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Biochemical and molecular aspects of selected cancers /

This two-volume work not only includes much of the newer molecular biology research but also important earlier research in this area essential for the comprehensive understanding of the biochemistry of neoplastic diseases. As such it will provide an invaluable source of information for the young inv...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Pretlow, Thomas G., Pretlow, Theresa P.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego ; London : Academic Press.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Biochemical and molecular aspects of selected cancers /  |c edited by Thomas G. Pretlow II and Theresa P. Pretlow. 
264 1 |a San Diego ;  |a London :  |b Academic Press. 
300 |a 1 online resource (xii, 542 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
520 |a This two-volume work not only includes much of the newer molecular biology research but also important earlier research in this area essential for the comprehensive understanding of the biochemistry of neoplastic diseases. As such it will provide an invaluable source of information for the young investigator. Human cancers, not experimental models of cancer, are emphasized. 
588 0 |a Print version record. 
505 0 |a Front Cover; Biochemical and Molecular Aspects of Selected Cancers; Copyright Page; Table of Contents; PREFACE; Chapter 1. Chronic Myelogenous Leukemia: A Model for the Genetic and Biochemical Basis of Neoplasia; I. Introduction; II. Clinical Features of Chronic Myelogenous Leukemia; III. The Philadelphia Chromosome; IV. Chronic Myelogenous Leukemia Model Systems; V. Chronic Myelogenous Leukemia Blast Phase: A Model of Tumor Progression ; References; Chapter 2. Structural Basis of Oncogenic Activation of Epidermal Growth Factor Receptor; I. Introduction; II. Domain Structure of ErbB/EGFR 
505 8 |a III. EGFR Signal TransductionIV. Oncogenic Activation of Chicken EGFR and Tissue-Specific Transformation; V. Role of EGFR in Human Oncogenesis; VI. Summary; References; Chapter 3. Colonie Carcinoma: A Common Tumor with Multiple Genomic Abnormalities; I. Introduction; II. Background; III. Molecular Events in Tumor Etiology and Progression; IV. Molecular Alterations in Colorectal Cancer; V. Alterations in Gene Expression; VI. Summary and Speculations; References; Chapter 4. Alterations Associated with Early Neoplasia in the Colon; I. Introduction; II. Biochemical Alterations 
505 8 |a III. Morphological AlterationsIV. Concluding Remarks; References; Chapter 5. Genetic Alterations and Gene Expression in Human Malignant Glioma; I. Introduction; II. Genetic Changes in Glioblastoma Multiforme; III. Expression of Unaltered Genes; IV. Conclusions; References; Chapter 6. Biochemistry of Prostatic Carcinoma; I. Introduction; II. Anatomical and Pathological Context; III. Proliferate Fraction; IV. Whole Nuclear DNA and Cytogenetics; V. Altered Genes and Gene Products; VI. Antigens; VII. Hormones, Enzymes, and Miscellaneous; VIII. Interactions between Epithelium and Mesenchyme 
505 8 |a IX. Models of Prostatic CarcinomaX. Conclusions; References; Chapter 7. Androgen Receptors in Human Prostate Cancer; I. Rationale for Androgen Receptor Studies; II. Ligand-Binding Androgen Receptor Assays in Prostate Cancer; III. Quantitative Androgen Receptor Immunohistochemistry; IV. Image Analysis of Androgen Receptor Immunostaining: Heterogeneity as a Predictor of Response; V. Molecular Analysis of Androgen Receptor Gene Structure and Function in Prostate Cancer; VI. Summary; References; Chapter 8. Biochemistry and Molecular Biology of Skin Tumors; I. Introduction 
505 8 |a II. Mouse Skin Carcinogenesis ModelIII. Human Skin Neoplasia; References; Chapter 9. Alterations in Polyamine Metabolism in Epithelial Tumors of the Skin; I. Introduction; II. Polyamine Metabolism in Mouse Epidermis and Epidermal Tumors; III. Heterogeneity of Ornithine Decarboxylase Expression; IV. Hypotheses and Relevance to Other Systems; References; Chapter 10. Carbohydrate Metabolism and Neoplasia: New Perspectives for Diagnosis and Therapy; I. Significance of Aerobic Glycolysis; II. Role of Phosphometabolite Pools in Cell Proliferation and Tumor Formation 
650 0 |a Cancer  |x Molecular aspects. 
650 0 |a Cancer  |x Genetic aspects. 
650 0 |a Cancer  |x Pathophysiology. 
650 6 |a Cancer  |x Aspect mol�eculaire.  |0 (CaQQLa)201-0212614 
650 6 |a Cancer  |x Aspect g�en�etique.  |0 (CaQQLa)201-0004687 
650 7 |a HEALTH & FITNESS  |x Diseases  |x General.  |2 bisacsh 
650 7 |a MEDICAL  |x Clinical Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Diseases.  |2 bisacsh 
650 7 |a MEDICAL  |x Evidence-Based Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Internal Medicine.  |2 bisacsh 
650 7 |a Cancer  |x Genetic aspects  |2 fast  |0 (OCoLC)fst00845368 
650 7 |a Cancer  |x Molecular aspects  |2 fast  |0 (OCoLC)fst00845397 
650 7 |a Cancer  |x Pathophysiology  |2 fast  |0 (OCoLC)fst00845410 
650 7 |a Tumeurs.  |2 fmesh 
650 7 |a Biochimie.  |2 fmesh 
650 7 |a Biologie mol�eculaire.  |2 fmesh 
650 7 |a Cancer  |x Aspect g�en�etique.  |2 ram 
650 7 |a Cancer  |x Aspect mol�eculaire.  |2 ram 
700 1 |a Pretlow, Thomas G. 
700 1 |a Pretlow, Theresa P. 
776 0 8 |i Print version:  |t Biochemical and molecular aspects of selected cancers  |z 012564499X  |w (DLC) 91017195  |w (OCoLC)31667430 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780125644990  |z Texto completo