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Introductory immunology : basic concepts for interdisciplinary applications /

"Introductory Immunology quickly acquaints readers with natural immune responses manifesting in diseases and disorders. The book presents a complete picture of natural defenses to infectious agents, as well as the mechanisms that lead to autoimmune dysfunction. In addition, it examines immunolo...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Actor, Jeffrey K.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Academic Press, 2014.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; Introductory Immunology; Copyright Page; Contents; Preface; Dedication; Preface; Acknowledgments; 1 A Functional Overview of the Immune System and Immune Components; Immune Homeostasis; Self vs. Non-Self; Innate and Adaptive Immunity; Anatomy of the Immune System; Cells of the Immune System; First Line Defenders: The Myeloid Cells; Adaptive Avengers: The Lymphoid Cells; Lymphocytes; Cluster of Differentiation; Summary; 2 The Inflammatory Response; Inflammation; Initiation of the Inflammatory Response; Role of Antibodies in Inflammation; Biological Functions of Complement.
  • Activation and Directed Migration of LeukocytesPathogen Recognition and Cytokine Signaling; Feedback and Adaptation from a Distance; Summary; 3 The B Lymphocyte and the Humoral Response; B Lymphocytes Produce Antibodies; Structural Characteristics of Immunoglobulins; Immunoglobulin Nomenclature; Biologic Properties of Antibody Isotypes; IgD; IgM; IgG; IgA; IgE; Kinetics of Antibody Response; Membrane-Bound Immunoglobulin; Development of B Cells; Gene Recombination; Development and Selection of Mature B Cells; Activation and Differentiation of B Cells; Summary.
  • Immune Homeostasis and Pathogenic OrganismsMajor Immune Defense Mechanisms Against Pathogens; Physical Barriers to Infection; Anatomic Barrier; Physiologic Barrier; Phagocytic and Endocytic Barriers; Inflammatory Barriers; Bacterial Infections; Microbial Motifs Detected Through Pattern-Recognition Receptors; Mycobacterial Infections; Viral Infections; Human Immunodeficiency Virus; Parasitic Infections (Helminths); Fungal Infections; Evasion of Immune Response; Summary; 6 Basic Disorders of Immune Function; Immunodeficiency Disorders; Genetic Basis for Primary Immunodeficiency.
  • Innate DeficienciesChronic Granulomatous Disease; Leukocyte Adhesion Deficiency; Chediak-Higashi Syndrome; Complement Disorders; Innate Pattern-Recognition Receptor Disorders; Adaptive Immune Disorders; X-Linked (Bruton's) Agammaglobulinemia (X-LA); Selective IgA Deficiency; Common Variable Immunodeficiency; Hyper IgM Disorders; DiGeorge Syndrome; Wiskott-Aldrich Syndrome; Severe Combined Immunodeficiency; Treatment of Immunodeficiency Diseases; Immunodeficiency as a Predisposition to Disease; Human Immunodeficiency Virus and Acquired Immunodeficiency Syndrome; Summary.