Chemistry and Structural Biology focuses on advances in proteomic techniques and their application in biomedicine and pharmacology. This volume describes in detail the applications of these techniques in studying a number of diseases and specific protein modifications and profiles, including phosphoproteomics, glycoproteomics, and more. Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series is the essential resource for protein chemists. Each volume brings forth new information about protocols. 
650 0 |a Proteomics. 
650 0 |a Pharmacology. 
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650 6 |a Prot�eomique.  |0 (CaQQLa)201-0363192 
650 6 |a Pharmacologie.  |0 (CaQQLa)201-0007219 
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650 7 |a Proteomics.  |2 fast  |0 (OCoLC)fst01079785 
700 1 |a Donev, Rossen,  |e editor. 
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