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|a 016831014
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|a 882610681
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|a 9780124171343
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|a 616.8
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|a Epigenetics in psychiatry /
|c edited by Jacob Peedicayil, Dennis R. Grayson, Dimitrios Avramopoulos.
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|a San Diego, CA :
|b Academic Press,
|c �2014.
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|a 1 online resource (664 pages)
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|a text
|b txt
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|a computer
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|2 rdamedia
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|a online resource
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|a Includes index.
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|a Epigenetics in Psychiatry covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cognitive disorders, and the uses of putative epigenetic-based psychotropic drugs. Uniquely, each chapter correlates epigenetics with relevant advances across genomics, transcriptomics, and proteomics. The book acts as a catalyst for further research in this potentially very important and useful area of psychiatry. The elucidation of basic principles o.
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|a Print version record.
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|a Front Cover; Epigenetics in Psychiatry; Copyright Page; Contents; Preface; About the Editors; List of Contributors; 1 General Aspects of Epigenetics in Psychiatry; 1 Introduction to Epigenetics in Psychiatry; Introduction; Genetics of psychiatric disorders; Schizophrenia; Autism spectrum disorder; Bipolar disorder; Major depressive disorder; Attention deficit hyperactivity disorder; Genotype versus phenotype; Missing heritability; Epigenetics in psychiatric disorders; Nutrition; Prenatal infection; Stress; Epigenetic versus genetic approaches to psychiatric disorders.
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|a Moving epigenetics forwardConclusion; References; Glossary; 2 Outline of Epigenetics; Introduction; Molecular mechanisms of epigenetics; DNA methylation; DNA methylation, development, and disease; Chromatin remodeling and histone modifications; Histone acetylation; Histone methylation; Other histone modifications; Non-Coding RNA; microRNA; Correlation of epigenetics with genetics, transcriptomics, and proteomics; Clinical and medical implication of epigenetics; Conclusion; Acknowledgments; References; Glossary; 3 A Brief History of Epigenetics in Psychiatry; Introduction.
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|a Erikson's epigenetic principleSchizophrenia: the epigenetic puzzle; Later theoretical developments; Experimental (laboratory) studies on epigenetics in psychiatry; The social environment and epigenetics in psychiatry; Conclusions; References; Glossary; 4 Roles of Epigenetics in the Neural Stem Cell and Neuron; Outline of neural cell production during cortical development; Epigenetic regulation of exit from cell proliferation cycle toward postmitotic neurons during early cortical development.
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|a Epigenetic regulation underlying properties of multipotent neural stem cells and their differentiation into upper layer cor ... Epigenetic regulation of postnatal oligodendrocyte differentiation and adult neurogenesis; Combination of trans-acting epigenetic modifiers involved in epigenome formation; Importance of focusing on epigenetics in neuronal functions; Impact of epigenetic regulation on synaptic plasticity, learning, and memory; Plasticity of epigenetic profile in neurons in response to extrinsic stimuli; The robust identity of neurons defined by the epigenetic status.
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|a Concluding remarksAcknowledgments; References; Glossary; 5 Role of Epigenetics in the Brain; Introduction; Role of epigenetics in evolution; Role of epigenetics in brain development; Brain development; Epigenetics in early brain development; Epigenetics in adult neurogenesis and later brain maturation; Epigenetics and extrinsic factors regulating brain development; Role of epigenetic mechanisms in brain function; Epigenetics and memory; Epigenetics and stress; Epigenetics and cognitive dysfunction; Concluding remarks; Acknowledgments; References; Glossary.
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|a Mental illness
|x Etiology.
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|a Mental illness
|x Pathophysiology.
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|a Neuropsychiatry.
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|a Mental Disorders
|x etiology
|0 (DNLM)D001523Q000209
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|a Neuropsychiatry
|0 (DNLM)D058027
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|a Maladies mentales
|0 (CaQQLa)201-0001274
|x Physiopathologie.
|0 (CaQQLa)201-0379296
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650 |
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|a Neuropsychiatrie.
|0 (CaQQLa)201-0010249
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|a HEALTH & FITNESS
|x Diseases
|x General.
|2 bisacsh
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|a MEDICAL
|x Clinical Medicine.
|2 bisacsh
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|a MEDICAL
|x Diseases.
|2 bisacsh
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|a MEDICAL
|x Evidence-Based Medicine.
|2 bisacsh
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|a MEDICAL
|x Internal Medicine.
|2 bisacsh
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|a Mental illness
|x Etiology
|2 fast
|0 (OCoLC)fst01016573
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650 |
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7 |
|a Mental illness
|x Pathophysiology
|2 fast
|0 (OCoLC)fst01016584
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|a Neuropsychiatry
|2 fast
|0 (OCoLC)fst01036481
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700 |
1 |
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|a Peedicayil, Jacob.
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700 |
1 |
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|a Grayson, Dennis R.
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700 |
1 |
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|a Avramopoulos, Dimitri.
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776 |
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8 |
|i Print version:
|a Peedicayil, Jacob.
|t Epigenetics in Psychiatry.
|d Burlington : Elsevier Science, 2014
|z 9780124171145
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856 |
4 |
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|u https://sciencedirect.uam.elogim.com/science/book/9780124171145
|z Texto completo
|