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Epigenetics in psychiatry /
Epigenetics in Psychiatry covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cognitive disorders, and the uses of putative epigenetic-based psychotr...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego, CA :
Academic Press,
�2014.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Epigenetics in Psychiatry; Copyright Page; Contents; Preface; About the Editors; List of Contributors; 1 General Aspects of Epigenetics in Psychiatry; 1 Introduction to Epigenetics in Psychiatry; Introduction; Genetics of psychiatric disorders; Schizophrenia; Autism spectrum disorder; Bipolar disorder; Major depressive disorder; Attention deficit hyperactivity disorder; Genotype versus phenotype; Missing heritability; Epigenetics in psychiatric disorders; Nutrition; Prenatal infection; Stress; Epigenetic versus genetic approaches to psychiatric disorders.
- Moving epigenetics forwardConclusion; References; Glossary; 2 Outline of Epigenetics; Introduction; Molecular mechanisms of epigenetics; DNA methylation; DNA methylation, development, and disease; Chromatin remodeling and histone modifications; Histone acetylation; Histone methylation; Other histone modifications; Non-Coding RNA; microRNA; Correlation of epigenetics with genetics, transcriptomics, and proteomics; Clinical and medical implication of epigenetics; Conclusion; Acknowledgments; References; Glossary; 3 A Brief History of Epigenetics in Psychiatry; Introduction.
- Erikson's epigenetic principleSchizophrenia: the epigenetic puzzle; Later theoretical developments; Experimental (laboratory) studies on epigenetics in psychiatry; The social environment and epigenetics in psychiatry; Conclusions; References; Glossary; 4 Roles of Epigenetics in the Neural Stem Cell and Neuron; Outline of neural cell production during cortical development; Epigenetic regulation of exit from cell proliferation cycle toward postmitotic neurons during early cortical development.
- Epigenetic regulation underlying properties of multipotent neural stem cells and their differentiation into upper layer cor ... Epigenetic regulation of postnatal oligodendrocyte differentiation and adult neurogenesis; Combination of trans-acting epigenetic modifiers involved in epigenome formation; Importance of focusing on epigenetics in neuronal functions; Impact of epigenetic regulation on synaptic plasticity, learning, and memory; Plasticity of epigenetic profile in neurons in response to extrinsic stimuli; The robust identity of neurons defined by the epigenetic status.
- Concluding remarksAcknowledgments; References; Glossary; 5 Role of Epigenetics in the Brain; Introduction; Role of epigenetics in evolution; Role of epigenetics in brain development; Brain development; Epigenetics in early brain development; Epigenetics in adult neurogenesis and later brain maturation; Epigenetics and extrinsic factors regulating brain development; Role of epigenetic mechanisms in brain function; Epigenetics and memory; Epigenetics and stress; Epigenetics and cognitive dysfunction; Concluding remarks; Acknowledgments; References; Glossary.