Drug design. Volume III /
Drug Design, Volume III covers the mode of action of biologically active compounds. The book discusses microbial transformations that have been used in the preparation of drugs or closely related substances; the use of linear free energy parameters and other experimental constants in structure-activ...
Clasificación: | Libro Electrónico |
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Otros Autores: | |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
New York :
Academic Press,
1972.
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Colección: | Medicinal chemistry (Academic Press) ;
v. 11. |
Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Drug Design; Copyright Page; Table of Contents; List of Contributors; Preface; Contents of Other Volumes; Chapter 1. Microbial Conversion as a Tool in the Preparationof Drugs; I. Introduction; II. Practical Aspects of Microbial Transformations; III. Some Theoretical Aspects of Microbial Transformations; IV. Conversions by Microorganisms; ACKNOWLEDGMENTS; REFERENCES; Chapter 2. The Use of Linear Free Energy Parameters and Other Experimental Constants in Structure-Activity Studies; I. Introduction; II. Parameters Used in Structure-Activity Studies.
- Chapter 6. The Design of Local AnestheticsI. Introduction; II. General Considerations on the Development of New Drugs; III. The Classical Procedures for the Development of Local Anesthetics; IV. Rational Methods for the Development of Local Anesthetics; References; Chapter 7. Design of Insect Chemosterilants; I. Introduction; II. Desirable Characteristics of Chemosterilants; III. Methods of Evaluating Chemosterilants; IV. Mechanism of Action; V. Some Unexplored Areas of Research; REFERENCES; Chapter 8. Molecular Approach for Designing Inhibitors to Enzymes Involved in Blood Clotting.
- I. Background InformationII. Thrombin; III. Fibrinoligase; IV. Conclusion; REFERENCES; Author Index; Subject Index.