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Natural hosts of SIV : implication in AIDS /

Natural Hosts of SIV: Implications in AIDS thoroughly reviews the possible mechanisms by which African nonhuman primate natural hosts of lentiviruses remain essentially disease-free while other hosts exhibit disease and death. The book ultimately indicates directions for further research and potenti...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Ansari, Aftab A. (Aftab Ahmed) (Editor ), Silvestri, Guido (Professor of pathology and laboratory medicine) (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Academic Press is an imprint of Elsevier, [2014]
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Natural hosts of SIV :  |b implication in AIDS /  |c edited by Aftab A. Ansari, PhD, Professor, Department of Pathology & Laboratory Medicine, Emory University School of Medicine, Atlanta GA, USA [and] Guido Silvestri, Professor, Department of Pathology and Laboratory Medicine, Emory University School of Medicine & Yerkes National Primate Research Center Atlanta, GA, USA. 
264 1 |a London :  |b Academic Press is an imprint of Elsevier,  |c [2014] 
264 4 |c �2014 
300 |a 1 online resource (xvii, 385 pages) :  |b color illustrations, maps 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
500 |a Title from PDF version (EBSCO, viewed on July 17, 2014). 
520 |a Natural Hosts of SIV: Implications in AIDS thoroughly reviews the possible mechanisms by which African nonhuman primate natural hosts of lentiviruses remain essentially disease-free while other hosts exhibit disease and death. The book ultimately indicates directions for further research and potential translations of this compelling phenomenon into novel approaches to treat and prevent HIV. When Asian non-human primate non-natural hosts are experimentally infected with viruses isolated from African species, disease and death normally results. Meanwhile, these African nonhuman primate natural hosts maintain similar levels of plasma and cellular viremia and exhibit compellingly different, essentially disease-free, states. This work attempts to answer the question of how the natural host remains disease resistant. 
505 0 |a Front Cover; Natural Hosts Of SIV: Implication In AIDS; Copyright; Contents; Epigraphy; Contributors; Introduction; Chapter 1 -- Comparative Studies of Natural and Non-natural Hosts of SIV-An Overview; OVERVIEW; OUTLOOK; References; Chapter 2 -- History of Simian Immunodeficiency Virus Discovery; SERENDIPITOUS PATHWAYS TO AN AIDS MODEL AND SIV'S AFRICAN ORIGIN; SIVMAC EMERGED FROM THE CALIFORNIA NATIONAL PRIMATE RESEARCH CENTER MACAQUE COLONY; SURVIVORS OF THE MACAQUE LYMPHOMA OUTBREAK SENT TO THE NEW ENGLAND AND WASHINGTON PRIMATE RESEARCH CENTERS. 
505 8 |a WHAT'S IN A NAME? SIMIAN IMMUNODEFICIENCY VIRUS (AKA STLV-III, STLV-IIIAGM, AND HTLV-IV)ORIGINS OF SIVMAC FROM KURU EXPERIMENTS USING ASIAN RHESUS MONKEYS; BOB GORMUS AT THE TULANE NATIONAL PRIMATE RESEARCH CENTER UNCOVERS THE AFRICAN ORIGIN OF SIV; HIV-1 ANCESTRY DISCOVERED IN AN EX-PET CHIMPANZEE IN GABON; WAS SIVMAC THE IDEAL MODEL FOR AIDS?; ANCIENT ORIGINS OF THE SIV FAMILY IN AFRICA RAISE MORE QUESTIONS; References; Chapter 3 -- Simian Immunodeficiency Virus Infections in the Wild; INTRODUCTION; HISTORY; SIV CLASSIFICATION; EVOLUTION OF SIVS. 
