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Advances in drug delivery systems, 6 : proceedings of the Sixth International Symposium on Recent Advances in Drug Delivery Systems, Salt Lake City, UT, U.S.A., February 21-24, 1993 /
Advances in Drug Delivery Systems, 6.
| Clasificación: | Libro Electrónico |
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| Autor Corporativo: | |
| Otros Autores: | |
| Formato: | Electrónico Congresos, conferencias eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam ; London :
Elsevier,
1994.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Advances in Drug Delivery Systems, 6; Copyright Page; Preface; Table of Contents; Part I: Novel Drug Delivery Systems; Chapter 1. Biologically engineered microstructures: controlled release applications; Introduction; Microstructure geometry and controlled release; Flat porus media; Spheres; Rigid hollow microcylinders; Controlled release from microcylinders; Antifouling applications; Methods for environmental exposure testing; Controlled release of proteins from lipid microcylinders; Summary and Conclusion; Acknowledgements; References.
- Chapter 2. New approaches to targeting bioactive compoundsIntroduction; Fatty acylated antibodies; Effect of artificial fatty acylation on protein binding and uptake; Suppression of virus reproduction with fatty acylated antiviral antibodies; Therapeutic efficiency of fatty acylated antiviral antibodies; Antisense oligonucleotides combined with a lipid moiety; DNA interpolyelectrolyte complexes as a tool for gene delivery into a cell; Respecrins: a new class of immunotoxins; Acknowledgments; References; Chapter 3. Mucosal delivery of macromolecules; Introduction; Experimental; Materials.
- Buccal solution preparationBuccal device fabrication; In vivo experiments; Intravenous bolus experiments; Buccal solution experiments; Buccal device experiments; Results and Discussion; Conclusions; References; Chapter 4. Targeted delivery of diagnostic agents by surface-modified liposomes; Introduction; The mechanism of protective action of PEG on liposomes; Co-immobilization of PEG and antibody on the liposome surface: long-circulating immunoliposome accumulation in myocardial infarct.
- Surface modification of liposomes with chelating groups for delivery of imaging agents: lymph node visualization and modification of MRI contrast properties of Gd-liposomesAcknowledgement; References; Chapter 5. Influencing factors on in vitro micelle stability of adriamycin-block copolymer conjugates; Introduction; Experimental part; Materials; Preparation of drug-block copolymer conjugates; HPLC measurements; Results and Discussion; Conclusions; Acknowledgements; References; Chapter 6. SK & F 110679: comparison of absorption following oral or respiratory administration; Introduction.
- Materials and MethodsChemicals; Intestinal transport of SK & F 110679; Intraduodenal administration of SK & F 110679; Intratracheal dosing and measurement of plasma growth hormone levels in rats; Intratracheal and intravenous dosing of SK & F 110679 in dogs; Measurement of plasma levels of SK & F 110679; Data analysis; Transport of [3H]SK & F 110679 across rabbit intestinal mucosa in vitro; Absorption of SK & F 110679 in the rat; Plasma concentrations of SK & F 110679 following intravenous, intraduodenal or intratracheal administration in dogs; Discussion; Acknowledgements; References.