Drug design. Volume II /

Drug Design, Volume II covers the design of bioactive compounds interacting with enzymes and playing a role in enzyme synthesis. The book discusses the modulation of pharmacokinetics by molecular manipulation; the factors in the design of reversible and irreversible enzyme inhibitors; and the design...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Ari�ens, E. J. (Everhardus Jacobus) (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Academic Press, 1971.
Colección:Medicinal chemistry (Academic Press) ; v. 11.
Temas:
Pharmacology.
Pharmaceutical chemistry.
Drugs.
Research.
Chemistry, Pharmaceutical
Pharmaceutical Preparations
Research
Pharmacology
Pharmacologie > Collections.
Chimie pharmaceutique.
Pharmacologie.
M�edicaments.
Recherche.
pharmacology.
research (function)
MEDICAL > Pharmacology.
Drugs
Pharmaceutical chemistry
M�edicaments > Conception.
M�edicaments > Relations structure-activit�e.
M�edicaments > Pharmacocin�etique.
Acceso en línea:Texto completo
Descripción
Sumario:Drug Design, Volume II covers the design of bioactive compounds interacting with enzymes and playing a role in enzyme synthesis. The book discusses the modulation of pharmacokinetics by molecular manipulation; the factors in the design of reversible and irreversible enzyme inhibitors; and the design of organophosphate and carbamate inhibitors of cholinesterases. The text also describes the design of reactivators for irreversibly blocked acetylcholinesterase; drug design based on the inhibition of protein synthesis in the context of susceptible enzymic reactions; as well as the role of enzymes.
Descripción Física:1 online resource : illustrations
Bibliografía:Includes bibliographical references and indexes.
ISBN:9781483216041
1483216047

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