505 8 |a HOW LONG WERE SIVS PRESENT IN NON-HUMAN PRIMATESCHALLENGES TO STUDY SIV INFECTION IN WILD NON-HUMAN PRIMATE POPULATIONS; SIV PREVALENCE AND MOLECULAR EPIDEMIOLOGY IN AFRICAN NON-HUMAN PRIMATES; TRANSMISSION OF SIMIAN RETROVIRUSES IN THEIR NATURAL HOSTS; HISTORY OF SIV IN THEIR NATURAL HOSTS; CONCLUSIONS; References; Chapter 4 -- Properties of Human and Simian Immunodeficiency Viruses; INTRODUCTION; COMMON FEATURES OF PRIMATE LENTIVIRUSES; UNIQUE FEATURES OF HIV-1 AND HIV-2 RELATED PRIMATE LENTIVIRUSES; PRIMATE LENTIVIRAL CORECEPTOR TROPISM AND PATHOGENESIS; CONCLUSIONS AND PERSPECTIVES. 
505 8 |a BACTERIAL, MYCOTIC, AND PARASITIC INFECTIONSVIRAL DISEASES; METABOLIC DISORDERS; AGING AND DEGENERATIVE DISORDERS; NEOPLASMS; MISCELLANEOUS DISORDERS; References; Chapter 7 -- Gastrointestinal Immunity in Natural Hosts of Simian Immunodeficiency Virus; INTRODUCTION; CD4 T-CELL DEPLETION OCCURS IN THE GI TRACT OF NATURAL AND NON-NATURAL HOSTS; INTERLEUKIN-17-PRODUCING CELLS ARE PREFERENTIALLY LOST IN THE GI TRACT DURING PATHOGENIC SIV INFECTION BUT ARE MAINTAINED IN NAT...; NATURAL HOSTS PRODUCE CD4 T CELLS THAT CAN PERFORM FUNCTIONS OF CD4+ T CELLS BUT ARE RESISTANT TO SIV INFECTION. 
546 |a English. 
650 0 |a Simian immunodeficiency virus. 
650 0 |a Natural immunity. 
650 0 |a HIV infections  |x Immunology. 
650 0 |a AIDS (Disease) 
650 1 2 |a Simian Immunodeficiency Virus  |x immunology  |0 (DNLM)D015302Q000276 
650 2 |a Immunity, Innate  |0 (DNLM)D007113 
650 2 |a Acquired Immunodeficiency Syndrome  |0 (DNLM)D000163 
650 2 2 |a Host-Pathogen Interactions  |x immunology  |0 (DNLM)D054884Q000276 
650 2 2 |a HIV  |x immunology  |0 (DNLM)D006678Q000276 
650 2 2 |a Simian Acquired Immunodeficiency Syndrome  |x immunology  |0 (DNLM)D016097Q000276 
650 2 2 |a HIV Infections  |x immunology  |0 (DNLM)D015658Q000276 
650 2 |a Simian Immunodeficiency Virus  |0 (DNLM)D015302 
650 6 |a Immunit�e naturelle.  |0 (CaQQLa)201-0055771 
650 6 |a Infections �a VIH  |0 (CaQQLa)201-0152700  |x Immunologie.  |0 (CaQQLa)201-0380076 
650 6 |a Sida.  |0 (CaQQLa)201-0119611 
650 6 |a Virus de l'immunod�eficience simienne.  |0 (CaQQLa)201-0352861 
650 7 |a Simian immunodeficiency virus (species)  |2 aat  |0 (CStmoGRI)aat300410427 
650 7 |a HEALTH & FITNESS  |x Diseases  |x General.  |2 bisacsh 
650 7 |a MEDICAL  |x Clinical Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Diseases.  |2 bisacsh 
650 7 |a MEDICAL  |x Evidence-Based Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Internal Medicine.  |2 bisacsh 
650 7 |a Natural immunity  |2 fast  |0 (OCoLC)fst01034361 
650 7 |a AIDS (Disease)  |2 fast  |0 (OCoLC)fst00793808 
650 7 |a Simian immunodeficiency virus  |2 fast  |0 (OCoLC)fst01763355 
655 4 |a Internet Resources. 
655 4 |a Maps. 
655 4 |a Plates. 
700 1 |a Ansari, Aftab A.  |q (Aftab Ahmed),  |e editor. 
700 1 |a Silvestri, Guido  |c (Professor of pathology and laboratory medicine),  |e editor. 
776 0 8 |i Print version:  |t Natural hosts of SIV.  |d Amsterdam : Elsevier : Academic Press, [2014]  |z 0124047343  |w (OCoLC)879582320 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780124047341  |z Texto completo