Cargando…
Neurobiology of alcohol dependence /
Recent scientific advances have provided substantial information on the brain circuits and pathways relevant to various aspects of dependence. Neurobiology of Alcohol Dependence highlights the most recent data at the molecular, cellular, neurocircuitry, and behavioral levels, fostering an understand...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London, UK :
Academic Press,
2014.
|
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Half title; Title Page; Copy Right; Contents; Contributors; Preface; Section I: Neurocircuitry of Alcohol Dependence; 1 Frameworks of Alcohol Addiction; Definitions and Conceptual Framework for Negative Reinforcement in Alcoholism; Motivation, Withdrawal, Opponent Process, and Compulsive Use; Animal Models for Compulsive Alcohol Seeking; Neural Substrates of the Negative Emotional State Associated With Alcoholism; Within-System Neuroadaptations that Contribute to the Compulsivity Associated with the Dark Side of Alcoholism.
- Between-System Neuroadaptations that Contribute to Compulsivity Associated with the Dark Side of AlcoholismProtracted Withdrawal; Stress-Induced Reinstatement; Corticotropin-Releasing Factor, Stress, and the Frontal Cortex; Cellular Mechanisms That Mediate the Neuroplasticity of the Dark Side in the Extended Amygdala; Negative Reinforcement in Alcoholism: An Allostatic View; Acknowledgments; References; 2 Cortico-Basal Ganglia Networks and the Neural Substrates of Actions; The Problem of Motivated Behavior; Negative Feedback; Hierarchical Organization; Anticipation and Feedback.
- Pavlovian Conditioning and Anticipatory ControlOperant Behavior and Reinforcement; Control versus Reinforcement; Motivational Hierarchy and Motor Hierarchy; Motivational Hierarchy and Instrumental Learning; Behavioral Analysis of Motivated Behavior; Incentive Value and Outcome Valuation; Manipulations of Instrumental Contingency; Dissociations in Behavioral Control; Distal Feedback and Proximal Feedback; Neural Basis of Motivated Behavior; Localization of Function; Cortico-Basal Ganglia Networks and Motivational Hierarchy; Sensorimotor Network and the Motor Hierarchy.
- Motivational Hierarchy and Distinct Cortico-Basal Ganglia NetworksLimbic Network; Associative Network; Sensorimotor Network; Coordination of Action; Implications for Alcohol Addiction; Habitual Use; Physiological Adaptation and Withdrawal; Conclusions; References; 3 Prefrontal Limbic-Striatal Circuits and Alcohol Addiction in Humans; Introduction; The Prefrontal-Limbic-Striatal Circuit; The Prefrontal Cortex (Lateral PFC, Ventromedial PFC, Orbitofrontal Cortex); Anterior Cingulate Cortex (ACC); Amygdala and Ventral Striatum; Functional Interactions in the Prefrontal-Limbic-Striatal Circuit.
- Acute Effects of Alcohol on the Prefrontal-Limbic-Striatal CircuitAlcohol Addiction and Effects on the Prefrontal-Limbic-Striatal Circuit Function; Dysfunction in the PLS Circuit and Alcohol-Relapse Risk; Conclusions and Future Directions; References; 4 Molecular Adaptations in Mesolimbic Circuitry and Pathological Ethanol Intake; Introduction; Passive versus Active Exposure Models; Ion Channels in the NAcb; Mechanisms and Implication of Adaptations in Ion Channels and Other Molecules; Ion Channels in the VTA; GABA Receptors; Dopamine Receptors; Dopamine Release; Adaptations in the CRF System.