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Advances in drug research. Volume 22 /
Advances in Drug Research, Volume 22 focuses on the concepts and facts of drug research. This book is divided into four chapters. Chapter 1 discusses the use of atomic properties and atom-centered indices in QSAR models, while Chapter 2 describes the pharmacokinetics of peptides and proteins. The nu...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
[Place of publication not identified] :
Academic Press,
1992.
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| Colección: | Advances in drug research ;
vol. 22. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
Tabla de Contenidos:
- Front Cover; Advances in Drug Research; Copyright Page; Table of Contents; CONTRIBUTORS; PREFACE: All mimsy were the borogoves
- Chapter 1. Atom Description in QSAR Models: Development and Use of an Atom Level Index; 1 Introduction; 2 An Atom Level Description of Structure; 3 Formulation of an Atom-Centred Index; 4 Information from Electrotopological State Values; 5 QSAR Strategy; 6 Applications to Drug QSAR Problems; 7 Discussion; References; Chapter 2. Pharmacokinetics of Peptides and Proteins: Opportunities and Challenges; 1 Introduction.
- 2 Physicochemical Factors and Passive Distribution3 Clearance; 4 Transport of Peptides Across Mucosal Surfaces; 5 Conclusions; References; Chapter 3. Towards Genomic Pharmacology: From Membranal to Nuclear Receptors; 1 Introduction; 2 Regulation of Gene Expression; 3 Nuclear Receptors; 4 Induced Changes in Gene Expression; 5 The Nucleus as a Target for Drug Action; 6 Signal Pathways: From Membrane to Nuclear Receptors; 7 Future Prospects; Acknowledgements; References; Chapter 4. Medicinal Chemistry of Steroids: Recent Developments; 1 Introduction; 2 Steroid Receptors.