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Advances in drug research. Volume 18 /
Each volume in this distinguished series presents authoritative reviews, both generally, on topics of broad interest in drug research, and specifically, on novel and established therapeutic classes. Acknowledged experts contribute in areas such as drug design, clinical and molecular pharmacology, dr...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London :
Academic Press,
1989.
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| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
MARC
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| 245 | 0 | 0 | |a Advances in drug research. |n Volume 18 / |c volume edited by Bernard Testa. |
| 264 | 1 | |a London : |b Academic Press, |c 1989. | |
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 500 | |a Includes indexes. | ||
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a Front Cover; Advances in Drug Research; Copyright Page; Table of Contents; CONTRIBUTORS; PREFACE: AT THE FUNFAIR?; References; Chapter 1. Molecular Mechanisms of Specificity in DNA-Antitumour Drug Interactions; 1 Introduction: The Main Modes of Binding of Antitumour Drugs to DNA; 2 Factors Governing the Specificity of Interaction of Non-intercalating Groove-binding Antitumour Drugs with DNA; 3 Factors Governing the Specificity of Interaction of Intercalating Antitumour Drugs with DNA; 4 Factors Involved in the Sequence-selective Interaction of Covalently Bound Antitumour Drugs with DNA. | |
| 505 | 8 | |a 5 Concluding RemarksAcknowledgement; References; Chapter 2. The Structure and Receptor Binding of Steroid Hormones; 1 Introduction; 2 Steroid Structure and Receptor Binding; 3 Steroid Hormone Antagonists; 4 Steroid Receptor Structures; 5 Summary; Acknowledgements; References; Chapter 3. Aldose Reductase Inhibitors: Structure-Activity Relationships and Therapeutic Potential; 1 Introduction; 2 Structure-Activity Relationships of Aldose Reductase Inhibitors; 3 Therapeutic Potential of Aldose Reductase Inhibitors; 4 Conclusion; References. | |
| 505 | 8 | |a Chapter 4. Opioid Receptors and their Ligands: Recent Developments1 Introduction; 2 Novel Opiates; 3 Opioid Peptides; 4 Affinity Labelling; 5 Receptor Subtype Investigations; 6 Opioid Receptors: Facts and Scenarios; 7 Concluding Remarks; References; Chapter 5. Purine Receptors and their Pharmacological Roles; 1 Introduction; 2 Purine Receptors; 3 Physiological Roles and Pharmacological Activity; 4 Concluding Remarks; References; Chapter 6. Muscarinic Cholinergic Receptors and their Interactions with Drugs; 1 Introduction; 2 Receptor Characterization by Means of Binding Studies. | |
| 505 | 8 | |a 3 Binding of Radiolabelled Ligands to Muscarinic Receptors4 Allosteric and Cooperative Interactions of Muscarinic Receptors; 5 Binding of Agonists; 6 Localization of Muscarinic Receptors; 7 Subtypes of Muscarinic Receptors; 8 Regulation of Muscarinic Receptors and their Interaction with Other Membrane Proteins; 9 The Membrane Matrix and Lateral Mobility; 10 Purification of the Muscarinic Receptor; 11 Molecular Properties of Muscarinic Receptors; 12 From Ontogeny to Ageing; 13 Concluding Remarks; Acknowledgements; References; SUBJECT INDEX; CUMULATIVE INDEX OF AUTHORS. | |
| 520 | |a Each volume in this distinguished series presents authoritative reviews, both generally, on topics of broad interest in drug research, and specifically, on novel and established therapeutic classes. Acknowledged experts contribute in areas such as drug design, clinical and molecular pharmacology, drug metabolism, and mechanisms of action. Reviewers have consistently praised Advances in Drug Research for its comprehensive and lucid summaries of up-to-date knowledge. | ||
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| 700 | 1 | |a Testa, Bernard. | |
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| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/bookseries/00652490/18 |z Texto completo |