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Cell-wide metabolic alterations associated with malignancy /
This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods providing a theoretical overview on metabolic alterations of cancer cells and a series of protocols that can be employed to...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam ; Boston :
Academic Press,
2014.
|
| Edición: | First edition. |
| Colección: | Methods in enzymology ;
v. 543. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
MARC
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| 245 | 0 | 0 | |a Cell-wide metabolic alterations associated with malignancy / |c edited by Lorenzo Galluzzi and Guido Kroemer. |
| 250 | |a First edition. | ||
| 264 | 1 | |a Amsterdam ; |a Boston : |b Academic Press, |c 2014. | |
| 264 | 4 | |c �2014 | |
| 300 | |a 1 online resource (xix, 358 pages, 24 unnumbered pages of plates) : |b illustrations (some color) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
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| 347 | |a data file | ||
| 490 | 1 | |a Methods in enzymology, |x 0076-6879 ; |v v. 543 | |
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a Methods to measure cytoplasmic and mitochondrial Ca2+ concentration using Ca2+ -sensitive dyes -- Methods to measure intracellular Ca2+ fluxes with organelle-targeted aequorin-bsaed probes -- Measuring baseline Ca2+ levels iin subcellular compartments using genetically engineered fluorescent indicators -- Autophagy and autophagic flux in tumor cells -- Methods to assess autophagy in situ-transmisson electron microscopy versus immunohistochemistry -- Methods to measure the enzymatic activity of P13Ks -- Luciferase-based reporter to monitor the transciptional activity of the SIRT3 promoter -- Meabolomic profiling of cultured cancer cells -- Pulsed stable isotope-resolved metaolomic studies -- Single-cell imaging for the study of oncometabolism -- Study of cellular oncometabolism via multidimensional protein identification technology -- In vivo quantitative proteomics for the study of oncometabolism -- Metabolomic profiling of neoplastic lesions in mice -- Metabolomic profiling of tumor-bearing mice -- Metabolomic studies of patient material by high-resolution magic angle spinning nuclear magnetic resonance spectroscopy -- Analysis of metabolomic profiling data acquired on GC-MS. | |
| 520 | |a This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods providing a theoretical overview on metabolic alterations of cancer cells and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo. Malignant cells exhibit metabolic changes when compared to their normal counterparts, owing to both genetic and epigenetic alterations. Although such a metabolic rewiring has recently been indicated as ""yet another"" general hallmark of canc. | ||
| 504 | |a Includes bibliographical references and indexes. | ||
| 650 | 0 | |a Biochemistry. | |
| 650 | 0 | |a Cancer. | |
| 650 | 0 | |a Enzymes. | |
| 650 | 0 | |a Metabolism. | |
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| 650 | 2 | |a Metabolism |0 (DNLM)D008660 | |
| 650 | 2 | |a Biochemistry |0 (DNLM)D001671 | |
| 650 | 2 | |a Enzymes |0 (DNLM)D004798 | |
| 650 | 6 | |a Biochimie. |0 (CaQQLa)201-0001077 | |
| 650 | 6 | |a Cancer. |0 (CaQQLa)201-0004683 | |
| 650 | 6 | |a Enzymes. |0 (CaQQLa)201-0002557 | |
| 650 | 6 | |a M�etabolisme. |0 (CaQQLa)201-0062122 | |
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| 650 | 7 | |a enzyme. |2 aat |0 (CStmoGRI)aat300212647 | |
| 650 | 7 | |a metabolism (biological concept) |2 aat |0 (CStmoGRI)aat300254909 | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Biology. |2 bisacsh | |
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| 650 | 7 | |a Biochemistry |2 fast |0 (OCoLC)fst00831961 | |
| 650 | 7 | |a Cancer |2 fast |0 (OCoLC)fst00845317 | |
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| 700 | 1 | |a Galluzzi, Lorenzo. | |
| 700 | 1 | |a Kroemer, Guido. | |
| 776 | 0 | 8 | |i Print version: |t Cell-wide metabolic alterations associated with malignancy. |b First edition. |d Amsterdam ; Boston : Academic Press, 2014 |z 012801329X |w (OCoLC)879582394 |
| 830 | 0 | |a Methods in enzymology ; |v v. 543. |x 0076-6879 | |
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