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Lesions and transplantation /
Methods in Neurosciences, Volume 7: Lesions and Transplantation describes the chemical and nonchemical production of lesions and preparation and development of transplants, implants, and grafts. This book consists of four sections-chemical and nonchemical lesioning; model systems utilizing lesioning...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego, Calif. :
Academic Press,
[1991]
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| Colección: | Methods in neurosciences ;
v. 7. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Lesions and Transplantation; Copyright Page; Table of Contents; Preface; Methods in Neurosciences; Section I: Chemical and Nonchemical Lesioning; Chapter 1. Lesioning of Rat Nigrostriatal Dopamine Pathway with l-Methyl-4-phenylpyridinium Ion (MPP+); Introduction; Methods; Evaluation of the Lesion; Conclusion; References; Chapter 2. Excitotoxins as Tools for Producing Brain Lesions; Introduction; Excitotoxins: Classification, Comparison, and Mechanisms; Use of Excitotoxins to Make Lesions; Summary; Acknowledgments; References; Chapter 3. Excitotoxin-Lesioned Rat Striatum; Methods
- AcknowledgmentsReferences; Chapter 4. Use of Acromelic Acid for Production of Rat Spinal Lesions ; Acromelic Acid; Injection of Acromelic Acid into Rats and Mice; Kainoid Neurotoxicity; Electrophysiological and Pharmacological Basis; Behavioral Basis; Histological Basis; References; Chapter 5. Use of Ibotenic Acid to Selectively Lesion Brain Structures ; Methods and Procedures; Additional Considerations; Is There Damage to Fibers of Passage following IBO Injections?; Conclusions; Acknowledgments; References; Chapter 6. Monosodium Glutamate (MSG) Lesions; Introduction; Mechanism of Action
- Histology of LesionsProcedures; MSG Syndrome; Histochemical Changes; Summary; References; Chapter 7. Comparison of Electrolytic and Radio-Frequency Lesion Methods; Introduction and Historical Background; Different Effects Observed with Electrolytic and Radio-Frequency Lesions; Production of Electrolytic Lesions; Production of Radio-Frequency Lesions; Production and Verification of Lesions That Leave No Metallic Ion Deposits; Summary and Conclusion; References; Chapter 8. Use of Cold to Reversibly Suppress Local Brain Function in Behaving Animals ; Moveable Cryodes
- Permanently Implanted CryodesAcknowledgment; References; Chapter 9. Chorioretinal Photocoagulation by Different Laser Sources; Introduction; Photocoagulation; Laser Power; Exposure Time; Spot Size; Laser Photocoagulators; Transpupillary Photocoagulation; Transscleral Photocoagulation; Endoocularphotocoagulation; References; Chapter 10. Production of Reversible Local Blockage of Neuronal Function; Introduction; Local Cooling of the CNS; Local Anesthesia; Other Chemicals; Summary; References; Chapter 11. Lesioning the Nucleus Basalis; Introduction; Lesioning Methods; Conclusions; References
- Section II: Model Systems Utilizing LesioningChapter 12. Unilateral MPTP-Lesioned Monkey as an Animal Model for Parkinson's Disease; Parkinson's Disease; 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP); Bilateral versus Unilateral MPTP-Treated Monkeys; MPTP Application; The Unilateral MPTP-Lesioned Monkey; Conclusions; Acknowledgments; References; Chapter 13. MPTP-Induced Parkinsonism in Nonhuman Primates ; Species; MPTP Administration; Clinical Outcome of MPTP Administration; Histological Changes after MPTP Administration; Neurochemical Changes after MPTP Administration